The Dark Side of Human Optimisation: Nicotine, Peptides, NAD+ & the Enhanced Games | Longevity Doctor Explains

This week I'm joined by Dr Jack Kreindler, physician, healthtech entrepreneur and founder of WellFounded Health and the Centre for Health and Human Performance, and someone who has spent 26 years asking one of the most important questions in medicine, what does it mean to not just fix disease, but to truly enhance human life?
We explore longevity, prevention, performance and what the most advanced medicine in the world is learning about how to live well for longer.
Dr Jack Kreindler qualified in medicine and physiology from University College London and spent a decade as an emergency physician before founding the Centre for Health and Human Performance in Harley Street in 2007. He is an honorary clinical research fellow at Imperial College London, founder and CEO of WellFounded Health and a leading voice on healthy longevity, human performance and the future of medicine. He has worked with elite athletes, extreme environment explorers and high performance executives across the world.
What we explore together:
• Why medicine is shifting from fixing disease to enhancing physiology and what that means for you

• What burning the candle at three ends is actually doing to your brain and body

• Why cadence is king and how everything in nature and biology moves in waves

• What the most advanced health testing actually looks like and what it tells us

• The truth about longevity supplements, peptides and biohacking and who they actually work for

• Why your history is still the most powerful diagnostic tool ever invented

• What it really means to enhance a human life rather than just extend it

Love, Sarah Ann 💛
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Chapters
00:00 Introduction
02:59 How Jack's view of medicine changed over 26 years
05:58 Burning the candle at three ends and what it costs you
09:04 Why cadence is king in biology and life
12:00 What a prevention first approach to health looks like
18:00 Your history from one cell to 38 trillion
21:02 What advanced health testing actually reveals
30:00 Hormones, menopause and andropause
33:02 Cardiovascular risk and how to assess it properly
36:00 Brain health, dementia risk and what you can do now
39:07 The gut microbiome and its role in everything
42:00 Extreme environments and what they teach us about health
45:08 Elite sport science applied to everyday health
48:00 The longevity space and what the evidence actually shows
51:07 Peptides, supplements and biohacking
54:06 What works, what doesn't and how to know the difference
57:07 AI and the future of personalised medicine
66:04 The bell shaped curve and why nothing works for everyone
69:08 What enhancing a human life really means
72:00 Not dying dull and what Jack has learned
75:02 Final thoughts on living well and being well