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Greetings, Earthlings: Philip Johnston of Starcloud on Data Centers in Space
Philip Johnston, founder and CEO of Starcloud, explains why space will become the primary location for AI compute infrastructure within the next decade. After witnessing SpaceX's massive manufacturing scale at Starbase, Philip realized that
Physics Gets a Vote: Nominal Cofounders on Hardware Development in an AI World
Nominal’s cofounders (Cameron McCord, Jason Hoch and Bryce Strauss) realized that the new age of reindustrialization requires a new approach to hardware engineering and testing that’s closer to how software is developed. They founded Nomina
Building the GitHub for RL Environments: Prime Intellect's Will Brown & Johannes Hagemann
Will Brown and Johannes Hagemann of Prime Intellect discuss the shift from static prompting to "environment-based" AI development, and their Environments Hub, a platform designed to democratize frontier-level training. The conversation high
What’s the Future of Vertical SaaS in an AGI World? Jamie Cuffe, CEO of Pace
Jamie Cuffe is solving one of AI's hardest problems: getting conservative, regulated industries to trust autonomous agents with mission-critical work. At Pace, he's building AI that replaces traditional BPOs in insurance, handling everythin
Making the Case for the Terminal as AI's Workbench: Warp’s Zach Lloyd
Zach Lloyd built Warp to modernize the terminal for professional developers, but the rise of coding agents transformed his company's trajectory. He discusses the convergence of IDEs and terminals into new workbenches built for prompting and
Context Engineering Our Way to Long-Horizon Agents: LangChain’s Harrison Chase
Harrison Chase, cofounder of LangChain and pioneer of AI agent frameworks, discusses the emergence of long-horizon agents that can work autonomously for extended periods. Harrison breaks down the evolution from early scaffolding approaches
How Ricursive Intelligence’s Founders are Using AI to Shape The Future of Chip Design
Anna Goldie and Azalia Mirhoseini created AlphaChip at Google, using AI to design four generations of TPUs and reducing chip floor planning from months to hours. They explain how chip design has become the critical bottleneck for AI progres
Training General Robots for Any Task: Physical Intelligence’s Karol Hausman and Tobi Springenberg
Physical Intelligence’s Karol Hausman and Tobi Springenberg believe that robotics has been held back not by hardware limitations, but by an intelligence bottleneck that foundation models can solve. Their end-to-end learning approach combine
Why the Next AI Revolution Will Happen Off-Screen: Samsara CEO Sanjit Biswas
Sanjit Biswas is one of the rare founders who has scaled AI in the physical world – first with Meraki, and now with Samsara, a $20B+ public company with sensors deployed across millions of vehicles and job sites. Capturing 90 billion miles
The Rise of Generative Media: fal's Bet on Video, Infrastructure, and Speed
fal is building the infrastructure layer for the generative media boom. In this episode, founders Gorkem Yurtseven, Burkay Gur, and Head of Engineering Batuhan Taskaya explain why video models present a completely different optimization pro
Why IDEs Won't Die in the Age of AI Coding: Zed Founder Nathan Sobo
Nathan Sobo has spent nearly two decades pursuing one goal: building an IDE that combines the power of full-featured tools like JetBrains with the responsiveness of lightweight editors like Vim. After hitting the performance ceiling with we
How End-to-End Learning Created Autonomous Driving 2.0: Wayve CEO Alex Kendall
Alex Kendall founded Wayve in 2017 with a contrarian vision: replace the hand-engineered autonomous vehicle stack with end-to-end deep learning. While AV 1.0 companies relied on HD maps, LiDAR retrofits, and city-by-city deployments, Wayve
How Google’s Nano Banana Achieved Breakthrough Character Consistency
When Google launched Nano Banana, it instantly became a global phenomenon, introducing an image model that finally made it possible for people to see themselves in AI-generated worlds. In this episode, Nicole Brichtova and Hansa Srinivasan,
OpenAI Sora 2 Team: How Generative Video Will Unlock Creativity and World Models
The OpenAI Sora 2 team (Bill Peebles, Thomas Dimson, Rohan Sahai) discuss how they compressed filmmaking from months to days, enabling anyone to create compelling video. Bill, who invented the diffusion transformer that powers Sora and most
Nvidia CTO Michael Kagan: Scaling Beyond Moore's Law to Million-GPU Clusters
Recorded live at Sequoia’s Europe100 event: Michael Kagan, co-founder of Mellanox and CTO of Nvidia, explains how the $7 billion Mellanox acquisition helped transform Nvidia from a chip company into the architect of AI infrastructure. Kagan
