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This Week in Startups

von Jason Calacanis

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  1. Bittensor's (alleged) $10M rug pull (feat. Mark Jeffrey) | E2275

    This Week In Startups is made possible by: Sentry - https://sentry.io/twist Deel - https://deel.com/twist Netsuite - https://netsuite.com/twist Plaud - https://Plaud.ai/twist (http://plaud.ai/twist) Today's show: *TAO just had its worst wee

  2. Bittensor Drama! TAO down 15%! | E2274

    This Week In Startups is made possible by: Pilot - https://pilot.com/TWIST (http://pilot.com/twist) Squarespace -https://squarespace.com/TWIST (https://squarespace.com/twist) Northwest Registered Agent - http://northwestregisteredagent.com/

  3. Anthropic's Mythos is a cyber-weapon, so you can't have it | E2273

    Anthropic just built a model so dangerous, they're not even going to release it (for now). On TWiST, Jason, Alex, and Neurometric CEO Rob May discuss whether or not this is just another frontier model or a potential weapon of mass internet

  4. 3 AI Agents That Actually Replaced Human Jobs | E2272

    Anthropic just pulled the plug on Claude subscriptions for OpenClaw and every third party agentic tool. So Jason and Lon welcome back three of our top TWiST OpenClaw experts to break down what it means, how much it's going to cost now, and

  5. AI Rebuilt Every YC W26 Startup. Should Founders Be Scared? | E2271

    This Week In Startups is made possible by: Deel - deel.com/twist Grasshopper Bank - grasshopper.bank/twist Render - render.com/twist Plaud - Plaud.ai/twist An AI "holding company" rebuilt dozens of YC Winter '26 startups in one weekend. Now

  6. How 3 CEOs Use AI to Run $10B in Companies | This Week in AI

    This Week in AI, JCal sits down with three CEOs building the infrastructure, intelligence, and interfaces for the next era of AI: Jeremy Fraenkel (CEO, Fundamental), Victor Riparbelli (CEO, Synthesia), and Nick Harris (CEO, Lightmatter). We

  7. Venture Roundtable: SpaceX IPO, AI's PR Crisis, and the Defense Tech Bubble | E2270

    This Week In Startups is made possible by: PaperOS - https://PaperOS.com/twist (http://paperos.com/twist) Northwest Registered Agent- http://northwestregisteredagent.com/twist Every.io (http://every.io) - https://Every.io (http://every.io/)

  8. The 5-Step Framework for AI Agents That Improve While You Sleep | E2269

    This Week In Startups is made possible by: Quo - https://http://quo.com/TWiST LinkedIn Jobs - https://LinkedIn.com/twist (http://linkedin.com/HiringProOffer) Iru - https://http://iru.com/twist Plaud - https://Plaud.ai/twist (http://plaud.ai

  9. The $60 billion resource hiding in space, and the start trying to mine it (feat. Matt Gialich, Astroforge) | E2268

    This Week In Startups is made possible by: Wispr Flow - https://https://wisprflow.ai/twist Circle - http://circle.so/twist Deel - http://circle.so/twisthttp://deel.com/twist Today's show: AstroForge is building low-cost, replicable spacecra

  10. This Bittensor Subnet Could Cut Drug Discovery Costs in HALF | E2267

    This Week In Startups is made possible by: Luma AI - http://lumalabs.ai/twist Every.io (http://every.io) - https://http://every.io/ Lemon.io (http://lemon.io) - https://lemon.io/twisthttps://Lemon.io/twist (http://lemon.io/twist)Plaud - htt

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