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The New Face of Anti-Ag Pseudoscience - Vance Crowe
In this conversation, Dr. Kevin Folta and Vance Crowe discuss the evolving landscape of agriculture communication, the rise of pseudoscience, and the cultural shifts affecting public trust in science. Vance shares his journey from working a
Biotech Enhancement of Protein in World Staple Crops - Dr. Ling Li
Protein is essential for normal human development and physiology, yet is a significant global deficiency. World food staple crops like rice, wheat, cassava, and potato have relatively protein levels, yet constitute a significant portion of
The GMO Tree You Never Heard About - Dr. Chris Dardick, USDA/ARS
We regularly discuss a small suite of commercial crops that have been genetically enhanced with transgenes. However, one additional genotype was transformed long ago, and approved for use in the USA, Canada and EU-- but nobody talks about i
Anti-GMO Hawaii Memories; A Career in Ag Science - Dr. Steve Savage
In 2013 a number of county ordinances sought to end the use of biotech crops on various Hawaiian islands. Hawaii's warm year-'round climate permits several corn seasons a year, so seed corn for the mainland is produced in these locations. H
Enabling Local Production of Protein Therapeutics - Dr. Kerry Love, Sunflower Therapeutics
Great products and ideas are everywhere, yet limited by the ability to actually produce them in needed quantitites. The technologies from Sunflower Therapeutics enable bioprocess applications throughout the globe in a deployable unit with a
Measuring the Health of T-Cells - Dr. Nigel McCracken, Virax Biolabs
T-cells are a critical part of the adaptive immune system, actively targeting problematic invaders. From pathogens to cancers, T-cells seek and destroy potentially dangerous cells, and maintain a memory of their presence. In today's episode
Resistance to Correction, Breaking Trust in Science - Drs. Andrea Love and Nicole Keller
Disinformation clouds the public understanding of science, especially technology in agriculture and medicine. So when a leading journal publishes false information, academic experts have an obligation to help correct the process. This may b
Your Role in Editing Wikipedia - Susan Gerbic
Wikipedia is the go-to source for many people when starting to research a subject. But is the information correct, or does the information even exist in Wikipedia at all? Susan Gerbic has been training people to edit Wikipedia pages through
Gene Editing in Specialty Crops - Dr. Tom Adams, CEO Pairwise
Crop genetic engineering has focused primarily on large-acreage crops like corn. But what about the universe of specialty crops that tantalize consumers, things like blackberries or salad greens? Pairwise has used precision twists on gene e
Special Panel - From Pre-Clinical to Clinical Trials
Advancement of a new drug from pre-clinical trials to clinical trials is a pivotal time in validation of its therapeutic effects and safety. A panel of experts discusses the process.
Talking Biotech Begins Year 10! with Dr. Liza Dunn
Today's episode marks the beginning of the 10th year of the Talking Biotech Podcast. To celebrate, Drs. Liza Dunn and Kevin Folta discuss the last decade of biotech breakthroughs and communications efforts, the fight against technology and
Targeting Chronic Inflammation Via the Inflamasome - Dr. David Bearss
Chronic inflammation goes hand-in-hand with many diseases, complicating symptoms and affecting routes of treatment. What is the molecular basis of inflammation, and can it be targeted by new drugs? Scientists have studied the molecular basi
Development of Biotech Partnerships
Strategic partnerships are becoming more important in development and deployment of biotechnology solutions. Today's panel discusses the way partnerships are formed, some of the important considerations with IP and licensing, and how relati
Journal Club - Were "High Levels" of Glyphosate Found in Sperm? - Dr. Andrea Love
The news reports say that scientists have found "high levels" of herbicide in human sperm, and suggest it is a cause of infertility. But what do the data really say? Dr. Andrea Love and I discuss the paper. A report by Vasseur et a (https:/
Standardizing Therapeutic Protein Production in Plants - Jim Wilson
Where many therapeutic compounds are raised in bacteria or fungi, plants sometimes offer many advantages as bioreactors. Capital and production costs are lower, and products may be edible instead of injectable. The problem tends to be stand
