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Psychopharmacology and Psychiatry Updates

Trazodone for Insomnia and Comorbid Depression

Montag, 28. September 2026 · 11 min

MP3

Shownotes

In this episode, we explore a new meta-analysis reconciling trazodone's real-world reputation with cautious sleep medicine guidelines, examining its effects on sleep architecture and depressive symptoms in patients with comorbid insomnia and depression, alongside its notable side effect profile. Can a decades-old antidepressant be the missing link for restorative sleep?
Faculty: Paul Zarkowski, M.D. Host: Flavio Guzmán, M.D.
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• Trazodone for Insomnia and Comorbid Depression: Are the AASM Guidelines Relevant?

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