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Night Science

von Itai Yanai & Martin Lercher

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Where do ideas come from? In each episode, scientists Itai Yanai and Martin Lercher explore science's creative side with a leading colleague. New episodes come out every second Monday.

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  1. 89 | Woods Hole Night Science!

    What if an intensive science course wasn't primarily about learning techniques or producing results, but about learning how to think like a scientist? To explore that question, Itai visited the legendary Marine Biological Laboratory in Wood

  2. 88 | How AI dreams up new science – with Jure Leskovec

    What happens when AI starts doing science? We talk with Stanford computer scientist Jure Leskovec about AI agents that find patterns in large datasets, come up with hypotheses and try to kill them with more data, enduring the tedious work h

  3. 87 | On the joys of being a young scientist

    What can early-career scientists teach us about creativity? For this special episode, we talked to PhD students and postdocs about their creative processes. They told us about finding scientific ideas in art museums, sketching on whiteboard

  4. 86 | From punchlines to discovery – Sarah Adelman

    What can comedy teach us about scientific discovery? With stand-up comedian and former research scientist Sarah Adelman, we discuss the surprising parallels between jokes and discoveries. Sarah shares her path from public health research to

  5. 85 | How laziness invites discovery – Robert Root-Bernstein

    Professor Robert Root-Bernstein has not only made many scientific discoveries, but has also written extensively about the creative process, including in Sparks of Genius (with Michele Root-Bernstein) and in his latest book, The Arts of Emin

  6. 84 | Every scientist is an artist – Lois Hetland

    Professor Lois Hetland, the former chair of art education at the Massachusetts College of Art, joins us to ask: what do artists and scientists truly share? We explore the striking parallels between artistic practice and scientific discovery

  7. 83 | How science is secretly driven by analogy – Melanie Mitchell

    Melanie Mitchell is a professor at the Santa Fe Institute and a leading thinker on artificial intelligence, analogy, and abstraction. She reflects on how analogy quietly drives creativity and scientific discovery even in the most rigorous f

  8. 82 | On being alone together – Amy Shyer & Alan Rodrigues

    Amy Shyer & Alan Rodrigues co-direct the Laboratory of Morphogenesis at Rockefeller University. They are also married. Together, we reflect on what it means to think creatively in biology. Amy and Alan discuss the importance of challenging

  9. 81 | How to find your way by getting lost – Marina Dubova

    It’s surprising that for centuries, scientists have left the study of how to do science largely to non-scientists. Not anymore – thanks to the young field of cognitive epistemology. In this episode, we discuss the exciting – and surprising

  10. 80 | Why greatness cannot be planned with Kenneth Stanley

    Ken Stanley is a highly regarded researcher in machine learning and artificial intelligence. After leaving his professorship at the University of Central Florida, he cofounded Geometric Intelligence (now Uber AI Labs), and he is now Senior

  11. 79 | Maria Leptin and creativity in grant writing

    Maria Leptin is the President of the ERC, the European Research Council, and Professor of genetics at the University of Cologne. In this episode, Maria describes her own path as one driven by observation and curiosity rather than long-term

  12. 78 | Stephen Nachmanovitch on free play and chivalry

    Stephen Nachmanovitch is a musician celebrated for his free improvisations, and an educator whose books Free Play and The Art of Is have become classics on the creative process. With his training as an ecologist and his PhD in the history o

  13. 77 | Akiko Iwasaki and the art of creativity maintenance

    Akiko Iwasaki, a Yale professor and Howard Hughes Investigator, was named one of Time Magazine’s 100 most influential people in 2024. Together, we reflect on how diverse backgrounds enrich research, allowing people to discover different thi

  14. 76 | Can Google’s Co-scientist project give scientists superpowers?

