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Possible with Reid Hoffman

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  1. Should we give AI a bank account?

    In this episode of Possible, Reid Hoffman and Aria Finger talk with Sean Neville, co-founder of Circle and architect of USDC, about building the financial infrastructure for an AI-driven economy. Now leading Catena Labs, Neville is working

  2. After SaaS

    Is SaaS actually dead or just evolving? Reid and Aria break down why the traditional seat-based software model is under pressure as AI reshapes how products are built, priced, and delivered. They discuss how these fundamental changes have s

  3. Humans secretly prefer AI writing

    Reid and Aria unpack three emerging fault lines in the AI era: where real power sits in the AI stack, how AI is reshaping human creativity, and whether governments could ultimately treat AI as critical national infrastructure. Reid responds

  4. The AI Kept Choosing War

    Reid and Aria unpack new research on AI decision-making in simulated nuclear crises—and what it reveals about the limits of machine reasoning. They explore why frontier models consistently escalated to nuclear conflict in war game scenarios

  5. How Notion rebuilt for the age of AI

    In this episode of Possible, Reid and Aria talk with Ivan Zhao, co-founder of Notion, about what happens when intelligence becomes abundant rather than scarce. Zhao shares his philosophy of treating computing as a material — like steel or s

  6. Network effects, AI medicine, and the fight for free speech

    In this episode, Reid and Aria are live from New York as they unpack why predictions about the “death” of San Francisco and New York keep missing the mark and how network effects continue to anchor these cities as the world’s leading tech a

  7. Does AI really save time?

    In this episode, Reid and Aria examine a growing tension at the heart of the AI moment: whether these tools are actually saving time or simply accelerating the pace, volume, and expectations of work. The conversation touches on workflows ac

  8. Making sense of the layoff wave

    In this episode, Reid and Aria unpack the growing panic around layoffs, the actual impact of AI on work, and why autonomous agents are reshaping productivity faster than most people realize. Reid points out that today’s layoffs are being er

  9. CryptoPunks creators: from art experiment to cultural movement

    Before NFTs were a category and crypto was an industry, two artists released 10,000 characters into the world with no roadmap, no pitch, and no expectations. What started as an art experiment in code ended up flourishing into a movement abo

  10. Reid Riffs with Parth Patil on AI-Native Startups (Part 3 of 3)

    This episode is our third and final installment of a special, three-part Reid Riffs miniseries focused on what it actually means to become AI-native. In this episode, Parth shares how founders can rethink work by breaking problems into modu

  11. Reid Riffs with Parth Patil on Enterprise AI Integration (Part 2 of 3)

    This episode is our second installment of a special, three-part Reid Riffs miniseries focused on what it actually means to become AI-native. Instead of a news or headline-driven conversation, Reid sits down one-on-one with AI engineer and s

  12. Reid Riffs with Parth Patil on Individual AI Mastery (Part 1 of 3)

    This is the first of a special, three-part Reid Riffs miniseries. Instead of a news-and-headline driven conversation, Reid sits down one-on-one with Parth Patil, an AI engineer and strategist, for a deeper exploration of what it actually me

  13. Amjad Masad on vibe coding, AI agents, and the end of boilerplate

    On this episode of Possible, Reid Hoffman and Aria Finger sit down with Amjad Masad, founder and CEO of Replit, to explore how AI is fundamentally changing who gets to build software and what that means for work, creativity, and human agenc

  14. BONUS: Conversations with Coleman: Big Tech, Politics, and Trust in Institutions

    This is a bonus episode from the Conversations of Coleman podcast, featuring Reid Hoffman as the guest. Here are the show notes from that episode: My guest today is entrepreneur and LinkedIn co-founder Reid Hoffman. He’s now facing somethin

  15. Stephen Colbert on connection, discovery, and human nature

    This is a holiday special re-airing of our excellent episode with Stephen Colbert. What could we gain—and what might we lose—when technology begins to approximate the contours of human connection and presence? In this episode, Reid and Aria

