Chronic Lymphocytic Leukemia — Microlearning Activity 1

Featuring perspectives from Dr Catherine C Coombs, including the following topics:
• Early versus delayed addition of obinutuzumab to acalabrutinib and venetoclax in treatment-naïve chronic lymphocytic leukemia (CLL) (0:00)
• Feasibility of discontinuation of Bruton tyrosine kinase (BTK) inhibitor therapy in CLL; minimal residual disease and disease monitoring (4:10)
• Ongoing Phase III trials of BTK inhibitor/B-cell lymphoma 2 inhibitor combinations in previously untreated CLL (10:05)
• Pirtobrutinib as first-line therapy for CLL and long-term safety data (15:22)

CME information and select publications (researchtopractice.com/SOHO2026/CLL/Micro1/Video)