    To answer this question, we speak with Dr. Alan Karthikesalingam and Vivek Natarajan from Google DeepMind about their groundbreaking AI co-scientist project. Beyond their work at Google, Alan is an honorary lecturer in vascular surgery at I

  15. 75 | Eve Marder and how Recipe Science ruins creativity

    Professor Eve Marder is a pioneering neuroscientist at Brandeis University. Drawing on decades of work with a small neural circuit in lobsters, she describes how discovery often emerges from intuition, puzzlement, and the courage to follow

  16. 74 | Martin Schwartz and the importance of stupidity in science

    Martin Schwartz, a professor at Yale, is known for his work on integrins and his influential essay “The importance of stupidity in scientific research”. He emphasizes that while learning science makes you feel smart, true scientific discove

  17. 73 | Ethan Mollick and a million Einsteins in a server

    With Ethan Mollick, professor at Wharton and author of the bestselling “Co-Intelligence”, we explore how generative AI tools like ChatGPT can enhance scientific creativity. Ethan emphasizes that AI excels at idea generation through sheer vo

  18. 72 | David Baker and the lab's communal brain

    David Baker, who was awarded the 2024 Nobel Prize in Chemistry for designing novel proteins with AI, is a professor at the University of Washington. In this episode, he explains how he socially engineers his lab’s "communal brain", where al

  19. 71 | Victor Ambros and the unique ways we perceive wonder

    Victor Ambros, newly awarded the Nobel Prize for his discovery of microRNA, is a developmental biologist at the University of Massachusetts Medical School. In this episode, we explore improvisational science – the dynamic, collaborative pro

  20. 70 | Meghan O’Rourke on being the artist and their caretaker

    Meghan O'Rourke, acclaimed author of The Invisible Kingdom, poet, and Yale professor, joins us to explore the parallels between creative writing and scientific discovery. She describes how deep immersion in a project attracts unexpected ins

  21. 69 | Keith Yamamoto and the freedom to fail

    Keith Yamamoto, professor and science policy leader at UCSF, discusses with us how modern science became trapped in a system that discourages creative risk-taking. Keith contrasts academia's fear of failure with Silicon Valley's acceptance

  22. 68 | Peter Godfrey-Smith and middle class science

    Peter Godfrey-Smith, a Professor of the Philosophy of Science at the University of Sydney, explores with us the differences between creativity in science and philosophy. While philosophers speculate unconstrainedly, scientists must balance

  23. 67 | A hypothesis is a liability

    In this episode, Itai and Martin delve into the interplay between hypothesis-driven and exploratory research, drawing on insights from past guests of the Night Science Podcast. They discuss how being focused on a single hypothesis can preve

  24. 66 | Michael Fischbach and the scientific decision tree

    In this episode, Stanford professor Michael Fischbach discusses insights from his course on how to choose meaningful research problems. Highlights include: - Invest time in problem selection: Spend more time upfront selecting the right rese

  25. 65 | James Kaufman and the art of creativity maintenance

    James Kaufman, Professor of Educational Psychology at the University of Connecticut, discusses the psychological underpinnings of creative thinking with Itai & Martin. Together, we delve into the complex nature of creativity, exploring its

  26. 64 | Robert Weinberg and the perils of being a Fachidiot

    MIT's Bob Weinberg is perhaps the world's most prominent cancer researcher. In this episode, Bob emphasizes that true innovation often comes from blending ideas from different fields – a synthesis that transcends the boundaries of one's pri

  27. 63 | Manu Prakash and how the discovery changes you

    Manu Prakash is a professor of bioengineering at Stanford University, asking biological questions with insights from physics. His most widely known contribution is the FoldScope, a $1-microscope made from paper and a lens – 2 million copies

  28. 62 | Dianne Newman and the visceral and intentional sides of science

    Dianne Newman – a molecular microbiologist at CalTech – is a professor both in Biology and Geology. In this episode, she encourages young scientists to pursue questions to which they have a visceral connection, rather than following popular

  29. 61 | Tina Seelig on what to do with a really bad idea

    Tina Seelig is Executive Director of the Knight-Hennessy-Scholars at Stanford University. She is widely known for teaching creativity courses and workshops with an entrepreneurial focus. In this episode, Tina emphasizes the importance of li

  30. 60 | Venki Ramakrishnan and the secrets of doing science over tea

    Venki Ramakrishnan shared the 2009 Nobel Prize in Chemistry for uncovering the structure of the ribosome. He runs a lab at the MRC Laboratory of Molecular Biology in Cambridge, England. In this episode, Venki emphasizes the importance of en

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