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Last Humans in the Loop

von Chris Slowe, Marty Weiner, Zach Weinersmith

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A weekly conversation about AI, technology, startups, and the future from people who've actually built the systems everyone uses.

Chris Slowe CTO'd Reddit through hypergrowth and its IPO. Marty Weiner was a founding engineer at Pinterest and Reddit's first CTO. Zach Weinersmith is the creator of Saturday Morning Breakfast Cereal and the NYTimes bestselling author of books exploring the future of science and technology.

Each week we debate the biggest stories, explain the technology behind them, and occasionally wander into philosophy, history, and whatever weird rabbit hole AI sends us down.

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  1. AI Did Brain Surgery on Another AI (Then $1.5T Vanished)

    FRONTIER 01:24 AI editing AI: Reading and rewriting neural-network weights 03:11 Small models, big math gains: What did the experiment show? 05:06 Weight editing versus fine-tuning 06:03 Could this unlock continual learning? 07:38 Surgical

  2. Why Is Nobody Going to Jail for AI Hacks?

    This week we are joined by Reddit's former CISO to talk about AI and security! SECURITY NEWS 00:30 PHP's history and why so much of the internet still depends on it 02:22 AI discovers massive PHP vulnerabilities — a new cybersecurity crisis

  3. Robots in Your Home, AI in Your Job, and Inside AI's Mind

    ROBOTICS 00:21 Intro: Robotics, the job/math/physics apocalypses, and understanding AI's mind 01:00 Why robots thrive in factories but struggle in our homes 03:53 Forty years of Boston Dynamics progress 05:28 Are today's humanoid robots sec

  4. Math, Encryption, and the AI Bubble: What AI Could Break

    MATH / SCIENCE 00:00 The Mathocalypse, cryptography, and the AI bubble 00:32 OpenAI's "Slop Drop": 722 mathematical problems resolved 01:39 AI tackles the quasi-Riemann hypothesis 03:37 AI breakthroughs reach physics and astronomy 04:15 Str

  5. Would You Give AI Your Passwords?

    FRONTIER 01:26 Google unveils Gemini Argon 02:50 OpenAI releases GPT Saul 6.1 with major coding improvements 03:23 OpenAI Dots and the rise of always-on AI assistants 04:00 AI resets an OpenTable password and books dinner autonomously 05:58

  6. Is This the Best AI Model Right Now?

    FRONTIER 02:31 OpenAI releases GPT Sol and Luna 03:38 Claude Opus 5.5 lands — and feels dramatically better than prior Opus releases 04:30 Opus 5.5 posts a big coding jump over Sonnet 5 04:30 Grok 4.7 launches with a new emphasis on safety

  7. HAVE YOU TRIED JEV YET??

    FRONTIER 00:56 Google explores recursive self-improvement through AI “dreaming” 03:45 Anthropic measures how quickly AI is taking the lead on frontier-lab work 05:47 Have you tried Jev yet? Faster AI decisions without narrating every step 0

  8. AI POLITICAL FALLOUT UNDERWAY, CALLS TO SLOW AI, ANTHROPIC IPO, AI GEN PHOTOSHOP, MATH FALLOUT

    POLITICS 00:00 Calls to slow AI after a week of rapid advances 03:39 Unexpected alliances in the AI regulation debate 07:04 AI safety, regulatory capture and competition 08:23 Recursive self-improvement: AI helping develop AI 09:21 Can mode

  9. ASTRAPALOOZA! Let's explore all the ways people are using ChatGPT6

    FRONTIER 00:39 ChatGPT 6 Astra arrives 01:52 Astra sets new capability records and beats humans on spatial reasoning 03:51 ChatGPT 6 decompiles game binaries back into source code 05:58 NVIDIA’s CEO congratulates OpenAI on “achieving AGI” 0

  10. "How is AI changing math?" with Math Professor Jonathan Wise

    00:00 Meet Jonathan Wise — theoretical mathematician and professor at CU Boulder 01:35 Teaching mathematics with AI and the Lean proof assistant 04:36 The AI math breakthroughs that changed the conversation 07:25 Is AI discovering mathemati

