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Night Science

von Itai Yanai & Martin Lercher

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  1. 59 | Jennifer Oyler-Yaniv and the point of creative frustration

    Jennifer Oyler-Yaniv is a professor working on the immune system at Harvard’s Medical School. In this episode, we discuss with her how she teaches creativity in her course for PhD students. We explore the emotional roller coaster ride of re

  2. 58 | Guy Yanai on Pentimenti

    Guy Yanai is a painter whose work is displayed in many public and private collections across the US, Europe, and Asia, including, for example, the Tel Aviv Museum of Art. His distinctive painting style blends modernist, abstract tendencies

  3. 57 | George Church and shooting for the stars

    George Church, professor of genetics at Harvard Medical School, leads a large research group at the Wyss Institute for Biologically Inspired Engineering. A pioneer in the fields of personalized genomics and synthetic biology, he has co-foun

  4. 56 | Magdalena Zernicka-Goetz lights a candle for science

    Prof. Magdalena Zernicka-Goetz directs research labs at both CalTech in the US and the University of Cambridge in England. Magdalena is one of the world’s leading developmental biologists, who has been recognized by the 2023 Ogawa-Yamanaka

  5. 55 | Isaac Newton and a new kind of science

    Night Science – coming up with novel ways to interpret the physical world – is as old as philosophy. In contrast, Day Science – empirical evidence as the sole argument for truth – was invented only in the 1700s, championed by the groundbrea

  6. 54 | Bo Xia and a tale of tails

    Bo Xia is a Junior Fellow at Harvard and a Principal Investigator at the Broad Institute. During his PhD with Itai, he suffered a painful tailbone injury that led to an obsession with this vestigial organ and its origins in human evolution.

  7. 53 | Todd Golub and bottom-up creativity

    Prof. Todd Golub, the Director of the Broad Institute of MIT and Harvard, has made important contributions to cancer research. In this episode, he argues that creativity is the greatest hallmark of a successful scientist, and he tells us ab

  8. 52 | Sean B. Carroll – he told some good stories

    Sean Carroll is a world-renowned scientist, author, educator, and an Oscar-nominated film producer. Sean sees storytelling as the key to all he does. Similar to how musicians get inspiration by listening to other people’s music, Sean attrib

  9. 51 | Nigel Goldenfeld and the jazz of impossible problems

    Nigel Goldenfeld is the Chancellor's Distinguished Professor in Physics at the University of California at San Diego. In this episode, he talks with us about how research is an art form, and how he tries to help graduate students make the t

  10. 50 | It takes two to think

    Despite the variety of creative approaches practiced by different scientists, one tried-and-true though often overlooked — trick for generating new ideas stands out. It may sound trivial, yet it is as reliable as it is simple: talk to someo

  11. 49 | Rich White on living on the edge cases

    Rich White studies cancer as a professor at Oxford University. Rich is not only a brilliant physician-scientist but also a great friend of Itai Yanai, one of the two Night Science hosts. In this episode, Rich talks about how often the proce

  12. 48 | Carolyn Bertozzi and a long game called science

    Carolyn Bertozzi is a Professor at Stanford University. In 2022, she was awarded the Nobel Prize in Chemistry. In this episode we talk about how the process of science is unstructured, so you don’t know when and where the next idea is going

  13. 47 | Stephen Quake and the Creative Network

    Stephen Quake is a Stanford University professor and the Head of Science at the Chan Zuckerberg Initiative (CZI). Among his many inventions are DNA sequencing methods for non-invasive prenatal testing. In this episode, Steve tells us about

  14. 46 | John Mattick and doing what your mother taught you

    John Mattick is Professor of RNA Biology at the University of New South Wales in Sydney, Australia. For decades, he has been on a mission to show that the large portions of the human genome that many scientists consider useless "junk" inste

  15. 45 | Peter Ratcliffe on being the Master of Daydreams

    Peter J. Ratcliffe shared the 2019 Nobel Prize in Physiology or Medicine for his work on oxygen sensing in animal cells. He directs research institutes in London and Oxford. In this episode, he reveals the interplay between dissociation – d

  16. 44 | Christina Curtis and keeping the faith in the process

    Christina Curtis is a Professor of Medicine and the Director of Artificial Intelligence and Cancer Genomics at Stanford University’s Cancer Institute. Among her many achievements is the conception of the “Big Bang Theory” of tumor biology.

