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MCP Co-Creator on the Next Wave of LLM Innovation
In this episode of AI + a16z, Anthropic's David Soria Parra — who created MCP (Model Context Protocol) along with Justin Spahr-Summers — sits down with a16z's Yoko Li to discuss the project's inception, exciting use cases for connecting LLM
What Is an AI Agent?
In this episode of AI + a16z, a16z Infra partners Guido Appenzeller, Matt Bornstein, and Yoko Li discuss and debate one of the tech industry's buzziest words right now: AI agents. The trio digs into the topic from a number of angles, includ
Benchmarking AI Agents on Full-Stack Coding
In this episode, a16z General Partner Martin Casado sits down with Sujay Jayakar, co-founder and Chief Scientist at Convex (https://www.convex.dev/), to talk about his team’s latest work benchmarking AI agents on full-stack coding tasks. Fr
Automating Developer Email with MCP and Al Agents
In this episode of AI + a16z, Resend (https://resend.com/) founder and CEO Zeno Rocha sits down with a16z partner Yoko Li to discuss: • How generative AI — powered by agents and, now, MCP — is reshaping the email experience for developers,
The Future of Digital Workers
In this episode of AI + a16z, a16z Partner Joe Schmidt sits down with 11x CTO Prabhav Jain for an inside look at how AI-powered digital workers are reshaping sales and revenue operations. They discuss the evolution of agentic AI, the trade-
Building the Next Generation of Conversational AI
In this episode of AI + a16z, Sesame (https://www.sesame.com/) Cofounder and CTO Ankit Kumar joins a16z general partner Anjney Midha for a deep dive into the research and engineering behind their voice technology. They discuss the technical
Agent Experience: Building an Open Web for the AI Era
In this episode of AI + a16z, Netlify (https://www.netlify.com/) CEO and Cofounder Matt Biilmann joins a16z General Partner Martin Casado to explore how AI is reshaping web development — not just through faster code generation, but by funda
What DeepSeek Means for Cybersecurity
In this episode of AI + a16z, a trio of security experts join a16z partner Joel de la Garza to discuss the security implications of the DeepSeek reasoning model that made waves recently. It's three separate discussions, focusing on differen
Agents, Lawyers, and LLMs
In this episode of AI + a16z, Aatish Nayak, head of product at Harvey (https://www.harvey.ai/), sits down with a16z partner Kimberly Tan to share his experience building AI products for enterprises — including the legal profession — and how
Reasoning Models Are Remaking Professional Services
In this episode of AI + a16z, a16z partner Alex Immerman sits down with Hebbia (https://www.hebbia.com/)founder and CEO George Sivulka to discuss the potential for reasoning models and AI agents to supercharge knowledge-worker productivity
Data Management for Enterprise LLMs
In this episode of AI + a16z, Fivetran (https://fivetran.com) cofounder and CEO George Fraser and a16z partner Guido Appenzeller discuss how LLMs fit into the data management picture within large enterprises. In order to take advantage of a
From NLP to LLMs: The Quest for a Reliable Chatbot
In this episode of AI + a16z, a16z General Partner Martin Casado and Rasa (https://rasa.com/) cofounder and CEO Alan Nichol discuss the past, present, and future of AI agents and chatbots. Alan shares his history working to solve this probl
Best of the Year: Building AI Companies
A 2024 highlight reel, featuring founders sharing their insights, advice, and experiences building AI companies — from foundation-model labs to vertical applications. Topics include: • Building AI tools for developers • Getting into AI as a
Can AI Agents Finally Fix Customer Support?
