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How Existing Disease Surveillance Networks Can Catch New Outbreaks | Before the Outbreak, Episode 2
Many of our best surveillance tools today that were originally built to target specific diseases like polio and malaria have become critical infrastructure for outbreak response and early warning across a wide range of pathogens. This inclu
Introducing: "Before the Outbreak" — A Three-Part Series on Disease Surveillance and Pandemic Preparedness
Robust disease surveillance systems are the foundation of strong public health systems and are essential to preventing, detecting, and responding to health threats before they escalate. Commitments to and investments in quality disease surv
How To Prevent Weapons of Mass Destruction in a Changing Geopolitical and Military Landscape | Global Catastrophic Risks
Today's episode is produced in partnership with the Global Challenges Foundation. The foundation is dedicated to raising awareness of global catastrophic risks and strengthening global governance to address them. The Global Challenges Found
The Case Against Rodrigo Duterte at the International Criminal Court
One year ago, in 2025, former Philippine President Rodrigo Duterte was extradited to The Hague to face charges of crimes against humanity and murder for orchestrating a campaign of extrajudicial killings against people he deemed to be invol
Is Cuba Next?
For the first time in nearly 70 years, it looks like there may be major political changes afoot in Cuba — driven by the United States. The Trump administration has been ratcheting up pressure on the island, including by imposing an oil emba
The Iran War Ignites a Global Humanitarian Emergency
Earlier last last week, he United Nations reported that around 300,000 Lebanese had been displaced since Israel opened a new front in southern Lebanon amid this widening regional conflict. Yesterday, that figure surged to more than 800,000
How to Prevent Catastrophic Climate Change | Global Catastrophic Risks
Today's episode is produced in partnership with the Global Challenges Foundation. The Foundation is dedicated to raising awareness of global catastrophic risks and strengthening global governance to address them. Global Challenges Foundatio
The War in Iran Comes to the UN | To Save Us From Hell
We cover a lot of ground in this week's episode of To Save Us From Hell! There are two new entrants to the race to succeed António Guterres as the next UN Secretary-General; Cindy McCain announced she is stepping down as head of the World F
How Does The Iran War End?
Things are obviously moving very fast in the Middle East. When I caught up with my guest today, Dalia Dassa Kaye, the war was in its second day. Bombings in Iran and throughout the region continued at a rapid clip, and there was little sens
Anthropic vs. the Pentagon: The High-Stakes Fight Over Military AI—and Autonomous Weapons
Earlier this week, Defense Secretary Pete Hegseth held a high-stakes meeting with Anthropic CEO Dario Amodei and, according to several news reports, delivered an ultimatum: either Anthropic drops the safety guardrails built into its AI mode
Ethiopia Is Sliding Fast Toward Major War
Ethiopia is on the brink of a war that could turn into a major regional conflagration. Over the past several weeks, military forces have been moving into position across the region in a conflict that would pit the government of Ethiopia and
Board of Peace v United Nations | US To Attack Iran? - To Save Us From Hell
It was an odd juxtaposition: Trump's inaugural Board of Peace gathered in Washington, D.C. as the U.S. appeared to be readying for war with Iran. In this week's To Save Us From Hell episode, Mark and Anjali discuss why this Board of Peace c
Why Has the United States Deployed Gunboats to Haiti?
On February 3, the United States deployed a warship and Coast Guard vessels off the coast of Haiti, near Port-au-Prince. The move came amid political wrangling within Haiti's Transitional Presidential Council, as some members sought to bloc
The Last Nuclear Arms Control Agreement Between the US and Russia Just Expired. What's Next?
