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We Shall Finally Map The Brain - EP 36 Andrew Payne
In the 1970s, scientists created the first wiring diagram of a worm brain. To do this, they sliced up a worm, imaged the slices under microscopes and then reconstructed a map of the worm’s neurons and their synaptic connections. Wonderful.
China Builds, The US Regulates - EP 35 Dan Wang
In this episode, Dan Wang comes on the show to discuss his new book Breakneck: China’s Quest to Engineer the Future. I’ll start by noting that the book is fantastic, and you should read it (https://www.amazon.com/Breakneck-Chinas-Quest-Engi
Can California Ever Build Again? - EP 34 Jan Sramek
This week, we bring you the story of California Forever in all its “never told before” glory. For the past eight years, Jan Sramek and a group of wealthy investors have been buying up land in Solano County with the hopes of creating a great
The Man Who Changed Policing In America - EP 33 Rick Smith
Most of you have not heard of Axon Enterprise. But there it is (https://www.axon.com/) – a $57 billion company that has reshaped pretty much every police department in the United States. (San Francisco being the major exception.) Rick Smith
She's Ready To Gene Edit Babies - EP 32 Cathy Tie
Cathy Tie has been having an eventful year. First she co-founded a company determined to gene edit animals and build literal unicorns (https://www.corememory.com/p/the-start-up-bringing-glow-in-the). Then she held a wedding ceremony in Chin
The History And Future Of Brain Implants - EP 31 Sumner Norman
Into the brain we go. Sumner Norman, the co-founder and CEO of Forest Neurotech (https://forestneurotech.org/), comes on the show to take us on a journey across the history and future of brain implants. We start with the first experiments p
Life Beyond Blueprint - EP 30 Bryan Johnson
Well, here we go. Bryan Johnson has come to the pod. You have likely heard an interview with Johnson before, since he’s become such an object of love, hate and fascination among the media over the past couple of years. That said, you will n
How North Korea Infiltrated American Companies With Fake Tech Workers - EP 29 Bob McMillan
For the past few months, The Wall Street Journal’s Bob McMillan (https://www.wsj.com/news/author/robert-mcmillan?gaa_at=eafs&gaa_n=ASWzDAh3UxQ84eFRmSQLO96u7jssP7VZT6nGULGnIHp96mg8b3U5YjPNUeLmwN7Ulfs%3D&gaa_ts=689c8f80&gaa_sig=Q2F6MugS9d2wYw
The Company Putting A Score On Your Life - EP 28 Dugal Bain-Kim
We are awash in longevity tests and services. There are ones that measure your blood, others that measure the quality of your DNA and others that check on your gut and brain. You can Blueprint, Viome, Function Health and on and on. To figur
The Forrest Gump of Silicon Valley - EP 27 Leslie Berlin
This week’s guest is Leslie Berlin, the author, historian and executive director of the Steve Jobs Archive. My first encounter with Berlin’s work happened when I picked up The Man Behind the Microchip: Robert Noyce and the Invention of Sili
The Iranian Scientist Leading America’s Nuclear Rebirth - EP 26 Kurt Terrani
Our guests this week are Kurt Terrani, an Iranian-born nuclear scientist, and Tommy Hendrix, a Green Beret turned venture capitalist, and they arrive with an exceptional story. Terrani is the co-founder and CEO of Standard Nuclear (https://
Her Multi-Billion Dollar Quest to End Disease - EP 25 Priscilla Chan
Ten years ago, Dr. Priscilla Chan and Mark Zuckerberg vowed to aim almost all of their billions at a singular goal: “to cure, prevent and manage all disease by the end of this century.” Dr. Chan recently visited the Core Memory podcast stud
Spaceplanes Are Upon Us - EP 24 Stefan Powell
Last November, Dawn Aerospace broke some aerospace records. Its spaceplane – the Mk-II Aurora – hit Mach 1.1 on its way to climbing to 20km faster than any aircraft that has ever taken off from a runway. (The previous record was set by an F
The Child Prodigy Teaching Other People How To Learn
Andrew Hsu has been something of a legend for most of his life. In 2007, The Seattle Times published a story (https://www.seattletimes.com/seattle-news/3-degrees-arent-enough-for-16-year-old-uw-grad/) documenting Hsu’s graduation from the U
Fixing American Science Funding
This week on the Core Memory podcast – we fix American science and advance civilization. We were joined by Anastasia Gamick and Adam Marbleston from Convergent Research. They’ve spent the last few years pioneering a new model of science fun