In this episode of the AI + a16z podcast, Decagon (https://decagon.ai/) cofounder/CEO Jesse Zhang and a16z partner Kimberly Tan discuss how LLMs are reshaping customer support, the strong market demand for AI agents, and how AI agents give
REPLAY: Scoping the Enterprise LLM Market
This is a replay of our first episode from April 12, featuring Databricks VP of AI Naveen Rao and a16z partner Matt Bornstein discussing enterprise LLM adoption, hardware platforms, and what it means for AI to be mainstream. If you're unfam
Building Developers Tools, From Docker to Diffusion Models
In this episode of AI + a16z, Replicate (https://replicate.com/) cofounder and CEO Ben Firshman, and a16z partner Matt Bornstein, discuss the art of building products and companies that appeal to software developers. Ben was the creator of
The Best Way to Achieve AGI Is to Invent It
Longtime machine-learning researcher, and University of Washington Professor Emeritus, Pedro Domingos joins a16z General Partner Martin Casado to discuss the state of artificial intelligence, whether we're really on a path toward AGI, and t
Neural Nets and Nobel Prizes: AI's 40-Year Journey from the Lab to Ubiquity
In this episode of AI + a16z, General Partner Anjney Midha shares his perspective on the recent collection of Nobel Prizes awarded to AI researchers in both Physics and Chemistry. He talks through how early work on neural networks in the 19
How GPU Access Helps AI Startups Be Agile
In this episode of AI + a16z, General Partner Anjney Midha explains the forces that lead to GPU shortages and price spikes, and how the firm mitigates these concerns for portfolio companies by supplying them with the GPUs they need through
DisTrO and the Quest for Community-Trained AI Models
In this episode of AI + a16z, Bowen Peng and Jeffrey Quesnelle of Nous Research join a16z General Partner Anjney Midha to discuss their mission to keep open source AI research alive and activate the community of independent builders. The fo
Balancing AI Expertise and Industry Acumen in Vertical Applications
In this episode of AI + a16z, Ambience (https://www.ambiencehealthcare.com/) cofounder and chief scientist Nikhil Buduma joins Derrick Harris to discuss the nuances of using AI models to build vertical applications (including in his space,
AI, SQL, and the End of Big Data
In this episode of AI + a16z, a16z General Partner Jennifer Li joins MotherDuck (https://motherduck.com/) Cofounder and CEO Jordan Tigani to discuss DuckDB's spiking popularity as the era of big data wanes, as well as the applicability of S
The Researcher to Founder Journey, and the Power of Open Models
In this episode of the AI + a16z podcast, Black Forest Labs (https://blackforestlabs.ai/) founders Robin Rombach, Andreas Blattmann, and Patrick Esser sit down with a16z general partner Anjney Midha to discuss their journey from PhD researc
Why Computer Science Subsumed Biotech
In this episode, a16z General Partner Vijay Pande walks us through the past two decades of applying software engineering to the life sciences — from the Folding@Home project that he launched, through AlphaFold and more. He also discusses th
Democratizing Generative AI Red Teams
In this episode of the AI + a16z podcast, a16z General Partner Anjney Midha speaks with PromptFoo (https://www.promptfoo.dev/) founder and CEO Ian Webster about the importance of red-teaming for AI safety and security, and how bringing thos
Augmenting Incident Response with LLMs
In this episode of the AI + a16z podcast, Command Zero (https://www.cmdzero.io/) cofounder and CTO Dean de Beer joins a16z's Joel de la Garza and Derrick Harris to discuss the benefits of training large language models on security data, as
Scaling AI for the Coming Data Deluge
In this episode of the AI + a16z podcast, Anyscale (https://www.anyscale.com/) cofounder and CEO Robert Nishihara joins a16z's Jennifer Li and Derrick Harris to discuss the challenges of training and running AI models at scale; how a focus
ARCHIVE: The Dream of AI Is Alive in AlphaGo
In this archive episode from 2015, a16z's Sonal Chokshi, Frank Chen, and Steven Sinofsky discuss DeepMind's breakthrough AlphaGo system, which mastered the ancient Chinese game Go and introduced the public to reinforcement learning. Check o
Beyond Language: Inside a Hundred-Trillion-Token Video Model
In this episode of the AI + a16z podcast, Luma (https://lumalabs.ai/) Chief Scientist Jiaming Song joins a16z General Partner Anjney MIdha to discuss Jiaming's esteemed career in video models, culminating thus far in Luma's recently release
Developer Tool UX in the Age of Generative AI
In this episode, design engineer Alasdair Monk joins a16z's Yoko Li and Derrick Harris to discuss how generative AI is changing how developers — and the those building for developers — interact with the tools of their trade. Alasdair’s jour
