Methylene Blue & Mitochondria: How This Compound Fights Alzheimer's and Brain Aging

I'm excited to share my conversation with Dr. Scott Sherr, where we dive deep into methylene blue - a compound you've probably seen all over social media lately (those blue tongues!). As someone whose primary research focuses on Alzheimer's disease, I was fascinated to explore the science behind this molecule that dates back to the 1870s and was actually the first drug registered with the FDA in 1897.

The most fascinating insight for me was learning how methylene blue can serve as an electron acceptor in our mitochondria - essentially functioning as a substitute for oxygen when our cells are under stress. This explains why it shows promise for everything from traumatic brain injury to cognitive enhancement and even as a potential alternative to stimulant medications.

If you're interested in optimizing brain performance, understanding mitochondrial health, or simply curious about this blue compound that's suddenly everywhere, this episode provides both the scientific foundation and practical applications you need.

Subscribe to The Neuroscience Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey.

Sponsors
A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts:

Hone Health – Take control of your hormones with at-home testing designed specifically for men. Get personalized insights and expert guidance to optimize your health and performance. Learn more at: honehealth.com

Momentous – Science-backed supplements trusted by elite athletes and experts. Whether you’re looking to improve recovery, performance, or overall wellness, Momentous has you covered. Use code NEURO for 20% off your order: livemomentous.com/neuro

Troscriptions – Unlock your cognitive potential with precision-dosed nootropics developed by medical experts. Whether you need more focus, clarity, or energy, Troscriptions offers innovative solutions.
- Get 10% off: troscriptions.com/NEURO
- troscriptions.com/discount/NEUROMAIL?utm_sourc…

Timestamps
00:00 Introduction
02:30 Methylene Blue's Role in Neurotransmitter Regulation
07:54 Mitochondrial Health and Methylene Blue
17:02 Methylene Blue and Modern Health Challenges
25:27 Methylene Blue in Hypobaric and Hyperbaric Environments
29:47 Understanding Hyperbaric Oxygen Therapy
32:27 Methylene Blue: A Mitochondrial Rescue
36:52 Bioavailability of Methylene Blue
42:17 Dosing and Applications of Methylene Blue
47:46 Combining Methylene Blue with Other Treatments
54:02 Conclusion and Further Resources
The Neuro Athletics Newsletter (bit.ly/3ewI5P0)
Instagram (instagram.com/louisanicola_): @louisanicola_
Twitter (twitter.com/louisanicola_) : @louisanicola_
YouTube (youtube.com/c/LouisaNicola): @Louisa Nicola

The Neuro Experience Podcast is proud to have hosted: Dr Andrew Huberman, Dr Gabrielle Lyon, Dr Layne Norton, Thomas DeLauer, Shawn Stevenson, Dr. Rocio Salas-Whalen, Saad Alam, Uma Naidoo, Dr. Lanna Cheuck, Angela Lee Pucci, Jillian Turecki, Dr. Jordan Feigenbaum, Dr. Darren Candow, Dr. Sue Varma, Evy Poumpouras, Dr Casey Means, Renee Deehan, Dr Chris Palmer, Dr Charles Brenner, Dr Joe Zundell, Dr Ray Dorsy, Dr Dale Bredeson, Dr. Ben Bikman

Learn more about your ad choices. Visit megaphone.fm/adchoices