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Making artificial intelligence practical, productive & accessible to everyone. Practical AI is a show in which technology professionals, business people, students, enthusiasts, and expert guests engage in lively discussions about Artificial Intelligence and related topics (Machine Learning, Deep Learning, Neural Networks, GANs, MLOps, AIOps, LLMs & more).
The focus is on productive implementations and real-world scenarios that are accessible to everyone. If you want to keep up with the latest advances in AI, while keeping one foot in the real world, then this is the show for you!
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Abundant Intelligence at the Midwest AI Summit
In this special episode, we bring you highlights from three talks at the Midwest AI Summit. Heidi Porter explores how to build reliable AI-augmented workflows using the right tools, evaluations, and guardrails. Kevin Solorio shares why buil
Exploit Development, Agentic Vulnerability Discovery, and Fake PoCs
AI is changing cybersecurity, accelerating vulnerability research and exploit development while raising new questions about reliability, risk, and guardrails. Daniel and Chris talk with Spencer McIntyre, Director of Exploit Development at V
Is Education Failing our Students in this AI-Driven World?
Schools and universities are failing to adapt to our modern world, in which AI is becoming increasingly pervasive in all aspects of life and work. In fact, AI may be changing what should be considered foundational knowledge that all student
Narrative intelligence and the human advantage
As AI reshapes how we work, create, and think about our roles, staying adaptable means understanding not just the technology, but our own stories and identities. Reed Frerichs joins Daniel and Chris to explore narrative intelligence, storyt
Open models and the future of Physical AI with NVIDIA
As AI moves beyond the cloud and into robots, vehicles, and other physical systems, new approaches to models, simulation, and inference are emerging. Daniel and Chris are joined by Ming-Yu Liu, Vice President of Cosmos Lab at NVIDIA, who sh
From AGENTS.md to Enterprise Deployment
AI agents are moving beyond laptops and prototypes and into enterprise environments where security, compliance, scalability, and reliability matter. Nick Kuhn from VMware Tanzu Platform joins Daniel and Chris to discuss what changes (and wh
How to get discovered in AI search
AI search is changing how people discover information and how brands need to think about visibility. Daniel and Chris talk with Liam Dunne and Ben Moore, co-founders of Discovered Labs, about the shift from traditional SEO to AI search, wha
Computer-Use Agents and the Future of the Agentic Internet
Longtime followers of Practical AI know that multi-repeat guest and friend Demetrios Brinkmann combines brilliant insight and playful banter into one fun-filled show, and this conversion with Chris was no different. They had a blast! As AI
Less about Models; More about Architecture
As AI moves from experimentation to enterprise deployment, are organizations thinking too much about models and not enough about architecture? In this episode, Daniel and Chris talk with Chetan Gupta, Chief AI Officer at Rackspace, about th
Building the Foundation for the Agentic AI Era
How do we build an AI ecosystem where agents, tools, and systems can work together at scale? Angie Jones, VP of the Agentic AI Foundation, joins Chris to discuss the open standards and projects shaping the agentic future, including MCP, A2A
AI Proficiency: From Users to Builders
As AI continues to reshape how organizations work, companies are increasingly asking what AI proficiency should look like across their workforce, and how they can help employees adapt without simply mandating AI adoption. Our returning gues
Models, Harnesses, and Multi-Agent Systems
AI has moved far beyond chatbots, but what exactly are AI models, agents, agent harnesses, and multi-agent systems, and why do they matter? In this episode, Daniel and Chris break down the terminology behind today's AI landscape, explain th
Reconstructing how OpenAI agents attacked Hugging Face
What happens when AI agents driven by a top frontier model escape their secure sandbox? Join Daniel and Chris as they unpack the AI wonk's equivalent of a murder mystery! OpenAI agents went rogue and successfully attacked Hugging Face priva
Surviving the New Economics of a Post-Agentic World
The agentic transformation isn’t coming. It has already begun. Companies are deploying thousands — and sometimes tens of thousands — of AI agents. Enterprise software giants are watching their old economic moats erode. Capital is moving, pr
