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Fei-Fei Li: World Models and the Multiverse
What if the next leap in artificial intelligence isn’t about better language—but better understanding of space? In this episode, a16z General Partner Erik Torenberg moderates a conversation with Fei-Fei Li, cofounder and CEO of World Labs,
Building the “See Something, Say Something” AI for Every Camera
a16z's Martin Casado sits down with Shikhar Shrestha, CEO and cofounder of Ambient, the company bringing agentic AI to physical security. Shikhar shares how a traumatic armed robbery at age 12—and a security camera that no one was watching—
The AI That Found A Bug In The World’s Most Audited Code
Matt Knight spent five years as OpenAI’s CISO. Now he runs what colleagues call “the most interesting job at the company”: leading Aardvark, an AI agent that finds security vulnerabilities the way a human researcher would—by reading code, w
The Death of Data Gatekeeping: AI Makes Everyone An Analyst | Hex Cofounder
Most companies still rely on dashboards to understand their data, even though AI now offers new ways to ask questions and explore information. Barry McCardel, CEO of Hex and former engineer at Palantir, joins a16z General Partner Sarah Wang
Why Social Engineering Now Works on Machines
Ian Webster built PromptFoo after watching 200 million Discord users systematically dismantle his AI agent—now Fortune 10 companies pay him to break theirs before customers do. The "lethal trifecta" sounds academic until you realize it's al
“Anyone Can Code Now” - Netlify CEO Talks AI Agents
Netlify's CEO, Matt Biilmann, reveals a seismic shift nobody saw coming: 16,000 daily signups—five times last year's rate—and 96% aren't coming from AI coding tools. They're everyday people accidentally building React apps through ChatGPT,
From Code Search to AI Agents: Inside Sourcegraph's Transformation with CTO Beyang Liu
Sourcegraph's CTO just revealed why 90% of his code now comes from agents—and why the Chinese models powering America's AI future should terrify Washington. While Silicon Valley obsesses over AGI apocalypse scenarios, Beyang Liu's team disc
Ryo Lu (Cursor): AI Turns Designers to Developers
Ryo Lu spent years watching his designs die in meetings. Then he discovered the tool that lets designers ship code at the speed of thought: Cursor, the company where Ryo is now Head of Design. In this episode, we discuss why "taste" is the
How Foundation Models Evolved: A PhD Journey Through AI's Breakthrough Era
The Stanford PhD who built DSPy thought he was just creating better prompts—until he realized he'd accidentally invented a new paradigm that makes LLMs actually programmable. While everyone obsesses over whether LLMs will get us to AGI, Oma
TruffleHog Creator: You Can’t Have AI Agents Without Secrets
If you can’t robustly protect your secrets, you can’t have reliable AI agents. In this episode, Truffle Security cofounder and CEO Dylan Ayrey joins a16z partner Joel de la Garza to discuss the emergent security stack for AI agents, why lea
Tigris Data CEO on Building Your Own Datacenters
In this episode, a16z General Partner Martin Casado sits down with Ovais Tariq, Cofounder and CEO of Tigris Data, to discuss why independent storage is so hard, what operating your own datacenters is like, and what’s in store for the future
Pylon: Reimagining B2B Customer Support
Customer support platforms lacked adequate solutions for B2B companies - until Pylon entered the scene. We sat down with Pylon cofounders Marty Kausas, Advith Chelikani, and Robert Eng to discuss why they went into B2B, how they plan to bea
Keycard: 2026 is the Year of Agents
In 2025, we saw the first glimpses of true AI agents. In 2026, every company will be rushing to get them into production, and they’ll need companies like Keycard to manage fleets of agents. In this conversation, a16z Partner Joel de la Garz
The Trillion Dollar AI Software Development Stack
AI coding has emerged as a major market for AI: one that’s already rewriting how software gets built. a16z Infra Partners Yoko Li and Guido Appenzeller break down how “agents with environments” are changing the dev loop; why repos and PRs m
Material Security CEO: How To Find Your Ideal Customer
What if the hardest part of building a company isn’t the product, but knowing exactly who it’s for? In this episode, a16z General Partner Martin Casado sits down with Abhishek Agrawal, Cofounder and CEO of Material Security, to discuss how