  17. 43 | Daniel Dennett’s intuition pumps

    Daniel Dennett, Professor at Tufts University, may be the most important living philosopher, tackling the biggest questions around: what is consciousness, do we have free will, how does evolutionary adaptation occur? In this episode, Dan te

  18. 42 | Howard Stone on how to tilt your head for discovery

    Howard Stone is a Professor of Engineering at Princeton. His research explores how fluid dynamics can help to understand diverse systems, from bacterial biofilms to the earth’s interior. In this episode, Howard explains how a lot of importa

  19. 41 | Prisca Liberali and the junkies of discovery

    Prisca Liberali is a senior group leader at the Friedrich Miescher Institute for Biomedical Research in Switzerland. In this episode, Prisca tells us how her creative thinking thrives on recursive thinking – going deeper and deeper into a p

  20. 40 | Tom Mullaney & Chris Rea on giving thanks to bias

    Tom Mullaney is a Professor of History at Stanford University and the Kluge Chair in Technology and Society at the Library of Congress, and Chris Rea is a Professor of Asian Studies at the University of British Columbia. In 2022, Tom and Ch

  21. 39 | Bonnie Bassler and living on the edge in a nerdy kind of way

    Bonnie Bassler is the Chair of the Molecular Biology Department at Princeton. In this episode, Bonnie talks about her passion for scientific inquiry, creativity, mentorship, and how the journey of discovery is about asking the right questio

  22. 38 | Yukiko Yamashita, the queen of analogies

    Yukiko Yamashita is a biology professor at MIT and an investigator at the Howard Hughes Medical Institute. Yukiko’s research is amazingly broad, perhaps because she often only realizes at the end of a project which question she was asking b

  23. 37 | Stephen Wolfram is the Worldly Scientist

    Can you think of another big company CEO that does basic science? Stephen Wolfram is the CEO of Wolfram Research – the company that developed Mathematica and Wolfram Alpha – but most fundamentally he has a deep commitment to figuring out th

  24. 36 | Laurence Hurst and the slime mold model of discovery

    Laurence Hurst is a professor of Evolutionary Genetics and the founding Director of the Milner Centre for Evolution at The University of Bath. Martin actually learned biology from Laurence as a postdoc, and he still likes to quote Laurence’

  25. 35 | Edith Heard and the feeling for the system

    Edith Heard is a Professor at the Collège de France and the Director General of Europe’s “CERN for biologists”, the European Molecular Biology Lab (EMBL). In this episode, Edith explains how she gets ideas when she’s out of her comfort zone

  26. 34 | Ewan Birney and the battle scars of discovery

    Ewan Birney is the deputy director general of the European Molecular Biology Lab (EMBL) and co-director of the European Bioinformatics Institute. In his research, Ewan combines his training in biochemistry with computer science, which made

  27. 33 | Paola Arlotta and science as a walk in the dark woods

    Paola Arlotta is a developmental neurobiologist and a professor at Harvard. She studies how the most complex organ in the human body (in the world? in the universe maybe?) comes to be: the brain (!). How does it develop from just a bunch of

  28. 32 | Marty Martin and Art Woods on science podcasting

    In this special, we talk about podcasting with the two hosts of the Big Biology Podcast (https://www.bigbiology.org/), Marty Martin – professor of disease ecology at the University of South Florida – and Art Woods – professor of physiologic

  29. 31 | Alfred Russel Wallace and night science by candlelight

    What was the creative process of Alfred Russel Wallace? In this séance, we channel the legendary self-taught evolutionary biologist, founder of the field of biogeography, and co-discoverer of natural selection. Mr. Wallace (as he insists to

  30. 30 | Zak Kohane and the abstraction of data

    Isaac (Zak) Kohane is the Chair of the Department of Biomedical Informatics at Harvard Medical School. In this episode, Zak talks with us about how medicine, at its core, is information processing. But in medical data science, one has to un

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