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Ep 186 Hypothermia Part 1: How it hurts
For all our wondrous adaptations as a species - our big brains, our capacity for language, our opposable thumbs - we humans are not well-equipped to deal with the cold. Take us out of our insulated dwellings, take away our winter clothes, a
Special Episode: Lina Zeldovich & The Living Medicine
The development of antibiotics was one of the greatest turning points in the history of medicine. Bacterial infections that were once death sentences were cured within a matter of days after administration of these lifesaving compounds. But
Ep 185 The Great Smog of London: “Thick, drab, yellow, disgusting”
Some things just go together: peanut butter and jelly, bacon and eggs, milk and cereal, London and smog. Or at least, that’s the way things used to be until the Great Smog of 1952. (Don’t worry, the first three pairings are safe). If you’ve
Ep 184 The Gallbladder: Humor us
For most of us, there probably hasn’t been a good reason for you to think about your gallbladder. Ever. Much of the time, it sits there, silently storing, concentrating, and, when needed, churning out bile every day. But occasionally, this
Special Episode: Carl Zimmer & Airborne
In the first years of the COVID pandemic, a debate raged: was the virus transmitted via respiratory droplets, or was it airborne? For some, this distinction seemed overly technical, pedantic even. But for others, it represented decades of d
Ep 183 SSRIs Part 2: Action
Last week, we took you on a journey of discovery and innovation, and this week we’re gonna tell you how the heck it all works. That means a deep dive into the nitty gritty of SSRIs, from what serotonin does (A LOT, as it turns out), to why
Ep 182 SSRIs Part 1: Origin
Since first hitting the shelves nearly 40 years ago, SSRIs have become one of the most commonly prescribed classes of antidepressants around the world, as well as one of the most discussed and misunderstood. This and next week, we tell the
Special Episode: Wendy Chin-Tanner & King of the Armadillos
We’ve got a very special episode of the TPWKY book club this week! We’re featuring our very first fiction book: King of the Armadillos (https://bookshop.org/a/3175/9781250843029) by Wendy Chin-Tanner (https://wendychintanner.com/). This nov
Ep 181 PCOS: Beyond the cysts
What’s in a name? What can you really tell from a label like “polycystic ovarian syndrome”? And how much of that is more misconception than truth? The answer, as it turns out, is the former. In this episode, we delve into the world of PCOS,
Ep 180 Food Dyes: It’s all marketing
This episode, we aren’t asking you to taste the rainbow, but we are scrutinizing the artificial dyes that give it its color. When you’re munching on brightly colored candies or dipping a french fry in purple ketchup, what exactly is it you’
Special Episode: Professor Steven Mithen & The Language Puzzle
From the earliest grunts and gestures to the complex sentences we use today to convey a multitude of concepts, language has evolved to become one of humanity’s most powerful tools. It allows us to connect, create, conspire, control, console
Ep 179 Fluoride 2: Fighting tooth and nail
In last week’s episode, we traced the history of fluoridation (and the anti-fluoridation movement) to its roots in the early 20th century, but we left you wondering whether there’s anything to back up the health claims that anti-fluoridatio
Ep 178 Fluoride 1: The real tooth fairy
Is it just us, or does it seem like every other week there’s a new headline about some state or town banning water fluoridation? As it turns out, this has been going on for decades, basically since fluoride was first introduced. Why are som
Special Episode: Dr. Wendy Kline & Exposed
For many of us, pelvic exams are a routine part of our healthcare. Of course, that doesn’t mean we don’t await them with some dread or anxiety; naturally, these exams evoke a wide range of emotions. But they are a cornerstone in gynecologic
Ep 177 Toxic Shock Syndrome: A shock to the system
If you’ve ever read the little instructions pamphlet included in a box of tampons, you probably came across a paragraph calling attention to a condition called toxic shock syndrome (TSS). It describes the association between TSS and tampon
Ep 176 Strychnine: The WD-40 of Victorian Medicine
This week, we’re coming at you with a classic TPWKY episode on one of the most notorious poisons out there: strychnine. Although strychnine might not flash across too many headlines these days, it was once imported by the ton in certain reg
Special Episode: Dr. Adam Ratner & Booster Shots
For the past few months, measles has been in regular rotation in the news cycle here in the US, with outbreaks occurring across the country in regions with low vaccine uptake. These outbreaks represent a worrying trend in the rejection of s
Ep 175 What’s the deal with raw milk: Part 2
Last week, we started this two-parter with a big picture view of pasteurization and the raw milk movement. In this episode, we address the alleged health claims made by proponents of raw milk and dive into the very real risks carried by its
Ep 174 What’s the deal with raw milk: Part 1
Seriously, what’s the deal? Lately, it seems like raw milk has started to pop up more and more frequently in our feeds, with influencers touting the alleged health benefits of raw milk over pasteurized milk. In this and next week’s episode,
Special Episode: John Green & Everything Is Tuberculosis
Tuberculosis, or consumption as it was once known, might conjure up images of huge sanitoriums or writers and artists from the late 1800s (Moulin Rouge, anyone?). But this deadly disease is far from an illness of the past. In many parts of
Ep 173 Childhood Vaccine Schedule 2: Who’s making the call?
After last week’s episode, we all know about each of the diseases that we’re protected against thanks to our childhood vaccine schedule here in the US. And after this week’s episode, we’ll understand more about the schedule itself - why it
Ep 172 Childhood Vaccine Schedule 1: Let’s give it a shot
We’re already back with our first episode of season 8! This week and next, we’re exploring childhood vaccine schedules - what diseases they protect us from, how the schedule is arranged, and who decides on the vaccines to include and the ti
Ep 171 Pregnancy: Act 4
Content Warning: This episode includes mentions of miscarriage, pregnancy loss, pregnancy complications, traumatic birth experiences, and other potentially disturbing topics related to childbirth, pregnancy, and the postpartum period. We cl
Ep 170 Pregnancy: Act 3
Content Warning: This episode includes mentions of miscarriage, pregnancy loss, pregnancy complications, traumatic birth experiences, and other potentially disturbing topics related to childbirth, pregnancy, and the postpartum period. In Ac
Ep 169 Pregnancy: Act 2
Content Warning: This episode includes mentions of miscarriage, pregnancy loss, pregnancy complications, traumatic birth experiences, and other potentially disturbing topics related to childbirth, pregnancy, and the postpartum period. The s
Ep 168 Pregnancy: Act 1
Content Warning: This episode includes mentions of miscarriage, pregnancy loss, pregnancy complications, traumatic birth experiences, and other potentially disturbing topics related to childbirth, pregnancy, and the postpartum period. With
Special Episode: Rachel Gross & Vagina Obscura
For much of history, female reproductive anatomy has been studied only in the context of or in comparison to male reproductive anatomy. This shows in clinical trial design, in healthcare disparities, in the research questions we ask (or fai
Ep 167 Viagra/Sildenafil: Raising the bar
Has a name brand prescription medication ever shot to notoriety as quickly as Viagra did? Within a few months of its arrival on the market, it seems like everyone knew about the little blue pill, whether through commercials featuring celebr
Ep 166 Amanita poisoning: Death Cap-tivating
In forests, in lawns, in city parks across the world lurks a small, pale, unassuming mushroom whose inconspicuous appearance belies its deadly nature. For within this mushroom dwelsl one of the deadliest poisons known to humans: amatoxin. I
Ep 165 Fish Tongue Parasite: Parasite Appreciation Hour
Okay everyone, think about your tongue. Maybe move it around a bit, check in with it, consider what it means to you. Now imagine that your tongue suddenly shriveled up and fell off and that in its place is a tongue-sized isopod aka rollie p