When Deepfakes Steal $30M: The New Edge of Cybercrime
AI is transforming both sides of the cybersecurity cat-and-mouse game. Attackers are using LLMs to scale impersonation, phishing, and even deepfake fraud—while defenders are racing to automate detection and takedowns at the same speed. In t
How AI Will Change Photography Forever
What if you could retake your favorite memories years after they happened, fixing the lighting, catching the smile, or even opening your eyes? In this conversation, a16z General Partner Martin Casado and Partner Yoko Li sit down with scient
How OpenAI Built Its Coding Agent
OpenAI’s Codex has already shipped hundreds of thousands of pull requests in its first month. But what is it really, and how will coding agents change the future of software? In this episode, General Partner Anjney Midha goes behind the sce
Models, Modalities, and Memes: Creating Compelling AI Characters
Models, Modalities, and Memes: Creating Compelling AI Characters In this episode of AI + a16z, Hedra founder and CEO Michael Lingelbach joins a16z partners Justine Moore and Matt Bornstein to talk about building AI-native video — and why th
Performance and Passion: Fal's Approach to AI Inference
If you've been experimenting with image, video, and audio models, the chances are you've been both blown away by how good they're becoming, and also a little perturbed by how long they can take to generate. If you've been using a platform l
How to Vibe Code Securely
In this episode, a16z partner Joel de la Garza sits down with Socket (https://socket.dev/) founder and CEO Feross Aboukhadijeh to dive into the intersection of vibe coding and security. As one of the earliest security founders to fully embr
AI Is Upending SaaS Pricing
In this episode, a16z GP Martin Casado sits down with Metronome (https://metronome.com/) CEO Scott Woody to unpack how AI is fundamentally changing the value proposition of software—and why that shift demands a rethink of the traditional Sa
The AI Infrastructure Stack with Jennifer Li
In this episode, which originally aired on the Complex Systems Podcast (https://www.complexsystemspodcast.com/), a16z General Partner Jennifer Li discusses how AI is reshaping every layer of the software stack, creating demand for new types
AI's Unsung Hero: Data Labeling and Expert Evals
Labelbox (https://labelbox.com/) CEO Manu Sharma joins a16z Infra partner Matt Bornstein to explore the evolution of data labeling and evaluation in AI — from early supervised learning to today’s sophisticated reinforcement learning loops.
AI, Data Engineering, and the Modern Data Stack
In this episode of AI + a16z, dbt Labs (https://www.getdbt.com/) founder and CEO Tristan Handy sits down with a16z's Jennifer Li and Matt Bornstein to explore the next chapter of data engineering — from the rise (and plateau) (https://round
Enabling Agents and Battling Bots on an AI-Centric Web
Arcjet (https://arcjet.com/) CEO David Mytton sits down with a16z partner Joel de la Garza to discuss the increasing complexity of managing who can access websites, and other web apps, and what they can do there. A primary challenge is dete
Giving New Life to Unstructured Data with LLMs and Agents
Instabase (https://instabase.com/) founder and CEO Anant Bhardwaj joins a16z Infra partner Guido Appenzeller to discuss the revolutionary impact of LLMs on analyzing unstructured data and documents (like letting banks verify identity and ap
Beyond Leaderboards: LMArena’s Mission to Make AI Reliable
LMArena (https://lmarena.ai/) cofounders Anastasios N. Angelopoulos, Wei-Lin Chiang, and Ion Stoica sit down with a16z general partner Anjney Midha to talk about the future of AI evaluation. As benchmarks struggle to keep up with the pace o
Building AI Systems You Can Trust
In this episode of AI + a16z, Distributional (https://www.distributional.com/) cofounder and CEO Scott Clark, and a16z partner Matt Bornstein, explore why building trust in AI systems matters more than just optimizing performance metrics. F
Who's Coding Now? AI and the Future of Software Development
In this episode of the a16z AI podcast, a16z Infra partners Guido Appenzeller, Matt Bornstein, and Yoko Li explore how generative AI is reshaping software development. From its potential as a new high-level programming abstraction to its cu
