Ondansetron for Negative Symptoms of Schizophrenia

In this episode, we examine a surprising repurposing of ondansetron — a common antiemetic — as a potential adjunctive treatment for the notoriously hard-to-treat negative symptoms of schizophrenia. Could a nausea medication help restore motivation and emotional engagement in your patients with residual symptoms despite stable antipsychotic therapy?
Faculty: Oliver Freudenreich, M.D. Host: Richard Seeber, M.D.
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• Is Ondansetron Effective for Negative Symptoms in Schizophrenia?