
This Is Your Brain On Drugs Psychiatry Podcast· Staffel 4· Folge 7
E101: Antipsychotics: D2 and 5HT2A Receptor Activity
Mittwoch, 28. Oktober 2026 · 1 h 00
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Shownotes
Today I will discuss how antipsychotics exert their positive effects on D2 and 5HT2A receptors. I will talk about intrinsic activity, partial agonism, pre-synaptic activity, antagonism, and the variety of effects the different antipsychotics exert on these receptors that changes how they work. This is a fundamental episode for understanding the differences and the mechanism of action of the antipsychotics so don't miss it!