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980: AI Making Theoretical Physics Breakthroughs
A team of theoretical physicists from Harvard, Cambridge, the Institute for Advanced Study, and Vanderbilt used OpenAI’s models not just as a tool, but as a collaborator, cracking a problem in particle physics that had stymied them for mont
979: Agentic Data Management and the Future of Enterprise AI, with Rohit Choudhary
For years, Jon has been quoting the stat that the world's data is roughly doubling every year. His guest today says that’s way too conservative, he’s seeing enterprise data soon growing at close to 10x per year. And most organizations are n
978: A Post-Transformer Architecture Crushes Sudoku (Transformers Solve ~0%)
A game millions of people solve over morning coffee is exposing a fundamental weakness in today’s most powerful AI models. In this Five-Minute Friday, Jon Krohn breaks down Pathway’s new Sudoku Extreme benchmark, roughly 250,000 of the hard
977: Attention, World Models and the Future of AI, with Prof. Kyunghyun Cho
What’s going to be the next big step function that blasts us forward in AI capabilities? To find out, Jon Krohn sits down with Professor Kyunghyun Cho, whose 200,000 citations and co-authorship of the first paper on attention place him amon
976: NVIDIA’s Nemotron 3 Super: The Perfect LLM for Multi-Agent Systems
NVIDIA just dropped Nemotron 3 Super, a 120-billion-parameter open-weight model that only activates 12 billion parameters at a time and it’s built for the agentic AI era. In this Five-Minute Friday, Jon Krohn breaks down the model’s hybrid
975: Unmetered Intelligence is Heralding the Next Renaissance, with Zack Kass
Zack Kass speaks to Jon Krohn about his bestselling, tech-positive book, The Next Renaissance, that charts the rapid progress of humanity and the benefits that artificial intelligence will bring to us, as well as why a future where intellig
974: When Will The AI Bubble Burst? How Bad Will It Be?
In this week’s Five-Minute Friday, Jon Krohn holds the AI bubble up to the light. He points to the deep greyzone found in AI startups like Cluely that are established on dubious ideas (Cluely’s tagline was “cheat on everything”) and funding
973: AI Systems Performance Engineering, with Chris Fregly
No one should be manually writing code in 2026, thinks Chris Fregly, Jon Krohn’s guest on this week’s episode. In this interview about Chris’ latest book, AI Systems Performance Engineering, he explains why it’s so important to consider mem
972: In Case You Missed It in February 2026
Jon Krohn recaps the month of February in this episode of In Case You Missed It. Across four interviews with Will Falcon (Episode 965), Tom Griffiths (Episode 969), Antje Barth (Episode 963), and Praveen Murugesan (Episode 967), Jon questio
971: 90% of The World’s Data is Private; Lin Qiao’s Fireworks AI is Unlocking It
Lin Qiao, CEO of Fireworks AI, talks to Jon Krohn about how she builds effective models quickly, why coding agents can perform at the level of a junior engineer, and what she attributes to the success of Fireworks AI: True to its name, the
970: The “100x Engineer”: How to Be One, But Should You?
Working with code-gen models and Claude Code: In this Five-Minute Friday, Jon Krohn addresses how AI superstars like Andrej Karpathy are using AI agents in their coding work, the outlook for code-gen in 2026, and how you can get started. He
969: The Laws of Thought: The Math of Minds and Machines, with Prof. Tom Griffiths
Princeton Professor Tom Griffiths talks to Jon Krohn about his new book, The Laws of Thought, which grapples with the mathematical models behind biological and artificial intelligence, and what makes the human brain so fascinating for psych
968: Is AI Automating Away All Coding Jobs?