The New START treaty, signed by the United States and Russia in 2010, limited both countries to 1,550 deployed strategic warheads, placed restrictions on how those weapons could be deployed, and included strong verification mechanisms to en
Spain's Prime Minister Pedro Sánchez Is Rewriting the Political Playbook
Donald Trump doesn't much like Pedro Sánchez — and the Spanish prime minister is perfectly fine with that. Unlike other European leaders who reflexively genuflect to the American president, Pedro Sánchez stands apart for his willingness to
The Secretary General Race Heats Up — And the Epstein Files Hit the UN | To Save Us From Hell
For the first time in history, multiple countries have jointly nominated a candidate for UN Secretary General. Earlier this week, Brazil, Chile, and Mexico endorsed Michelle Bachelet—a former president of Chile, former UN High Commissioner
What Americans Really Think About Foreign Policy
The Chicago Council on Global Affairs has been tracking American views on foreign policy since the end of the Vietnam War. Last week, it released its 2025 survey—and the results point to a widening partisan divide on some of the most fundam
Civil War Has Returned to South Sudan
For the past year and a half, South Sudan has been on the brink of a new civil war. A 2018 peace deal that ended the last civil war has been faltering, while the war across the border in Sudan has threatened to spill south. According to my
One Year On: What Have Trump's HIV/AIDS Cuts Cost The World?
One year ago, the United States was winning the global fight against HIV/AIDS. Thanks largely to American leadership, infections and deaths from HIV/AIDS have dropped precipitously over the past 20 years, ever since the U.S. government made
The Stories that Will Drive the UN Agenda in 2026 | To Save Us From Hell
Can Donald Trump's new Board of Peace really compete with the Security Council? Will we even be discussing it a week or two from now, or will Trump and other world leaders simply move on? And what's with the Board's logo, which looks almost
Why a U.S. Strike Against Iran May Backfire
Protests sweeping Iran are unlike anything the regime has faced since coming to power in 1979. What began as demonstrations by shopkeepers in Tehran over the sharply devalued Iranian rial quickly morphed into sustained, nationwide anti-gove
The Curious Case of America's Christmas Day Missile Strikes in Nigeria
On Christmas Day, the United States launched a series of missile strikes in Nigeria, ostensibly against jihadist groups. In the weeks prior, Donald Trump had been claiming that Christians in Nigeria were being subjected to systematic attack
The View from Denmark as Trump Threatens Greenland | Søren Lippert
Danes are reeling from the aggressive nature of Donald Trump's designs on Greenland — but there is little they can do to stop the United States from acquiring the territory, whether by force or coercion. This is an odd position for Denmark,
How China is Responding to the "Donroe Doctrine"
I'm joined by one of my favorite fellow podcasters and Substackers, Kaiser Kuo, host of the long-running Sinica Podcast, for a wide-ranging conversation on China, Venezuela, and America's shifting role in the world. We start by unpacking ho
Is This an Existential Moment for the United Nations? | To Save Us From Hell
The Security Council convened an emergency meeting on Monday in response to American military operations in Venezuela that captured Nicolás Maduro and his wife— forcing dozens of countries to publicly respond to one of the most audacious U.
The U.S. Just Toppled Nicolás Maduro. Here Are the Major Risks
In a stunning U.S. military operation carried out in the early hours of Saturday, January 3rd, American forces captured Venezuelan President Nicolás Maduro and his wife. As of Saturday afternoon Eastern Time, the two were en route to New Yo
How to Revive a Global Plastics Pollution Treaty | When Treaties Work
In 2022, countries agreed to negotiate an international treaty to end plastics pollution. They gave themselves a two-year deadline to finalize the treaty text — and needless to say, that deadline has not been met. The conventional wisdom is
How to Prevent Ecological Collapse | Global Catastrophic Risks
Today's episode is produced in partnership with the Global Challenges Foundation. The Foundation is dedicated to raising awareness of global catastrophic risks and strengthening global governance to address them. Global Challenges Foundatio
To Save Us From Hell | Anjali Addresses the Security Council! Plus: Rafael Grossi Gets "The New Yorker" Profile Treatment
Your very own To Save Us From Hell co-host Anjali Dayal briefed the United Nations Security Council on Monday! She was paired with former UN Secretary-General Ban Ki-moon for a special meeting of the Council dedicated to examining the role
When Treaties Work | The Rome Statute for the International Criminal Court
In 1998, 120 countries came together to adopt the Rome Statute, creating what would become the International Criminal Court. Four years later, that treaty entered into force, and the ICC officially opened its doors as a permanent court task
