
The Dr. Gabrielle Lyon Show· Staffel 1· Folge 234
The Testosterone Myth Women Have Been Lied To About │ Dr. Susan Hardwick-Smith
Dienstag, 8. September 2026 · 1 h 22
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Shownotes
You have probably been told that testosterone is a male hormone. Women produce more of it than estrogen, and for many of us it is the first hormone to go, sometimes reading zero five years before menopause while periods are still regular. Dr. Susan Hardwick-Smith and I get into what that costs you in muscle and bone, why there are thirty-one approved testosterone products for men and none for women, and what the number on your own lab report is measuring.
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Timestamps:
- Introduction: testosterone in women
- Eighteen years in OB-GYN and the practice she left
- Thirty years in medicine, zero training on testosterone
- 31 FDA-approved products for men, zero for women
- Why women produce more testosterone than estrogen
- What the ovaries stop making at menopause
- Testosterone reading zero five years early
- Low testosterone symptoms in women
- Intrinsa, the 2004 patch the FDA turned down
- Off-label prescribing and what FDA approval means
- Cognition, breast cancer, muscle and bone
- Osteoarthritis and the anti-inflammatory theory
- Dosing fears: hair loss, acne, voice changes
- Why gels are dosed ten times higher
- The 2019 international consensus
- Dividing a 50 mg tube by ten
- The Baylor study: pellet versus gel at six weeks
- Safety data from fifty years of transgender care
- Eight years of high dosing and what it cost
- Lab reference ranges versus optimal ranges
- ELISA versus LC-MS, and what the study found
- Why free testosterone is calculated, not measured
- Tachyphylaxis and chasing the number
- Pellets, BioTE and where the reputation came from
- Delivery methods, cypionate and enanthate
- Whether anything raises testosterone naturally
- DHEA at 100 mg and what it moved
- Drugs that lower testosterone in women
- Closing thoughts on dosing and access
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