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Pioneers of AI is your guide to the latest technological frontier. Each week, host Rana el Kaliouby (AI scientist, investor, author, co-founder of Affectiva) is joined by the leading creators, critics, and thinkers behind mind-blowing technology and asks the important questions about how artificial intelligence is changing the way we live. As we venture together into the unknown, Pioneers is your tool to understanding and anticipating what comes next.
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Are we ready for brain-computer implants?
The world of brain-computer interfaces, or BCIs, is here. Implanted into the brain, BCIs can pick up neural signals for all kinds of use cases – turning thoughts into words without speaking or typing, or even sharing thoughts with third par
Reid Hoffman and OpenAI CFO Sarah Friar on where AI goes from here
Few companies have as much influence over AI’s trajectory as OpenAI. Reid Hoffman sits down with CFO Sarah Friar to understand the precipice of the moment we are in and the decisions that could shape what comes next for each of us. This con
Replay: What my kids taught me about the AI divide
It often feels like the world is divided when it comes to AI — do you lean in, or opt out? But what if that tension exists within your own household? This week, we're reprising a candid conversation between host Rana el Kaliouby and her two
Is AGI already here? w/ Kevin Roose
Journalist Kevin Roose has closely watched and written about the AI race for about a decade, and his new book “The AGI Chronicles” documents the handful of driven people at the center of OpenAI, Google Deepmind, and Anthropic – along with t
OpenAI’s Tibo Sottiaux doesn’t want humans to be an ‘afterthought’
Thibault “Tibo” Sottiaux is OpenAI’s head of Product & Platform, making him responsible for the AI tools used by more than a billion users worldwide. Host Rana el Kaliouby spoke with Tibo about why he’s “proud” OpenAI delayed its latest Ast
Possible: Training robots for a world they've never seen
On this week’s episode we’re excited to share an episode from our sister podcast Possible, a podcast that sketches out the brightest vision of the future. Useful robots won’t be programmed one task at a time; they’ll need to adapt to unfami
The slippery slope of artificial intimacy
For the past four decades Sherry Turkle has studied the social and psychological implications of AI. She’s the Abby Rockefeller Mauzé Professor of the Social Studies of Science and Technology at MIT, founding director of the MIT Initiative
The ROI on AI is obvious in these industries
Rudina Seseri is the Founder and Managing Partner of Glasswing Ventures, recently named one of America’s Top Venture Capital Firms of 2026 by TIME and Statista. With a focus on early-stage AI-powered companies, Rudina has been investing in
Rapid Response: When AI agents do your shopping, everything changes, with Shopify’s Jess Hertz
For decades, e-commerce rewarded the biggest brands that could buy their way to the top of search results. AI is changing that. Shopify COO Jess Hertz joins Rapid Response to share what Shopify's data reveals about the agentic shopping revo
Zapier wants to be the AI hub where all your agents connect
Fifteen years ago Wade Foster, CEO of Zapier, co-founded the software company with a simple idea: link thousands of apps that were never designed to talk to each other, so people could work seamlessly between them. Now, he's turning Zapier
Axios’ Ina Fried reads the AI fine print, so you don’t have to
In the world of AI, data is king. And in reporting on tech for nearly 30 years, Axios’ Chief Technology Correspondent Ina Fried has extensively covered concerns around consumer data, privacy, and Big Tech. In the latest edition of her long-
Rapid Response: What the jobs report isn't telling you about AI & the workforce, with Upwork’s Hayden Brown
Few leaders have a better real-time read on how AI is actually reshaping the workforce than Hayden Brown. As CEO of Upwork, the platform where 18 million freelancers meet the businesses that need them, she sees what the monthly jobs report
Government benefits are broken. Is AI the fix?
Stories of people standing in line for hours to get their drivers license or being wrongfully denied government food assistance are common in America. Few people think, “I can solve this problem.” But the CEO of Promise, Phaedra Ellis-Lamki
World Models: a trillion dollar opportunity
In the first half of 2026 alone, investors poured $3 billion into the next frontier of AI: World Models. Google DeepMind, Fei-Fei Li’s World Labs, Yann LeCunn’s AMI labs, and Odyssey are all building in this space. In this episode, host Ran
Rapid Response: OpenAI’s Critterz blowback — Director Nik Kleverov on year zero for Hollywood
Critterz was one of the first feature films built primarily with AI, but OpenAI abruptly shut down Sora, the very tool its director was relying on. Nik Kleverov, Chief Creative Officer of Native Foreign, joins Rapid Response from the Cannes
Replay: Could a robot fix the loneliness epidemic?
