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Endocrine Deep Dives

von Gurbir Gill, MD

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  1. Ovarian steroidogenesis

    In this episode we unpack the intricate biochemistry of ovarian steroidogenesis, focusing on the cooperative two-cell two-gonadotropin architecture between theca and granulosa cells. We trace cellular pathways from cholesterol transport via

  2. Ovarian folliculogenesis

    This episode provides a deep clinical breakdown of human folliculogenesis, tracing the 375-day trajectory from primordial activation to dominant follicle selection. We explore the transition from gonadotropin-independent paracrine pathways

  3. Hyperprolactinemia

    This episode breaks down the complex etiology and diagnostic pitfalls of hyperprolactinemia, shifting from normal physiologic responses like pregnancy to drug-induced elevations from antipsychotics and prokinetics. We analyze critical labor

  4. Joy of osteoporosis coding (guide in description)

    This episode goes into the intricacies of osteoporosis coding. https://share.jotbird.com/soft-steady-mesa-willow

  5. Trabecular bone score

    In this episode, we dive into the Trabecular Bone Score, a groundbreaking imaging tool redefining how we assess skeletal health. While traditional bone density scans only measure mineral quantity, this technology evaluates the internal micr

  6. Basics of Medicare parts A-D

    This episode is my take on understanding the basics or Medicare insurance. More episodes to come.

  7. Acromegaly Management

    This episode breaks down the clinical management matrix for acromegaly, providing an advanced roadmap for endocrinologists managing growth hormone hypersecretion. We review transsphenoidal surgery guidelines, post-operative remission metric

  8. Acromegaly Diagnosis

    This episode explores the clinical progression, diagnosis, and long term management of acromegaly, a rare condition driven by chronic growth hormone excess. We trace the patient journey from early subtle metabolic shifts to irreversible ske

  9. Acromegaly pathophysiology

    In this episode, we break down the complex pathophysiological and genetic landscape of acromegaly, looking beyond the simple diagnosis of growth hormone hypersecretion. We explore the critical cellular differences between densely and sparse

  10. MASLD and MASH

    This episode delivers a comprehensive clinical review of metabolic dysfunction associated steatotic liver disease (MASLD) and its progressive stage, metabolic dysfunction associated steatohepatitis (MASH). We explore the multi organ pathoge

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