The Future of AI Infrastructure with CoreWeave
As AI applications become more complex, the infrastructure powering them needs to evolve. Corey Sanders, SVP of Product at CoreWeave, joins Chris to discuss why AI requires a fundamentally different approach than traditional cloud computing
Building Durable AI Agents
What does it take to move AI agents from demos to reliable production systems? In this episode, Hamza Tahir explores how MLOps principles are shaping the future of generative AI, covering workflows, agent harnesses, fleets, and the infrastr
Image Generation and Visual Intelligence with Black Forest Labs
How has AI image generation evolved from blurry outputs to powerful visual intelligence models? Dustin Podell, Co-Founder and Researcher at Black Forest Labs, explains the progression from diffusion to flow matching, how modern image models
AIUC-1: Building trust in AI agents
How do we build trust in AI agents before the AI hailstorm arrives? Emil Lassen from the Artificial Intelligence Underwriting Company (AIUC) joins the show to discuss how the enterprise flywheel of standards, certification, audit, and insur
Zero Trust for AI Agents
As AI agents become more capable and autonomous, they also introduce new security challenges. In this 'Fully Connected' episode, Dan and Chris unpack Anthropic’s Zero Trust for AI Agents security framework and what it means for organization
Breaking down the 2026 Stanford AI Index Report
AI models can win math olympiads… but still struggle to read an analog clock. In this fully connected episode, Dan and Chris break down the latest Stanford AI Index Report and explore what it reveals about the current state of AI. They disc
Rebooting Enterprise AI with MCP and Kubernetes
What happens when AI agents start acting less like chatbots and more like coworkers? In this episode, Dan and Chris sit down with Craig McLuckie, CEO of Stacklok to explore MCP, Kubernetes, ToolHive, enterprise AI, and the emerging infrastr
Hermes Agent: Agents that grow with you
Open Source AI is entering a new era, one shaped by self-improving AI Agents, recursive learning systems, and rapidly evolving AI Tools that blur the line between software and autonomous collaborators. In this episode, Daniel and Chris sit
U.S. Congressman Beyer on AI challenges facing America and the World
U.S. Congressman Don Beyer returns to Practical AI for another far-reaching conversation with Chris about many of the most important AI challenges facing America and the world. Blending political savvy and statesmanship with his unique tech
The Myth of Model Wars: Open vs Closed AI in 2026
In this fully connected episode, Dan and Chris break down one of the biggest questions in AI today: do open vs. closed models still matter? From the rise of physical AI and edge devices to the shifting landscape of open-source models like L
The mythos of Mythos and Allbirds takes flight to the neocloud
In this Fully-Connected episode, Dan and Chris start with Anthropic's Mythos frontier model, parsing what is publicly known about its cybersecurity capabilities and projecting its possible implications from "We've been here before. 🙄" to "
Open Source Self-Driving with Comma AI
Autonomous driving is not just a big tech or closed-source game, it's becoming accessible through open innovation and real-world deployment. Dan and Chris sit down with Harald Schäfer, CTO at Comma AI, to explore how OpenPilot is bringing s
Post-Mortem of Anthropic's Claude Code Leak
In this fully connected episode, Dan and Chris break down the Anthropic Claude Code leak, what went wrong and what it reveals about agentic systems, AI architecture, and AI safety. They also explore how the open source community is respondi
Agentic Coding and the Economics of Open Source
AI is rapidly transforming how software is built, shifting economic incentives from open source code and collaboration toward on-demand, personalized development through agentic coding a.k.a. vibe coding. In this episode, Chris speaks with
AI at the Edge is a different operating environment
What does “AI at the edge” really mean in 2026, and why does it matter now more than ever before? In this episode, we’re joined by Brandon Shibley, Edge AI Solutions Engineering Lead at Qualcomm’s Edge Impulse, to discuss the current state
Humility in the Age of Agentic Coding
What happens when an AI hater starts building with AI agents? In this episode, we talk with software engineer Steve Klabnik, known for his work on the Rust programming language, about his journey from criticizing AI to experimenting with it
