This Week in Startups

Why Your Company Should Own Its AI Model | E2278

Dienstag, 21. April 2026 · 1 h 17

MP3

Shownotes

This Week In Startups is made possible by:
Quo - quo.com/TWiST Vanta -
vanta.com/twist
Pilot - pilot.com/twist Plaud -
Plaud.ai/twist

Today's show:

*Eragon CEO Josh Sirota believes that you should "own your intelligence." He demos a live enterprise AI operating system connecting email, Slack, calendar, and financial data into a single agentic layer that's pre-trained to understand any business inside and out.

PLUS we've got IONA Drones founder Etienne Louvet, a first look at Moonshot's Kimi K2.6, and a brand new Off Duty with JCal and Lon.

FULL SHOW NOTES ON NOTION: thisweekinstartups-docket.notion.site/TWiST-22…

Guests :
Eragon: eragon.ai
Josh Sirota on X: x.com/joshua_sirota
IONA: ionadrones.com
Etienne Louvet on X: x.com/etienneldva
Relevant Links
Eragon Seed Round coverage: techcrunch.com/2026/03/18/this-startup-wants-t…
Neurometric: neurometric.ai
Ollama model: ollama.com
Orange Slice: orangeslice.ai
Corgi Insurance: corgi.insure
Slash Financial: slash.com
The Syndicate: thesyndicate.com
FAA Part 108 Explained: pilotinstitute.com/part-108-explained
Zipline: zipline.com
Google Wing: wing.com
Joby Aviation: jobyaviation.com
Enterprise Ireland: enterprise-ireland.com
Éire Composites: eirecomposites.com
Kimi K2.6 blog post: kimi.com/blog/kimi-k2-6
Kimi K2 series on GitHub: github.com/moonshotai/Kimi-K2
NVIDIA GB300 NVL72 work station: nvidia.com/en-us/data-center/gb300-nvl72

Timestamps:
Josh from Eragon AI joins the show
Plaud: If your work depends on conversations — interviews, meetings, calls — you need a Plaud NotePin. You can check it out at Plaud.ai/twist and use code TWIST for 10% off!
Why founders should own and control their data sets
What is a "company world model?"
Quo (formerly OpenPhone) - Quo gives you a clean, modern way to handle every customer call, text, and thread all in one place. Try it free at quo.com/TWiST
Eragon demo
Giving agents their own bank accounts
Inside Eragon's first partnerships
Vanta - Get $1000 off your SOC 2 at vanta.com/twist
How does Eragon make money?
Pilot - Visit pilot.com/twist and get $1,200 off your first year.
Etienne Louvet of Iona Drones joins the show
What is FAA's Part 108?
How innovation in drones impacts the aviation industry
Working with Enterprise Ireland
Jason attended the Breakthrough Awards
Doug Liman's AI-powered "Bitcoin" movie
"Love Story" on FX and "Dust Bunny" on HBO Max
Jason's love of tinned fish
Subscribe to the TWiST500 newsletter: ticker.thisweekinstartups.com
Check out the TWIST500: twist500.com
Subscribe to This Week in Startups on Apple: rb.gy/v19fcp
Follow Lon:
X: x.com/lons
Follow Alex:
X: x.com/alex
LinkedIn: ⁠linkedin.com/in/alexwilhelm (linkedin.com/in/alexwilhelm)
Follow Jason:
X: twitter.com/Jason
LinkedIn: linkedin.com/in/jasoncalacanis

Check out all our partner offers: partners.launch.co
Great TWIST interviews: Will Guidara, (youtu.be/pvJa2pzuXWQ) Eoghan McCabe (youtu.be/9dHN4YFkgv4), Steve Huffman (podcasts.apple.com/us/podcast/reddit-ceo-steve…), Brian Chesky (podcasts.apple.com/ca/podcast/airbnb-ceo-brian…), Bob Moesta, (youtu.be/y2UMzSqX94Q) Aaron Levie (podcasts.apple.com/ca/podcast/box-ceo-aaron-le…), Sophia Amoruso (podcasts.apple.com/ca/podcast/sophia-amoruso-o…), Reid Hoffman (podcasts.apple.com/ca/podcast/reid-hoffman-on-…), Frank Slootman (podcasts.apple.com/ca/podcast/snowflake-ceo-fr…), Billy McFarland (podcasts.apple.com/ca/podcast/billy-mcfarland-…)
Check out Jason's suite of newsletters: substack.com/@calacanis
Follow TWiST:
Twitter: twitter.com/TWiStartups
YouTube: youtube.com/thisweekin
Instagram: instagram.com/thisweekinstartups
TikTok: tiktok.com/@thisweekinstartups
Substack: twistartups.substack.com

0:00 / 0:00