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NEJM AI Grand Rounds, hosted by Arjun (Raj) Manrai, Ph.D. and Andrew Beam, Ph.D., features informal conversations with a variety of unique experts exploring the deep issues at the intersection of artificial intelligence, machine learning, and medicine. You’ll learn how AI will change clinical practice and healthcare, how it will impact the patient experience, and about the people who are pushing for innovation. Whether you are an AI researcher or a practicing clinician, these conversations will enlighten and surprise you as we journey through this very exciting field. Produced by NEJM Group.
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Abridge’s Dr. Michal Nedoszytko on Physicians Who Build Software
Dr. Michał Nedoszytko (https://mcdn.podbean.com/mf/web/iwbjnucpwx79gd27/Nedoszytko_bio.pdf), clinician scientist at Abridge and interventional cardiologist, has spent two decades building software alongside clinical practice. He explains ho
Beyond the Hype: Dr. Xiao Liu on Evaluating Medical AI
The promise of medical AI is not simply better performance — it is better care grounded in evidence patients and clinicians can trust. Dr. Xiao Liu (https://mcdn.podbean.com/mf/web/vujqf5ttx5pptkur/Liu_bio.pdf), a clinician and medical AI r
Dr. Suchi Saria on Building AI That Changes Care
A patient can deteriorate while the warning signs remain buried in a noisy electronic record. Dr. Suchi Saria (https://mcdn.podbean.com/mf/web/gh37nxhq9yev8qcv/Suchi_Saria_bio.docx), Founder and CEO of Bayesian Health and a faculty member a
Weave’s Brandon Rice on Rebuilding Drug Regulation with AI
Brandon Rice (https://mcdn.podbean.com/mf/web/pfr292hwmz6i7aug/Brandon_Rice_Bio.pdf) believes that improving health care sometimes means improving the systems behind it. Through his work at Weave, he focuses on modernizing the regulatory in
OpenAI’s Karan Singal on HealthBench and the Future of Medical AI
Medical expertise has always been scarce. Dr. Karan Singal (https://mcdn.podbean.com/mf/web/zgwsjz7jvtane9rp/Karan_Singhal_bio.pdf) believes AI can help change that. Drawing on his work at OpenAI and earlier efforts behind Med‑PaLM, he disc
The OpenEvidence Episode: Dr. Travis Zack on the Future of Clinical Evidence
Dr. Travis Zack (https://mcdn.podbean.com/mf/web/cmzqfx7q7wcgm27i/Travis_Zack_short_bio.pdf), Chief Medical Officer of OpenEvidence, takes us behind the scenes of the start and growth of the company, and brings a clinician’s perspective to
Doctronic’s Autonomous AI with Dr. Byron Crowe
Doctronic CMO Dr. Byron Crowe (https://mcdn.podbean.com/mf/web/xsz4vhedu2s4fpyn/ByronCrowebio.pdf) describes how administrative complexity can interfere with timely, effective treatment, and how AI may help address those challenges. Crowe d
AI’s Next Frontier with Dr. Kyunghyun Cho
Dr. Kyunghyun Cho (https://kyunghyuncho.me/) is a leading AI researcher best known for co-authoring a landmark 2014 paper that introduced neural machine translation. In this episode, he discusses his wide-ranging career spanning fundamental
Epic’s Approach to AI with Seth Hain
Clinical AI only helps patients if clinicians and health systems trust it. Seth Hain (https://www.linkedin.com/in/seth-hain-12760647/) describes how Epic is building foundation models that respect institutional autonomy, minimize burden, an
Bridging AI and Biology to Tackle Medicine’s Hardest Problems with Dr. Marinka Zitnik
For Dr. Marinka Zitnik (https://dbmi.hms.harvard.edu/people/marinka-zitnik), the promise of AI in medicine begins with acknowledging the scale of the problem. Most patients with rare diseases have no approved treatments, and traditional dru
What Values are in AI? A Conversation with Dr. Zak Kohane
For Dr. Zak Kohane (https://dbmi.hms.harvard.edu/people/isaac-kohane), this year’s advances in AI weren’t abstract. They were personal, practical, and deeply tied to care. After decades studying clinical data and diagnostic uncertainty, he
From Hindsight Bias to Machine Bias: Dr. Laura Zwaan on Learning from Mistakes
As a cognitive psychologist, Dr. Laura Zwaan (https://mcdn.podbean.com/mf/web/bisywfhwes5yiv7i/Biography_Laura_Zwaan.pdf) studies how humans make—and learn from—mistakes. In this episode of NEJM AI Grand Rounds, she brings that lens to AI,
Medicine, Machines, and Magic: Dr. Jonathan Chen on Medical AI
In this episode, Dr. Jonathan Chen (https://mcdn.podbean.com/mf/web/rdb6wgcbxg3je2ed/Jonathan_Chen_Bio.docx) joins the hosts to discuss his path from teenage programmer to Stanford physician-informatician and why machine learning has both t
From Clinician to Chief Health AI Officer: A Conversation with Dr. Karandeep Singh
Dr. Karandeep Singh (https://mcdn.podbean.com/mf/web/sgsah5beyn8n36mi/Karandeep_Singh_Bio.pdf) brings two worlds together: programming and medicine. In this conversation, he explains how early experiments with code led him to biomedical inf
Radiologist Turned CEO: Dr. Jeremy Friese on AI for Prior Authorization