The New Era of Consumer DNA Tests
This week’s guest is Kian Sadeghi, the founder and CEO of Nucleus (https://mynucleus.com/). Sadeghi has everything you want in a controversialish bio-tech CEO. He’s a college dropout, a Thiel Fellow and a “wild child,” as one Nucleus invest
An AI Engineer Is Here, and It Might Redesign the Physical World - EP 20 Paul Eremenko
The news here is that Paul Eremenko has a new start-up called P-1 AI (https://p-1.ai/). Eremenko is billing P-1 as one of the first stabs at building an AI engineer. The company’s “Archie” AI can help with day-to-day engineering tasks today
The Future of Money - EP 19 Zach Abrams
More than a decade ago, someone I respect told me to go meet these young, Irish brothers - Patrick and John Collison. The brothers had started a small company called Stripe, and my friend assured me they were primed to accomplish big things
Anduril and Meta Make Peace to Make War Together - EP 18 Palmer Luckey
Palmer Luckey has come on the Core Memory podcast today to deliver some full-on shocking news. (And top tips on raising children as well.) As you’ll hear on the show, Luckey’s company Anduril has partnered with Meta to create a product for
Peter Beck on Rockets, Dinner with Elon and the Future of Space
The facts are these: Peter Beck is the founder and CEO of Rocket Lab, and Rocket Lab is an absolute beast in the aerospace world. It has launched more than 60 times from spaceports in New Zealand and the US and is in the midst of creating a
He Comes Promising AI Freedom For All
Back when I first began covering technology in the early 2000s, my favorite thing to write about was open source software. I was young and idealistic, and the hardcore free software and open source zealots spoke to me. Code was meant to be
The Company Trying to Reprogram Aging
First. The news. The bio-tech player New Limit (https://www.newlimit.com/) has raised $130 million from just about the fanciest assembly of smart, rich people imaginable. Nat Friedman and Daniel Gross – via NFDG - Kleiner Perkins, Khosla Ve
A Brain Researcher's Bid to Make Digital Twins of Humans
Earlier this month, Nature published (https://www.nature.com/immersive/d42859-025-00001-w/index.html) some of the results from a multi-year effort to better understand the visual cortex of mice. The work took place under the MICrONS (https:
Coinbase CEO Brian Armstrong on the Evolving Future of Humans
Coinbase CEO and co-founder Brian Armstrong joins the pod to discuss crypto, crypto, crypto. Well, not really. Everyone asks Armstrong about crypto all the time, so we decided to head in a different direction and focus on his life and his i
Chris Kemp on Astra's Comeback, Rockets and Drones from Space
If you’ve seen HBO’s Wild, Wild Space (https://play.max.com/movie/55ee21e5-4295-4107-859a-a97decf2eebf) or read When the Heavens Went on Sale (https://www.amazon.com/gp/aw/d/0062998870/ref=tmm_hrd_swatch_0?ie=UTF8&qid=&sr=), then Chris Kemp
Dwarkesh Patel Wants People to Learn Things
We flipped the tables on Dwarkesh Patel this week and turned the podcaster into the podcastee. Over the past few years, Patel has made a name for himself as a stellar interviewer of interesting people. Whether questioning a scientist, histo
The First Bungee Jump, Space Weapons, Lunar Landers and Airships: Al Weston Has Done It All
A few years ago, I caught wind that Sergey Brin had started funding an airship start-up called LTA (Lighter Than Air) Research. After hitting up some sources, I came to learn that the man heading up the airship venture was Dr. Alan Weston.
Engineering Brains - EP 09 Max Hodak
Few figures in Brain Computer Interface Land can match Max Hodak’s output over the past decade. He helped start Neuralink in 2016 and then went on to start Science Corp. in 2021. Science has been working on implants to help restore vision (
Consciousness in the Quantum Realm
For the past decade, the scientist Suzanne Gildert has been working to imbue robots and AIs with new skills. She co-founded a pair of start-ups - Kindred and Sanctuary AI - that strove to add intelligence to robotic arms and bodies. The res
On Steve Jobs, Drugs, AI, Risk and the Enduring Magic of Silicon Valley
Don’t meet your heroes unless your hero is John Markoff. For he is as good as billed. No one has broken more stories about the technology industry or documented more of Silicon Valley’s most crucial moments than Markoff, the longtime scribe
