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- 7. Aug.letzte Folge
Artificial intelligence is changing everything from art to enterprise IT, and a16z is watching all of it with a close eye. This podcast features discussions with leading AI engineers, founders, and experts, as well as our general partners, about where the technology and industry are heading.
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How AI Is Rewriting the Rules of Cybersecurity | Truffle Security & Socket
Joel De La Garza is joined by Dylan Ayrey, co-founder and CEO of Truffle Security, and Feross Aboukhadijeh, founder and CEO of Socket, to discuss one of the biggest shifts happening in cybersecurity: AI models are no longer just finding vul
Inside vLLM: The Engine Powering Open-Source AI
Elena Burger and Matt Bornstein are joined by Simon Mo, co-founder and CEO of Inferact, the open-source inference engine powering many of today's most advanced AI applications. Together, they explore how open-source AI evolved from a resear
Building Self-Accelerating AI with Mirendil
Matt Bornstein speaks with Mirendil cofounders Behnam Neyshabur and Harsh Mehta about their vision for building self-accelerating AI. After leading research efforts at Google and Anthropic, the founders started Mirendil around a simple ques
Ideogram’s Open-Weights Image Model and the Future of AI Design
Yoko Li and Justine Moore speak with Ideogram founder and CEO Mohammad Norouzi about image generation models, design workflows, and the evolving relationship between AI and creative work. The conversation covers Ideogram's decision to relea
Building Search for AI Agents with Exa CEO Will Bryk
Sarah Wang speaks with Exa cofounder and CEO Will Bryk about building search infrastructure for the AI era. The conversation covers Exa’s origins, why traditional search engines were not designed for AI agents, and how search changes when t
AI Agents and the Fight for Customer Data
Martin Casado speaks with George Fraser, cofounder and CEO of Fivetran, about the future of data infrastructure in the age of AI. The conversation covers Fivetran’s merger with dbt, the changing role of data platforms, and why Fraser believ
Ben Horowitz on AI Infrastructure, Economics and The New Laws of Software
Recorded live at the a16z Fintech Connect conference in Deer Valley, Alex Rampell speaks with Ben Horowitz, cofounder and general partner at a16z, about how AI has rewritten the fundamental rules of software competition, why crypto infrastr
AI Infrastructure, Distribution, and the Next Wave of Software
Sophie Buonassisi speaks with Jennifer Li, general partner at a16z, about why infrastructure is becoming one of the most important areas in AI. They discuss how the shift to AI-native systems is reshaping everything from storage and compute
From Vector Databases to Knowledge Engines: The Next Layer of AI
Peter Levine speaks with Ash Ashutosh, CEO of Pinecone, about the launch of Nexus and the shift from vector databases to knowledge engines. As agents become the primary users of software, they discuss why traditional retrieval systems break
Why We Need Continual Learning
Elena Burger speaks with Malika Aubakirova, partner on the AI infrastructure team at a16z, about why today’s AI systems struggle to learn over time. They discuss the limits of in-context learning, the case for continual learning, and how mo
The Agent Era: Building Software Beyond Chat with Box CEO Aaron Levie
Erik Torenberg, Steve Sinofsky, and Martin Casado speak to Aaron Levie, CEO at Box, about what happens to enterprise software when agents become the primary users. They discuss why coding agents succeed where other knowledge work agents str
Rethinking Git for the Age of Coding Agents with GitHub Cofounder Scott Chacon
Matt Bornstein speaks with Scott Chacon, cofounder of GitHub and CEO of GitButler, about why Git's user interface has barely changed since 2005, how GitButler is rethinking version control for both humans and AI agents, and what the "next G
How AI Is Reshaping IT Services from the Inside
Joe Schmidt speaks with Peter Doyle, CEO of Treeline, about why the $100B managed service provider market is a decade behind modern technology and how Treeline is building a new model that combines human technicians with AI and automation.
