Why Your Skin Isn’t Healing: The Gut, Hormone & Inflammation Connection

Early in my career, I noticed that patients’ skin often improved as we addressed their nutrition and gut health. That changed how I approached skin concerns and taught me to look beneath the surface for contributing factors.

Today, I’m joined by triple board-certified dermatologist Dr. Mamina Turegano, co-author of The Holistic Psoriasis Management and Nutrition Guide (amazon.com/dp/0778807304) and an advocate for Timeline’s approach to skin health. Together, we explore what your skin can reveal about your overall health and how that understanding can help you make more informed choices about caring for it.

You’ll learn:

• How damaged mitochondria contribute to skin aging, and how urolithin A may support healthier skin through mitochondrial renewal

• How your gut health, hormones, and insulin resistance may be contributing to recurring acne and other skin concerns

• How menopause changes your skin, and what to consider if it becomes drier, thinner, or less resilient

• How strength training may benefit your skin alongside your muscles

• Which skincare basics to prioritize before investing in newer treatments and supplements

Like most people, I care about how my skin looks, but I also want to understand what helps it stay healthy and resilient. That’s how I approach aging more broadly: learning what my body needs and making those choices part of everyday life.

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View Show Notes From This Episode (drhyman.com/blogs/content/podcast-ep1184)

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This episode is brought to you by Timeline, Sunlighten, Perfect Amino, Seed, BIOptimizers, and Pique.

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0:00 Strength training, skin thickness, and Sponsor: Timeline

1:46 Sunlighten infrared sauna, SIGNAL awards, and integrative dermatology from the inside out

5:53 Transition from conventional to holistic dermatology

9:29 Beyond the skin: diet, sleep, stress, hormones, and environment

10:14 Gut health, insulin resistance, and chronic skin disease drivers

12:23 Testing for SIBO, H. pylori, hormones, and gluten sensitivity

14:23 Sugar, dairy, environmental toxins, stress, caffeine, and inflammation as acne triggers

18:54 Functional treatment case: acne and psoriasis improvement

20:24 Comprehensive psoriasis workup and hidden drivers

22:16 Challenges in nutrition and lifestyle research; clinical observation

23:08 Healthy skin diet: Mediterranean eating, protein, fats, fiber, polyphenols, and processed foods

24:26 Elimination diets and foundational nutrients for skin health

27:50 The impact of hormones on skin health and aging

31:57 Functional medicine case studies: psoriasis, arthritis, and gut-focused treatment

36:25 Skin aging: effects of nutrition, lifestyle, hormones, and topical care

39:52 Alcohol, oxidative stress, and collagen breakdown in aging

41:00 Collagen supplements and UV radiation impact on skin

46:00 Supporting skin mitochondria: mitophagy, sleep, stress, exercise, and supplements

49:52 Urolithin A, polyphenols, carotenoids, and Sponsor: Timeline, Biooptimizers, Peak

54:52 Reversing skin aging and the role of strength training

57:42 Sun protection strategies for skin longevity

59:11 Melanoma risk, sun exposure patterns, and vitamin D

1:00:26 Major drivers of skin aging: sun, smoking, sugar, sleep, stress, exercise, pollution

1:02:26 Retinoids, vitamin C, and advanced therapies for skin repair

1:08:45 Dr. Mamina’s skincare routine and ingredient safety

1:14:55 Chemical vs. mineral sunscreens and rapid-fire takeaways

1:17:28 Where to find Dr. Mamina and learn about DermClick

1:18:15 Dr. Hyman’s new book, health lessons, and daily self-care

1:19:43 Supporting the show, following Dr. Hyman, and podcast disclaimer

1:20:21 Finding practitioners, Ultra Wellness Center, and closing thanks