Psychopharmacology and Psychiatry Updates
Trazodone vs. Doxepin vs. Melatonin: Comparing Alternatives for Sleep
Freitag, 7. November 2025 · 11 min
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Shownotes
In this episode, we explore a head-to-head comparison of trazodone, doxepin, and melatonin for treating insomnia when benzodiazepines are off the table. Which non-benzodiazepine sleep aid offers the best balance of effectiveness and tolerability in real-world psychiatric patients?
Faculty: Paul Zarkowski, M.D. Host: Richard Seeber, M.D.
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• Melatonin, Trazodone, or Doxepin for Sleep Disorders