#180 Beta-Blockers & REDUCE-AMI Trial: Beyond Journal Club Segment with NEJM Group

<p>How much do beta blockers help after a heart attack, even when the heart’s pumping well? In this episode, we revisit the origins of <strong>beta blockers in post-MI care</strong>, examine how evidence evolved, and explore the <strong>REDUCE-AMI trial</strong>, which questions whether beta blockers are still needed for all.</p><p>Listen to this latest episode of <strong>Beyond Journal Club</strong>, a collaboration between <strong>Core IM and NEJM</strong> Group, where we put research into context tracing the arc of evidence, dissecting the clinical question, and exploring what the findings could mean for real-world patient care</p><p><br></p><p>🔹 <strong>Sponsor</strong>: <strong>NEJM Fellowship Program, click </strong><a href="coreimpodcast.com/NEJMFellowship"; rel="nofollow"><strong>here to learn more and/or apply</strong></a><strong>!</strong></p><p>🔹 <a href="coreimpodcast.com/2025/06/25/beta-blockers-red…; rel="nofollow"><strong>Transcript and Show Notes</strong></a></p><p><br></p><p><strong>Timestamps:</strong></p><p>(00:48) | Background on Beta Blockers and Their Mechanism</p><p>(02:41) | Historical Context of Beta Blockers in Heart Disease</p><p>(04:56) | Capricorn Trial and Its Impact</p><p>(07:17) | Emergence of Doubts About Beta Blockers</p><p>(10:09) | Introduction to the REDUCED-AMI Trial</p><p>(15:52) | Discussion on Trial Interpretation and Clinical Implications</p><p>(16:18) | Comparison with Other Trials and Future Directions</p><p><br></p><p><strong>Tags:</strong> CoreIM, Internal Medicine, Primary Care, Medical Education, IMCore, Physician Assistant, Nurse Practitioner, Medical Student, Cardiology </p><br /><br />Find the best disability insurance for you: patternlife.com/disability-insurance?campid=49… Sponsors:<br/>* Check out Eko: ekohealth.com<br/>* Check out FIGS and use my code FIGSRX for a great deal: wearfigs.com<br/><br/><br/>A… Inquiries: <a href='redcircle.com/brands'>https://redcircle… & Opt-Out: <a href='redcircle.com/privacy'>https://redcircl…;