  16. The power of AI, from curing cancer to ballot boxes

    In this special episode of Reid Riffs, Reid and Aria are joined by Pulitzer Prize–winning author, oncologist, and Manas AI cofounder Siddhartha Mukherjee for a few questions about cancer, AI, and the second edition of The Emperor of All Mal

  17. The AI energy war is here

    In this episode of Reid Riffs, Reid and Aria explain why "compute" is the new oil powering the cognitive industrial revolution. They argue that the United States must urgently expand domestic data centers and energy infrastructure to remain

  18. R.I.P. Computer Keyboard (1964 – 2025)

    In this special live episode of Possible, Reid and Aria sit down with Wispr Flow founder and CEO Tanay Kothari to explore a post-keyboard future where voice becomes the primary way humans interact with computers. From building one of the wo

  19. AI’s Influence On The Church, Cybersecurity, and Disney

    This week, Reid and Aria dive into three central AI stories that have been dominating the headlines: Pope Leo XIV issues a powerful call for moral discernment in an AI-driven world, Anthropic reveals that state-sponsored hackers used agenti

  20. Our AI blindspot: incentives over intentions

    Software is eating the world, but will it start eating us? On this episode of Possible, Aria Finger and Reid Hoffman sit down for an encore conversation with Aza Raskin that dives deep into how AI and engagement-driven tech are reshaping ou

  21. How we regulate AI could decide the next century

    In this episode of Possible, Reid Hoffman and Aria Finger explore how AI is colliding with real-world regulation, responsibility, and even civility. As states like Utah, California, and Illinois roll out new AI laws governing everything fro

  22. Reid riffs on NVIDIA's chips, China’s AI ambitions, and the push to pause AI

    This week Reid and Aria break down the global AI race from Nvidia’s $5 trillion valuation and the U.S.–China chip rivalry to what happens when AI starts reshaping industries like medicine. Reid explains why the future of innovation depends

  23. Steve Kerr and Kris Brown on Leadership, Purpose, and Innovation in Sport and Society

    What does it take to turn tragedy into advocacy, and advocacy into lasting change? This week, Reid and Aria are talking to Warriors head coach Steve Kerr and Kris Brown, president of Brady, the nation’s oldest gun violence prevention organi

  24. Aza Raskin on interspecies communication, empathy, and AI’s next frontier

    Can AI help us better understand animals and, if it could, what might we discover? This week’s episode was recorded live at the 2025 Masters of Scale Summit where Reid and Aria sat down with Aza Raskin, co-founder and CEO of the Earth Speci

  25. Reid riffs on fostering trust with founders, in boardrooms, and in AI

    In this week's episode, Reid and Aria unpack why trust is a practical skill, not just a feeling. Reid riffs on the importance of hands-on investor-founder relationships, boardroom decisions that can make or break a company, and investor beh

  26. David Fajgenbaum on drug repurposing, AI, and saving his own life

    How can AI really help advance medicine? Should patients and care teams be seeking second opinions from LLMs? This week, Reid and Aria sit down with physician-scientist Dr. David Fajgenbaum, who repurposes existing drugs to save lives—inclu

  27. Reid riffs on Trump’s $100K visa fee, 3-day work weeks, and AI trust issues

    This week, Reid and Aria dive into the debate over new $100,000 fees on H-1B visas, and discuss how immigration powers U.S. innovation and how to ensure startups aren’t shut out. They also cover developers’ mixed feelings about using AI in

  28. Lisa Su on semiconductors, compute, and big bets

    What’s the role of semiconductors—and the companies that make them—in powering human progress? What does it look like to innovate thoughtfully in a landscape where the demand for power may be higher than the supply? With AI evolving faster

  29. Reid Riffs on AI translations, Apple Intelligence, and OpenAI’s Critterz

    This week, Reid and Aria discuss Apple’s new AirPods Pro 3 and live translation capabilities, AI-generated movies (specifically Critterz from OpenAI), and what really could be lost — or gained — as AI technology becomes more widespread. Plu

  30. Stephen Colbert on connection, discovery and human nature

    What could we gain—and what might we lose—when technology begins to approximate the contours of human connection and presence? In this episode, Reid and Aria chat with comedian, actor, and political commentator Stephen Colbert. Best known f

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