Securing the AI Frontier: Irregular Co-founder Dan Lahav
Irregular co-founder Dan Lahav is redefining what cybersecurity means in the age of autonomous AI. Working closely with OpenAI, Anthropic, and Google DeepMind, Dan, co-founder Omer Nevo and team are pioneering “frontier AI security”—a proac
Why AI Will Transform Customer Experience: Cresta CEO Ping Wu and Sequoia’s Doug Leone
Ping Wu built Google's contact center business before becoming CEO of Cresta, where he's pioneering a unique approach to contact center transformation. Rather than full automation Ping advocates a dual approach, automating what's ready whil
Block CTO Dhanji Prasanna: Building the AI-First Enterprise with Goose, their Open Source Agent
As CTO of Block, Dhanji Prasanna has overseen a dramatic enterprise AI transformation, with engineers saving 8-10 hours a week through AI automation. Block’s open-source agent goose connects to existing enterprise tools through MCP, enablin
Why Businesses Are Rejecting the AI They’ve Asked For: Agency CEO Elias Torres
Elias Torres has been building AI systems since 1999, from chatbots at IBM to co-founding Drift and now Agency. He believes businesses are caught in an expectation mismatch—demanding AI while rejecting it due to imperfection anxiety. Drawin
Building the "App Store" for Robots: Hugging Face's Thomas Wolf on Physical AI
Thomas Wolf, co-founder and Chief Science Officer of Hugging Face, explains how his company is applying the same community-driven approach that made transformers accessible to everyone to the emerging field of robotics. Thomas discusses LeR
Deal Velocity, Not Billable Hours: How Crosby Uses AI to Redefine Legal Contracting
Ryan Daniels and John Sarihan are reimagining legal services by building Crosby, an AI-powered law firm that focuses on contract negotiations to start. Rather than building legal software, they've structured their company as an actual law f
n8n CEO Jan Oberhauser on Building the Universal AI Automation Layer
When the AI wave hit, n8n founder Jan Oberhauser faced a critical choice: become irrelevant or become indispensable. He chose the latter, transforming n8n from a simple workflow tool into a comprehensive AI automation platform that lets use
Scaling the ‘Cursor for Slides’ to $50M ARR: Gamma founder Jon Noronha
Before ChatGPT made AI mainstream, John Noronha was building Gamma with a simple insight: everyone hates making slides but needs visual communication for high-stakes ideas. His background at Optimizely proved crucial as Gamma became a testi
Delphi’s Dara Ladjevardian: How AI Digital Minds Can Scale Human Connection
Dara Ladjevardian, founder and CEO of Delphi, is creating digital minds that allow people to scale their thoughts and availability without replacing human connection. Inspired by Ray Kurzweil’s theory of mind as a hierarchy of pattern recog
Vercel CEO Guillermo Rauch: Building the Generative Web with AI
Vercel CEO Guillermo Rauch has spent years obsessing over reducing the friction between having an idea and getting it online. Now with AI, he's achieving something even more ambitious: making software creation accessible to anyone with a ke
OpenAI’s IMO Team on Why Models Are Finally Solving Elite-Level Math
In just two months, a scrappy three-person team at OpenAI sprinted to fulfill what the entire AI field has been chasing for years—gold-level performance on the International Mathematical Olympiad problems. Alex Wei, Sheryl Hsu and Noam Brow
OpenAI Just Released ChatGPT Agent, Its Most Powerful Agent Yet
Isa Fulford, Casey Chu, and Edward Sun from OpenAI's ChatGPT agent team reveal how they combined Deep Research and Operator into a single, powerful AI agent that can perform complex, multi-step tasks lasting up to an hour. By giving the mod
DeepMind's Pushmeet Kohli on AI's Scientific Revolution
Pushmeet Kohli leads AI for Science at DeepMind, where his team has created AlphaEvolve, an AI system that discovers entirely new algorithms and proves mathematical results that have eluded researchers for decades. From improving 50-year-ol
Mapping the Mind of a Neural Net: Goodfire’s Eric Ho on the Future of Interpretability
Eric Ho is building Goodfire to solve one of AI’s most critical challenges: understanding what’s actually happening inside neural networks. His team is developing techniques to understand, audit and edit neural networks at the feature level
ElevenLabs’ Mati Staniszewski: Why Voice Will Be the Fundamental Interface for Tech
Mati Staniszewski, co-founder and CEO of ElevenLabs, explains how staying laser-focused on audio innovation has allowed his company to thrive despite the push into multimodality from foundation models. From a high school friendship in Polan