Prevent Alzheimer's with Peptides? | Lifespan with Dr. David Sinclair - S2, Ep. 12

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Could peptides help us heal faster, protect our brains, and even live longer?
In this episode, David and Matt ask the questions we all want to ask. Could peptides such as humanin help protect the brain against Alzheimer’s disease? Can they accelerate healing, repair damaged tissues, ease arthritis, or improve muscle and gut health? Might they eventually offer new ways to treat age-related diseases? They also separate promising science from hype, examining which peptides have credible evidence from human studies, which remain experimental, and what we know about their safety. The conversation also looks at the first FDA-approved medicine designed to target mitochondria.

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Our selected partners make it easy for the Lifespan audience to access tools and technologies featured in this episode – from Ketone-IQ’s exogenous ketones as an alternative brain fuel, to WHOOP’s wearable tracking of recovery, strain, and sleep, to Sunlighten’s patented, high-heat infrared saunas designed to support mitochondrial function, heart health, and energy.

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○ WHOOP: Get a free WHOOP band and one month of membership at join.whoop.com/LIFESPAN or with code LIFESPAN

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Legal & Medical Disclaimers

The Lifespan show and all related content are provided for informational and educational purposes only and are not intended as medical advice, diagnosis, or treatment. Nothing presented should be interpreted as a recommendation to diagnose, treat, cure, or prevent any disease or medical condition. This content is not a substitute for professional medical advice, diagnosis, or treatment from a qualified healthcare provider.

You should always consult with a licensed physician or other qualified healthcare professional before making decisions about your health, including starting, stopping, or modifying any treatment, supplement, diet, or exercise program.

The information shared reflects the views and opinions of the host and guests and is based on the scientific literature, their experience and expertise, and general wellness principles. Listening to or engaging with Lifespan content does not establish a doctor–patient or clinical relationship.

Health and longevity outcomes can vary significantly between individuals. Any references to studies, interventions, products, or protocols are not guarantees of specific results, and individual responses may differ.

From time to time, Lifespan may discuss or partner with third-party products or services. These references are provided for informational purposes only and should not be considered medical recommendations or endorsements of efficacy for any individual.

Lifespan Foundation is an independent 501(c)(3) non-profit organization whose mission is to support medical research.

The views expressed by Dr. David Sinclair, A.O., Ph.D., are his own and do not represent those of Harvard University, Harvard Medical School, or any affiliated institutions.