Canadian Rules for Gene Editing - Jennifer Hubert
Canada has a unique approach to plant genetic improvement that follows the product, not the process. In other words, if there is potential risk from any genetic manipulation technique, from polyploidization to transgenic to gene edits, Cana
Overcoming CAR-T Cell Bottlenecks - Dr. Andy Scharenberg
Immunotherapy is weaponizing the body's immune system against cancer or other disease. One of the most promising approaches is CAR-T cell therapy, yet as this technology has been implemented, it's limitations have been identified. Dr. Andy
The FDA Regulatory Ecosystem- Expert Panel Discusses the Process
How do new drug applications move forward to approval? Four experts discuss the partnership between the FDA, the drug developer, and the data needed to move a product forward. It is a surprising discussion that reveals the depth of the FDA
The Psychology of Risk - Dr. Felicia Wu
We live in amazing times of technological advance, but how are the real benefits of new tech lost to an inflated sense of risk? Dr. Felicia Wu from Michigan State University shares her expertise in describing the psychological basis of risk
Restoring the Forest with GE American Chestnut - Dr. Andy Newhouse and Erik Carlson
This is an update on the American Chestnut Restoration Project, as discussed previously on the podcast. The American Chestnut dominated the forests of Appalachia until an imported fungus destroyed the entire range. Efforts to restore the ch
Addressing Disparities in Women's Healthcare - Sabrina Johnson, CEO Daré Bioscience
Despite being over half of the population women's health care lags behind other areas of drug development. The problem is caused by many facets, but is augmented by the fact that many of the conditions are not life threatening or are functi
Return of Talking Biotech; Stories in the News
After a three month hiatus the Talking Biotech Podcast is back. Today's episode is a visit with Colarbra CEO Aoi Senju about his view for the podcast, followed by synopsis of three major news stories that broke since the last Talking Biotec
Temporary Hiatus, Changes Coming!
After 8.5 years of weekly podcasts I'm going to take a 5 week break and plan new episodes for 2024. I'm going through a medical glitch that has me unable to do my normal work. On top of this we're going to switch to an audio plus video form
A Novel RNAi Approach to Crop Protection - Todd Hauser
Even under the best conditions, crops need our assistance to survive the numerous threats that limit production. Classically, synthetic and natural compounds have been used to control insects, fungi and weeds, sometimes with negative collat
Drugs from the Rainforest - Lisa Conte
There is tremendous variation in the plant kingdom, as plants have adapted to many ecological niches with discrete challenges. Part of adaptation is production of novel secondary metabolites, compounds not required for central metabolism th
Proposed Gene Editing Changes in the EU -Dr. Emma Kovak
Gene editing is a powerful and specific technique that allows customized changes to DNA. Because there are no additional sequences transferred, and alternations match what could happen naturally over time, the technology is considered less
"On Disinformation" Critical Conversations in the Post-Truth Era- Dr. Lee McIntyre
Information has been weaponized, and the ability to create false information to achieve an ideological goal has never been more easy. Political polarization, science denial, and a shining, effective conduit of dissemination (the internet) a
Therapeutics Controlling Protein Turnover - Dr. Juliet Williams
While DNA captures most of the fanfare, proteins are the catalytic and structural superstars of the cell. However, they can also become problematic. Cells have intricate mechanisms to remove damaged or mis-expressed proteins that could be d
Biohacking, DIY Biotech- Opportunities and Ethics with David Ishee
Recombinant DNA technologies once confined to the laboratory are now available to just about anyone. Is this a good thing or an extreme risk? David Ishee is self-described biohacker, dog breeder and mad scientist, and merges these passions
Rapid Detection of Dangerous Pathogens - Dr. Brad Perkins
We're surrounded by microbes, many that are the basis of disease. Others have evolved resistance to our best antibiotics. Others may be weaponized for bioterrorism. Because microbial threats can evolve rapidly and grow quickly, early detect
