Endocrine Deep Dives

HNF1A MODY

Sonntag, 12. Juli 2026 · 22 min

MP3

Shownotes

This episode of Endocrine Deep Dives explores HNF1A MODY, or MODY 3, the most common form of monogenic diabetes. We examine its characteristic clinical presentation, marked by progressive beta cell dysfunction, a low renal threshold for glucose, and a lack of pancreatic autoantibodies. We discuss the importance of genetic testing to differentiate it from type 1 and type 2 diabetes and outline why low dose sulfonylureas are the preferred first line pharmacological treatment.

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