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A weekly Python podcast hosted by Christopher Bailey with interviews, coding tips, and conversation with guests from the Python community.
The show covers a wide range of topics including Python programming best practices, career tips, and related software development topics. Join us every Friday morning to hear what's new in the world of Python programming and become a more effective Pythonista.
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Demystifying Python Memory Management & Choosing a Project Layout
<p>How does Python manage memory behind the scenes? What are the common ways to lay out a Python project? Christopher Trudeau is back on the show this week with another batch of PyCoder’s Weekly articles and projects.</p> <p>Christopher sha
The Future of Python Security: Trends, Challenges, and Solutions
<p>How is the Python ecosystem adapting to the modern landscape of software security and supply chain defense? This week on the show, we sit down with Seth Larson, the Python Software Foundation’s Security Developer in Residence.</p> <p>Set
Python Pitfalls: Common Mistakes and How to Avoid Them
<p>What are common mistakes that Python beginners make, and how do you avoid them? Christopher Trudeau is back on the show this week with another batch of PyCoder’s Weekly articles and projects.</p> <p>We dig into an article about common pi
Codemoo: Demonstrating How Coding Agents Work
<p>How do you assemble the core pieces of a coding agent? How are developers defining projects through conversation and introspection? This week on the show, Geir Arne Hjelle returns to talk about his recent project to demonstrate how codin
Python 3.15: Exploring the New Features
<p>Python 3.15 is (almost*) here! Christopher Trudeau and Bartosz Zaczyński return to discuss the new version. Bartosz coordinated the series of preview articles with members of the Real Python team and wrote the showcase tutorial, “Python
Navigating AI in Open Source: Insights From Wagtail
<p>How should you manage AI contributions to an open-source project? How do you measure the impact of using AI tools for development, and what generative features do end users want from a content management system? This week on the show, we
Django Developers Survey Results & Reproducible Python Builds
<p>What are the latest trends uncovered in the 2026 Django Developers Survey? How are Django users employing LLMs in their development process? Christopher Trudeau is back on the show this week with another batch of PyCoder’s Weekly article
Performance Engineering: Profiling and Making Apps Fast by Default
<p>How do you plan for the performance of your Python applications? What does a performance budget entail, and where should you spend your resources? This week on the show, we speak with Den Odell about his new book “Fast by Default: Practi
Exploring Complex Systems & Maintainable Data Science Pipelines
<p>What are the key characteristics of complex systems, and what are practical patterns for tackling complex coding problems? Christopher Trudeau is back on the show this week with another batch of PyCoder’s Weekly articles and projects.</p
Navigating Silent Failures in AI: Strategies for Effective Oversight
<p>Why do AI systems silently fail? How can you set up a system that produces results while also reviewing and validating the work? This week on the show, Calvin Hendryx-Parker returns to discuss his recent talk “Orchestrate Agentic AI: Con
Improving NumPy Performance on Free-Threaded Python
<p>What bottlenecks were preventing NumPy from scaling on free-threaded Python? Christopher Trudeau is back on the show this week with another batch of PyCoder’s Weekly articles and projects.</p> <p>Christopher shares a recent article on th
Programmatically Developing LLM Prompts With DSPy
<p>How can you move from manually writing prompts for an LLM application toward defining them programmatically? This week on the show, Brett Kennedy returns to discuss his new book “Building LLM Applications with DSPy.”</p> <p>With large la
Should You Understand Your Entire Python Codebase?