This week we reprise our episode with robotics developer Grace Brown, co-founder and CEO of Andromeda, an Australia- and US-based company. A recently launched study (https://health.ucdavis.edu/news/headlines/uc-davis-launches-first-long-ter
The deep AI shifts that will reshape our lives
For nearly two decades, Amy Webb's annual Tech Trends Report was required reading for anyone trying to keep up with technology. But this year, Webb killed the report and replaced it with something more applicable for leaders in an AI era. I
Why AI conversations are always one-sided
Is it possible for us to ever wholeheartedly trust a machine the way we would a human? According to Charles Duhigg, Pulitzer Prize-winning journalist and New York Times bestselling author of The Power of Habit and Supercommunicators: How to
Rapid Response: The quiet reinvention of a $42b business, with Canva’s Cameron Adams
In the last year, Canva redefined itself from the ground up. Co-founder and Chief Product Officer Cameron Adams joins Rapid Response live from the Cannes Lions festival to explain why the so-called SaaSpocalypse never kept him up at night,
WorkLab: Culture, not tech, softens AI’s impact
AI's promise is real. But the challenge to realizing its value isn't technology—it's people. Rana el Kaliouby joins WorkLab's Molly Wood to explore what can stall progress. The conversation explores how emotional intelligence, empathy, and
Stanford’s Silicon Valley pipeline, investigated
American universities are a critical pillar of US innovation. But what happens when Silicon Valley gets more intentional about that, treating a campus more like a talent pipeline, especially in the race to build AI? In his new New York Time
What my kids taught me about the AI divide
It often feels like the world is divided when it comes to AI — do you lean in, or opt out?. But what if that tension exists within your own household? In this episode, Rana brings her kids onto the show for a candid conversation about AI ad
AI on the pitch at The World Cup
At the 2026 FIFA World Cup, AI has already played a role in high stakes moments – revealing “just barely” violations that have broken hearts and driven hopes for millions of fans. As the tournament’s technology partner, Lenovo has augmented
Masters of Scale: IBM’s $10 billion bet on what comes after AI
While many tech companies race to build ever-larger AI models, IBM CEO Arvind Krishna sees the future differently. Speaking with host Bob Safian before a live audience during New York Tech Week, Krishna explains why enterprises are overcomp
Reid Hoffman says the AI race is not a cage match
Anthropic and OpenAI’s plans to go public have set off waves of speculation about the ripple effects, and how they’ll stack up to the SpaceX IPO. What’s really driving the value of these companies? Does the timing of the IPOs matter? How mi
What we risk losing to AI, w/ Natalie Monbiot
Natalie Monbiot is the founder of Virtual Human Economy (VHE) and was one of the first experts to advocate that your digital twin can be one of your most valuable assets. In fact, she argues that when we use AI models like ChatGPT and Claud
Rapid Response: The race no one can win: AI’s anti-human crisis, with Aza Raskin
Big Tech is moving fast on AI. But who's watching out for the rest of us? Aza Raskin, co-founder of the Center for Humane Technology, has spent years sounding the alarm about where the race to build powerful AI is actually taking us. He joi
Does AI know you better than your doctor? w/ Ōura CEO Tom Hale
Historically, the only way to know what was going on in your body was to make a doctor’s appointment, run tests, and wait for the results. Now, wearable tech is changing access to health data. Rana sits down with Tom Hale, CEO of Ōura, the
Reimagining business school through AI with MasterClass CEO David Rogier
When MasterClass (https://www.masterclass.com/) CEO David Rogier was a kid, his grandmother sat him down and told him how she'd lost everything during World War II. The lesson David took from her is that education is the one thing no one ca
Rapid Response: Duolingo’s battle for learning in an AI world, with Luis von Ahn
When Duolingo CEO Luis von Ahn sent an internal memo about AI last year, he didn't expect it to go viral — or to ignite a firestorm about the future of work. Now he joins Rapid Response to unpack what he got right, what he got wrong, and wh