Now that AI agents can develop new apps from product development to delivery, do AI developers have reason to worry about their careers? Podcast host Jon Krohn addresses the stark predictions that AI could “eliminate half of all entry-level
967: AI for the Physical World, with Samsara's Praveen Murugesan
VP of Engineering at Samsara Praveen Murugesan talks to Jon Krohn about processing 20 trillion data points covering 90 billion miles across private and public sectors, how the company helps truckers who operate long hours and travel for lon
966: The Moltbook Phenomenon: OpenClaw Unleashed
Jon Krohn gives Five-Minute Friday listeners all the details about the new social network causing a stir, Moltbook. What makes Moltbook so unique is that this is the first network designed just for AI agents. It’s an exclusive club, only it
965: From PhD Side Project to $500M ARR: Will Falcon’s PyTorch Lightning Story
CEO of Lightning AI Will Falcon speaks to podcast host and Lightning AI fellow Jon Krohn about the company’s merger with Voltage Park, and why Will has named it the “full-stack AI neo-cloud for enterprises and frontier labs”. Lightning AI’s
964: In Case You Missed It in January 2026
In this first of the year ICYMI episode, Jon Krohn selects his favorite moments from January’s SuperDataScience interviews. Listen to why incentivizing workers is the best way to get them to disclose their use of AI tools and pave the way f
963: Reinforcement Learning for Agents, with Amazon AGI Labs’ Antje Barth
Bestselling author and Gen AI instructor Antje Barth talks to Jon Krohn about her work at Amazon’s AGI Labs and their newest product Nova Act, as well as where we will see the most success with AI agents and how AI developers can reap those
962: Wharton Prof Ethan Mollick on Why Your AI Strategy Is Already Obsolete
Bestselling author of Co-Intelligence: Living and Working with AI Ethan Mollick speaks to Jon Krohn about just how much US firms have to gain from a willingness to adopt and experiment with AI, as well as the reality behind AI use among emp
961: Distributed Artificial Superintelligence, with Dr. Vijoy Pandey
Dr. Vijoy Pandey returns to the show to talk to Jon Krohn about Cisco’s work to advance medicine and mitigate the impact of climate change with distributed artificial super-intelligence. Dr. Vijoy Pandey believes in a future where humans an
960: In Case You Missed It in December 2025
For 2026’s first episode of In Case You Missed It (ICYMI), Jon Krohn selects 6 clips from December for a wide-ranging look at the current state of AI in business and beyond. Hear from Joel Beasley (Episode 945), Jeff Li (Episode 947), Sandy
959: Building Agents 101: Design Patterns, Evals and Optimization (with Sinan Ozdemir)
AI entrepreneur and bestselling author Sinan Ozdemir speaks to Jon Krohn about the practical differences between agentic AI and AI workflows, why evaluating accuracy on its own won’t tell you enough about AI models, and more about his lates
958: Without Trusted Context, Agents are Stupid (featuring Salesforce’s Rahul Auradkar)
In this #sponsored Feature Friday episode, Salesforce’s Rahul Auradkar speaks to Jon Krohn about the company’s unified data engine and how its acquisition of Informatica provides the missing context layer for AI models and agents. Hear how
957: How AI Agents Are Automating Enterprise Data Operations, with Ashwin Rajeeva
AI agents, data lakes, and managing data sprawl: Ashwin Rajeeva, cofounder and CTO of Acceldata, speaks to Jon Krohn about how the agentic data management startup raised over $100 million in venture capital to expand its business in automat
956: From Agent Demo to Enterprise Product (with Ease!) feat. Salesforce’s Tyler Carlson
#Sponsored SVP, Head of Product for Salesforce’s AppExchange & Ecosystem, Tyler Carlson, talks to Jon Krohn about taking AI agents from prototype to enterprise-grade production with the Agentforce 360 Platform. Though we may now have plenty
955: Nested Learning, Spatial Intelligence and the AI Trends of 2026, with Sadie St. Lawrence
Sadie St Lawrence joins Jon Krohn to discuss what to expect from the AI industry in 2026. Sadie and Jon talk through what they think will be the five biggest trends in AI, hand out awards for the best moments, comebacks, and disappointments
954: Recap of 2025 and Wishing You a Wonderful 2026
Jon Krohn wraps up 2025 with his thoughts on how agentic AI has become as much a resounding success as an annoying buzzword for many in the tech industry, why such promising developments in generative AI mean that well-prepared, secured dat
953: Beyond “Agent Washing”: AI Systems That Actually Deliver ROI, with Dell’s Global CTO John Roese
Dell Technologies’ John Roese talks to Jon Krohn about the phenomenon of “agent-washing”, his contribution to Dell’s incredible revenue boost in 2025, and why “knowledge layers” will be crucial to future tech. Hear also John’s predictions f
952: How to Avoid Burnout and Get Promoted, with “The Fit Data Scientist” Penelope Lafeuille
“The Fit Data Scientist” newsletter author Pénélope Lafeuille talks to Jon Krohn about how to give your all at work, offering her top tips for a healthy body and a healthy mind. Learn why “The SuperDataScience Podcast” made it onto her top
951: Context Engineering, Multiplayer AI and Effective Search, with Dropbox’s Josh Clemm
VP of Engineering at Dropbox Josh Clemm speaks to Jon Krohn about consolidating search tools across apps with the AI-powered workspace, Dropbox Dash, the new collaborative AI systems that enhance interoperability between team members and th
