Latent Space: The AI Engineer Podcast

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1. 12. Feb.

   🔬 Beyond AlphaFold: How Boltz is Open-Sourcing the Future of Drug Discovery

   <p>This podcast features Gabriele Corso and Jeremy Wohlwend, co-founders of Boltz and authors of the Boltz Manifesto, discussing the rapid evolution of structural biology models from AlphaFold to their own open-source suite, Boltz-1 and Bol
   1 h 21
2. 10. Feb.

   ⚡️ Reverse Engineering OpenAI's Training Data — Pratyush Maini, Datology

   <p>Watch the full show on YouTube: https://www.youtube.com/watch?v=CSgjaC6y6Mk</p><p><a href="https://www.youtube.com/watch?v=CSgjaC6y6Mk">Full show notes and links</a></p>
   27 min
3. 6. Feb.

   The First Mechanistic Interpretability Frontier Lab — Myra Deng & Mark Bissell of Goodfire AI

   <p>From Palantir and Two Sigma to building Goodfire into the poster-child for actionable mechanistic interpretability, Mark Bissell (Member of Technical Staff) and Myra Deng (Head of Product) are trying to turn “peeking inside the model” in
   1 h 08
4. 4. Feb.

   ⚡️ Context Graphs: according to the authors — Jaya Gupta, Ashu Garg, Foundation Capital

   <p>Watch the full show on YouTube: https://www.youtube.com/watch?v=zP8P7hJXwE0</p><p><a href="https://www.youtube.com/watch?v=zP8P7hJXwE0">Full show notes and links</a></p>
   34 min
5. 28. Jan.

   🔬 Automating Science: World Models, Scientific Taste, Agent Loops — Andrew White

   <p>Editor’s note: Welcome to our new AI for Science pod, with your new hosts RJ and Brandon! See the writeup on Latent.Space (https://Latent.Space) for more details on why we’re launching 2 new pods this year. RJ Honicky is a co-founder and
   1 h 14
6. 27. Jan.

   ⚡️ Prism: OpenAI's LaTeX "Cursor for Scientists" — Kevin Weil & Victor Powell, OpenAI for Science

   <p>Watch the full show on YouTube: https://www.youtube.com/watch?v=W2cBTVr8nxU</p><p><a href="https://www.youtube.com/watch?v=W2cBTVr8nxU">Full show notes and links</a></p>
   36 min
7. 23. Jan.

   Captaining IMO Gold, Deep Think, On-Policy RL, Feeling the AGI in Singapore — Yi Tay

   <p>From shipping Gemini Deep Think and IMO Gold to launching the Reasoning and AGI team in Singapore, Yi Tay has spent the last 18 months living through the full arc of Google DeepMind’s pivot from architecture research to RL-driven reasoni
   1 h 32
8. 17. Jan.

   Brex’s AI Hail Mary — With CTO James Reggio

   <p>From building internal AI labs to becoming CTO of Brex, James Reggio has helped lead one of the most disciplined AI transformations inside a real financial institution where compliance, auditability, and customer trust actually matter. W
   1 h 13
9. 8. Jan.

   Artificial Analysis: Independent LLM Evals as a Service — with George Cameron and Micah-Hill Smith

   <p>Happy New Year! You may have noticed that in 2025 we had moved toward YouTube as our primary podcasting platform. As we’ll explain in the next State of Latent Space post, we’ll be doubling down on Substack again and improving the experie
   1 h 18
10. 6. Jan.

    [State of Evals] LMArena's $1.7B Vision — Anastasios Angelopoulos, LMArena

    <p>We are reupping this episode after LMArena announced their fresh Series A (https://www.theinformation.com/articles/ai-evaluation-startup-lmarena-valued-1-7-billion-new-funding-round?rc=luxwz4), raising $150m at a $1.7B valuation, with $3
    24 min