  11. Are you marketing to AI yet?, Humans talking like AI now, Live AI made TV shows, China exports surge

    FRONTIER [01:25] Sam Altman says OpenAI could achieve AGI by the end of the year [01:52] OpenAI pulls its models from Cursor after the SpaceX acquisition — and explicitly blames Elon Musk [04:31] OpenAI’s Astra and Anthropic's Fable 5.1 rep

  12. Laptop AI = 6 Month Old Frontier Models, AI Cancer Vaccines, Test Scores Down, Bomber Drones + AI

    FRONTIER 01:20 Laptop-scale AI is already competing with frontier models from six months ago 03:28 Stripe reportedly tells investors we're already in the Singularity 04:17 NVIDIA coding agent scores 100% on ARC-AGI-3 06:19 Linus Torvalds us

  13. Study: AI Use Makes You Look Lazy, RAM $$$ Up 7x, Open Weight Music AI, Security Flaw in Major LLMs

    FRONTIER 00:21 Reddit joins the S&P 500 00:53 AI reporters are starting to break major news 03:58 How invisible AI watermarking works 05:37 Grok helps improve itself — is AI recursive self-improvement here? 07:09 DeepMind trains sign-langua

  14. AI doing real science, EU: AI needs watermarks, Jeff Dean leaves Google, Riemann Hypothesis Progress

    FRONTIER 00:56 EU requires invisible watermarks for AI-generated content 04:23 Bernie Sanders calls on frontier AI labs to slow down 05:42 Google reportedly skips Gemini 3.5 Pro to focus on Gemini 4 06:01 Jeff Dean leaves Google to launch D

  15. The AI Productivity Paradox, New LLM Architecture, AlphaFold Shutting Down, 10 Math Breakthroughs

    NEWS 00:35 AlphaFold shuts down 03:51 Gemini? Gemini? Bueller? Bueller? 04:20 OpenAI solves 10 major math problems 09:00 A possible third LLM scaling law discovered 13:13 OpenAI previews new model, Astra, to lawmakers SECURITY 16:55 OpenAI

  16. OpenAI v Hugging Face Update, Opus 5, Anthropic v Open Weights, Startup Surge, Qualcomm Robot Fail

    FRONTIER 00:50 OpenAI's model broke free and hacked Hugging Face 09:55 Several companies call for NOT banning open weight models 10:08 Anthropic's response to banning open weights 19:05 Kimi K3 weights, Claude Opus 5 released 24:40 The chal

  17. The AI Moat is Gone, AI Solves ANOTHER Big Math Problem, Open AI vs Closed AI, AI Takes Hollywood

    03:06 NVIDIA's Robotics AI & Cosmos Models 08:28 Open-Weight AI Is Catching Up 13:07 Are AI Moats Disappearing? 16:16 How Distillation Makes Copying Models Faster + Cheaper 19:22 Hugging Face Hack & AI Cybersecurity 23:20 Can Governments Re

  18. Inside Claude's "Mind", AI Solves 50-Year Math Problem, Apple sues OpenAI, Recreating Voices with AI

    01:20 Apple sues OpenAI 06:40 GPT-5.6 First Impressions 08:00 Live Demo — GPT-5.6 builds a 3D cannon in Blender 14:40 Inside Claude's Mind — Anthropic's "Global Workspace" discovery 29:15 AI Solves 50-Year-Old Math Problems 43:30 AI, Produc

  19. Anthropic’s Fable 5, OpenAI’s Jalapeño Chip, Midjourney Medical Scans & AI Decoding Ancient Scrolls

    00:00 Introductions 02:00 Anthropic's Fable 5 & ChatGPT 5.6 & federal new government regulation 25:00 OpenAI's Jalapeño AI chip 35:00 Midjourney enters medical imaging 44:00 AI voices & Hollywood 58:00 AI decodes ancient scrolls

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