Dr. Jeremy Friese (https://mcdn.podbean.com/mf/web/b764hia3speigd3g/Jeremy_Friese_MD_MBA_Humata_Biosketch_2025aihzm.pdf) knows medicine from both sides. A practicing radiologist and technology executive, he’s seen firsthand how administrati
Can AI Accelerate Science? Dr. Andy Beam on AI’s Next Frontier
Dr. Andy Beam (https://mcdn.podbean.com/mf/web/w5aftmmy3fux99mq/Episode_32_Beam_bio.pdf) has trained models, mentored scientists, and used data to quantify the value of treatments. In this episode of NEJM AI Grand Rounds, Raj Manrai turns t
Google’s Efforts to Build Patient-Facing AI: A Conversation with Drs. Alan Karthikesalingam and Anil Palepu
In this episode of NEJM AI Grand Rounds, guests Drs. Alan Karthikesalingam (https://research.google/people/107444/?&type=google) and Anil Palepu (https://research.google/people/anilpalepu/?&type=google) of Google walk co-hosts Raj Manrai an
Rewriting the Clinical Playbook: Dr. Shiv Rao on Scaling Empathy with AI
Dr. Shiv Rao (https://www.abridge.com/bio/shiv-rao), cardiologist and CEO of Abridge, joins hosts Raj Manrai and Andy Beam on NEJM AI Grand Rounds for an inspiring conversation at the intersection of medicine, technology, and meaning. Shiv
Pixels to Protocols: Building the AI Future of Pathology with Dr. Faisal Mahmood
Dr. Faisal Mahmood (https://dms.hms.harvard.edu/people/faisal-mahmood), Associate Professor of Pathology at Brigham and Women’s Hospital and Harvard Medical School, joins hosts Raj Manrai and Andy Beam on NEJM AI Grand Rounds to explore the
From Bedside to Boardroom: How AI, Multi-Omics, and New Business Models Are Shaping the Biomedical Frontier with Morgan Cheatham
Morgan Cheatham (https://www.bvp.com/team/morgan-cheatham) joins hosts Raj Manrai and Andy Beam on NEJM AI Grand Rounds to discuss the evolving landscape of artificial intelligence in health care, from its role in automating clinical docume
From Clinical Notes to GPT-4: Dr. Emily Alsentzer on Natural Language Processing in Medicine
Dr. Emily Alsentzer (https://profiles.stanford.edu/emily-alsentzer) joins hosts Raj Manrai and Andy Beam on NEJM AI Grand Rounds to discuss the evolution of natural language processing (NLP) in medicine. A Stanford faculty member and expert
Health Care at the Breaking Point: Dr. Zak Kohane Returns to NEJM AI Grand Rounds
In this return appearance on NEJM AI Grand Rounds, Dr. Zak Kohane (https://dbmi.hms.harvard.edu/people/isaac-kohane) joins hosts Raj Manrai and Andy Beam to discuss the evolving landscape of AI in medicine. As the first repeat guest on the
The Economics of AI: A Conversation with Larry Summers
In this episode of NEJM AI Grand Rounds, hosts Raj Manrai and Andy Beam interview Larry Summers (https://larrysummers.com/) about artificial intelligence’s transformative potential and its implications for society. The conversation explores
Partners in Diagnosis: ChatGPT, a Mother’s Intuition, and a Doctor’s Expertise with Courtney Hofmann and Dr. Holly Gilmer
In this episode of NEJM AI Grand Rounds, hosts Raj Manrai and Andy Beam interview Courtney Hofmann (https://mcdn.podbean.com/mf/web/mheebcnd7tznbm5q/Bio_Morales_Hofmann.pdf), a mother whose use of ChatGPT led to her son’s diagnosis of tethe
The Pulse of Progress: AI in Cardiology with Dr. David Ouyang
In this episode of NEJM AI Grand Rounds, hosts Raj Manrai and Andy Beam interview Dr. David Ouyang (https://researchers.cedars-sinai.edu/David.Ouyang), a cardiologist and AI researcher at Cedars-Sinai Medical Center. The conversation explor
AI at the Frontlines: Dissecting Clalit’s Roadmap for the Future of Public Health with Noa Dagan and Ran Balicer
In this episode of NEJM AI Grand Rounds, hosts Raj Manrai and Andy Beam interview Dr. Noa Dagan and Dr. Ran Balicer from the Clalit Research Institute in Israel. The conversation explores Clalit’s groundbreaking work in implementing predict
From Petri Dishes to Pitch Decks: Cultivating Health Care’s AI Future with Vijay Pande
In this episode of NEJM AI Grand Rounds, hosts Raj Manrai and Andy Beam interview Dr. Vijay Pande, a general partner at Andreessen Horowitz (A16Z) where he leads investments in health care and life sciences. The conversation explores Pande’
Love and Large Language Models: Voices of the Future with Dr. Rohaid Ali and Dr. Fatima Mirza
In this episode of NEJM AI Grand Rounds, hosts Raj Manrai and Andy Beam interview Dr. Rohaid Ali (https://brownneurosurgery.com/our-team/rohaid-ali/) and Dr. Fatima Mirza (https://dermatology.med.brown.edu/people/fatima-mirza-md), a married
AI and the Evolution of Medical Thought with Dr. Adam Rodman
In this episode of the AI Grand Rounds podcast, Dr. Adam Rodman (https://cmecatalog.hms.harvard.edu/faculty-staff/adam-rodman) shares his unique journey from a historian to a physician deeply interested in the intersection of medicine and a
Translational AI in Medicine: Unlocking AI’s Potential in Health Care with Nigam Shah
In this episode of the NEJM AI Grand Rounds podcast, Dr. Nigam Shah (https://profiles.stanford.edu/nigam-shah), a distinguished Professor of Medicine at Stanford University and inaugural Chief Data Scientist for Stanford Health Care, shares