<p>Should you understand the entirety of your codebase? How familiar are you with Python’s built-in functions? Christopher Trudeau is back on the show this week with another batch of PyCoder’s Weekly articles and projects.</p> <p>We discuss
Configuring a Versatile LLM Harness & Scraping the Web With Scrapy
<p>Which is more important, the model or the “harness” around an LLM? What are ways to assemble an efficient agentic developer workflow? This week on the show, Ayan Pahwa joins us to discuss harnessing, web scraping, and self-hosting Python
Free-Threaded Python's History & uv in Production
<p>How many attempts have been made to remove Python’s Global Interpreter Lock (GIL)? How do they compare to the current approach? Christopher Trudeau is back on the show this week with another batch of PyCoder’s Weekly articles and project
Constructing and Judging Modern Agentic Workflows
<p>How can you improve your LLM agent systems through specification enrichment? What are the advantages of having an LLM act as a judge within an agent system? This week on the show, Senior IEEE Member and Quality Engineer Suneet Malhotra j
Running Python Locally in a Sandbox
<p>How do you avoid the risk of running a Python application locally that could be malicious, break your code, or leak private data? How can you create a sandboxed local environment using WASM and MicroPython? Christopher Trudeau is back on
Maintaining Your Python Developer Instincts While Using LLM Tools
<p>Do you feel like your Python skills are atrophying after using LLM coding tools? How do you add the right kind of friction into your coding routine to keep your developer instincts sharp? Christopher Trudeau is back on the show this week
EuroPython 2026: Celebrating 25 Years
<p>What’s happening at EuroPython 2026? The conference celebrates its 25th anniversary this year in Kraków, Poland. This week on the show, organizers Mia Bajić and Daria Linhart Grudzien join me to discuss this year’s conference.</p> <p>Mia
Reducing the Size of Python Docker Containers
<p>How can you easily reduce the size of a Python Docker container? What are the exceptions you should catch in your code? Christopher Trudeau is back on the show this week with another batch of PyCoder’s Weekly articles and projects.</p> <
Improving Python Through PEPs and Protocols
<p>Have you ever been confused by the naming of modules you’re importing from a package? Is there a standard way to organize and name your Python virtual environments? This week on the show, Brett Cannon returns to discuss the Python Enhanc
Managing Polars Schema Issues & Profiling GitHub Users
<p>How can you avoid schema problems in your Polars data pipeline when adding new columns? How can you quickly examine a GitHub user’s profile to decide how much to invest in their contributions? Christopher Trudeau is back on the show this
Agentic Architecture: Why Files Aren't Always Enough
<p>What are the limitations of using a file-based agent workflow? Why do massive context windows tend to collapse? This week on the show, Mikiko Bazeley from MongoDB joins us to discuss agentic architecture and context engineering.</p> <p>M
Declarative Charts in Python & Discerning Iterators vs Iterables
<p>What if you could build charts in Python by describing what your data means, instead of scripting every visual detail? Christopher Trudeau is back on the show this week with another batch of PyCoder’s Weekly articles and projects.</p> <p
Agentic Data Science Pair Programming With marimo pair
<p>How do you add agent skills to your data science workflow? How can a coding agent assist with data wrangling and research? This week on the show, Trevor Manz from marimo joins us to discuss marimo pair.</p> <p>Trevor is a founding engine
Becoming a Better Python Developer Through Learning Rust
<p>How can learning Rust help make you a better Python Developer? How do techniques required by a compiled language translate to improving your Python code? Christopher Trudeau is back on the show this week with another batch of PyCoder’s W
Reassessing the LLM Landscape & Summoning Ghosts
<p>What are the current techniques being employed to improve the performance of LLM-based systems? How is the industry shifting from post-training towards context engineering and multi-agent orchestration? This week on the show, Jodie Burch
Advice on Managing Projects & Making Python Classes Friendly
<p>What goes into managing a major project? What techniques can you employ for a project that’s in crisis? Christopher Trudeau is back on the show this week with another batch of PyCoder’s Weekly articles and projects.</p> <p>We discuss an
Limitations in Human and Automated Code Review
<p>With the mountains of Python code that it’s possible to generate now, how’s your code review going? What are the limitations of human review, and where does machine review excel? Christopher Trudeau is back on the show this week with ano
Automate Exploratory Data Analysis & Invent Python Comprehensions
<p>How do you quickly get an understanding of what’s inside a new set of data? How can you share an exploratory data analysis with your team? Christopher Trudeau is back on the show this week with another batch of PyCoder’s Weekly articles