Patrick Collison on Stripe’s Early Choices, Smalltalk, and What Comes After Coding
Michael Truell, CEO of Cursor, sits down with Patrick Collison, CEO of Stripe and an investor in Anysphere, to talk about Collison's history with Smalltalk and Lisp, the MongoDB and Ruby decisions Stripe still lives with 15 years later, why
OpenClaw: Why the Internet Isn't Built for AI Agents
Yoko Li, Guido Appenzeller, and Joel de la Garza discuss OpenClaw, the open source personal AI assistant that's forcing a rethink of how identity, permissions, and security work on the internet. They cover why setting up Gmail integration t
What's Missing Between LLMs and AGI - Vishal Misra & Martin Casado
Vishal Misra returns to explain his latest research on how LLMs actually work under the hood. He walks through experiments showing that transformers update their predictions in a precise, mathematically predictable way as they process new i
Replit's CEO on Vibe Coding, Wealth Building, and What Most People Get Wrong About AI
Jack Neel speaks with Amjad Masad, CEO at Replit, about how AI is making it easier than ever to build and ship software without a technical background. They discuss Replit's rise from a browser-based coding tool to a platform generating $25
Jack Altman & Martin Casado on the Future of VC
Jack Altman sits down with Martin Casado, General Partner at a16z, to unpack the shifting dynamics of venture capital and why media matters more than ever. They cover a16z’s evolution from generalists to specialized platforms, the rise of A
AI’s Capital Flywheel: Models, Money, and the Future of Power
a16z's Martin Casado and Sarah Wang join Latent Space hosts Alessio Fanelli and Swyx to discuss what makes this AI investment cycle unlike anything in the history of venture capital. They cover why the lines between venture and growth, apps
Durable Execution and the Infrastructure Powering AI Agents
Raghu Raghuram, Managing Partner at a16z, and Sarah Wang, General Partner at a16z, speak with Samar Abbas, CEO of Temporal, about how durable execution became the infrastructure layer behind some of the world’s most widely used AI agents. T
Evals, Feedback Loops, and the Engineering That Makes AI Work
Martin Casado speaks with Ankur Goyal, founder and CEO of Braintrust, about where engineering actually matters in AI and where it doesn't. They cover the open source vs closed source model cycle, why Chinese models are gaining ground faster
Sam Altman on Sora, Energy, and Building an AI Empire
Sam Altman has led OpenAI from its founding as a research nonprofit in 2015 to becoming the most valuable startup in the world ten years later. In this episode, a16z Cofounder Ben Horowitz and General Partner Erik Torenberg sit down with Sa
Why This Isn't the Dot-Com Bubble | Martin Casado on WSJ's BOLD NAMES
Christopher Mims and Tim Higgins of the Wall Street Journal sit down with a16z General Partner Martin Casado on WSJ’s Bold Names to ask whether the AI spending boom is a bubble waiting to burst. Martin explains why the fundamentals differ d
Martin Casado on the Demand Forces Behind AI
In this feed drop from The Six Five Pod, a16z General Partner Martin Casado discusses how AI is changing infrastructure, software, and enterprise purchasing. He explains why current constraints are driven less by technical limits and more b
How Mintlify Is Rebuilding Documentation for Coding Agents
Mintlify is a documentation platform built by cofounders Han Wang and Hahnbee Lee to help teams create and maintain developer docs. In this episode, Andreessen Horowitz general partners Jennifer Li and Yoko Li speak with Han and Hahnbee abo
Inferact: Building the Infrastructure That Runs Modern AI
Inferact is a new AI infrastructure company founded by the creators and core maintainers of vLLM. Its mission is to build a universal, open-source inference layer that makes large AI models faster, cheaper, and more reliable to run across a
How Should AI Be Regulated? Use vs. Development
To Regulate AI Effectively, Focus on How It’s Used A conversation with Martin Casado on learning from past computing platform shifts, understanding marginal risk in AI, and why open source matters for US competitiveness. One of the core pil
Michael Truell: How Cursor Builds at the Speed of AI
When four MIT grads decided to build a code editor while everyone else was building AI agents, they created the fastest-growing developer tool ever built. Cursor CEO Michael Truell joins a16z’s Martin Casado to discuss the deliberate constr
Dylan Patel on the AI Chip Race - NVIDIA, Intel & the US Government
Nvidia’s $5 billion investment in Intel is one of the biggest surprises in semiconductors in years. Two longtime rivals are now teaming up, and the ripple effects could reshape AI, cloud, and the global chip race. To make sense of it all, E
Feed Drop from The Generalist: Why a16z's Martin Casado believes the AI boom still has years to run
This episode is a special replay from The Generalist Podcast, featuring a conversation with a16z General Partner Martin Casado. Martin has lived through multiple tech waves as a founder, researcher, and investor, and in this discussion he s
