Anmelden

This Week in AI

No One Likes Any of Sam Altman’s 3 AI Endgames | TWiAI E36

Donnerstag, 22. Oktober 2026 · 1 h 14

MP3

Shownotes

This Week In AI is made possible by PayPal:paypal.launch.co

Today’s show:
Sam Altman told OpenAI staff that there are only three ways for AI regulation to go: an international watchdog, every lab merging into one CERN-style entity, or one company getting so powerful that they “melt everyone else’s GPUs.”
Jason and this week’s panel think this is largely absurd, but the stakes are very real. Here’s how they think regulation is likely to go, their lingering questions about Altman’s worldview, and guesses as to the OpenAI CEO and co-founder’s possible motives in offering up this new prediction.
Plus:
The US Government banned DeepSeek from every federal computer… What has them so spooked, and how does this impact US companies?
Did ElevenLabs steal a YouTuber’s voice or is it all a misunderstanding.
Why Chinese labs are ordering more chips than Nvidia can even produce.
And more!

Guests
Jaleh Rezaei on X:x.com/jalehr
Mutiny:mutinyhq.com
Alex Cheema on X:x.com/alexocheema
EXO Labs:exolabs.net

Relevant Links
DHS order banning DeepSeek (Federal Register):federalregister.gov/documents/2026/10/20/2026-…
DeepSeek’s DeepInfer on GitHub:github.com/deepseek-ai/DeepInfer
Sam Altman’s 3 AI Endgames (The Information):theinformation.com/articles/altman-describes-t…
Chris Williamson’s ElevenLabs allegation (YouTube):youtube.com/watch?v=lxDNHLgWInU
Archer voice actor response (YouTube):youtube.com/watch?v=C33AWhQwL1I
Databricks CEO Ali Ghodsi on recursive self improvement (a16z):a16z.com/podcast/databricks-ceo-on-ai-pacing-c…
Looking for backdoors in Jane Street LLMs (LessWrong):lesswrong.com/posts/a98MFPmqH54J2ayBn/looking-…
Exo turns 4 Mac Studios into a 4.8TB/s AI cluster (AlphaSignal):alphasignal.ai/news/exo-turns-four-mac-studios…

Timestamps:
Cold Open / Show Intro
PayPal - Pay zero processing fees on your first $100K in eligible PayPal payment volume. Learn more at paypal.launch.co
How much hardware it takes to run local AI models
DHS orders DeepSeek out of federal systems
Why enterprise clients are uneasy about Chinese models
Could an open-source model "phone home" to Beijing?
Why enterprises are much more price sensitive about AI tools
Are Sam Altman's AI endgame theories "deranged"?
Why the major labs want more regulations
The ElevenLabs Archer controversy continues
Who actually owns the rights to your voice?
"Substack for AI Models"
China needs more chips than Nvidia can make
Are enterprises running more local models?

Subscribe to our newsletters on Substack:
TWiST:twistartups.substack.com
TWiAI:thisweekinai.ai
TWiVC:thisweekinvc.substack.com

Subscribe to This Week in Startups on Apple:rb.gy/v19fcp
Follow Lon:
X:x.com/lons
Follow Jason:
X:twitter.com/Jason
LinkedIn:linkedin.com/in/jasoncalacanis
Check out all our partner offers:partners.launch.co
Great TWIST interviews:Will Guidara, (youtu.be/pvJa2pzuXWQ)Eoghan McCabe (youtu.be/9dHN4YFkgv4),Steve Huffman (podcasts.apple.com/us/podcast/reddit-ceo-steve…),Brian Chesky (podcasts.apple.com/ca/podcast/airbnb-ceo-brian…),Bob Moesta, (youtu.be/y2UMzSqX94Q)Aaron Levie (podcasts.apple.com/ca/podcast/box-ceo-aaron-le…),Sophia Amoruso (podcasts.apple.com/ca/podcast/sophia-amoruso-o…),Reid Hoffman (podcasts.apple.com/ca/podcast/reid-hoffman-on-…),Frank Slootman (podcasts.apple.com/ca/podcast/snowflake-ceo-fr…),Billy McFarland (podcasts.apple.com/ca/podcast/billy-mcfarland-…)

Follow TWiST:
Twitter:twitter.com/TWiStartups
YouTube:youtube.com/thisweekin
Instagram:instagram.com/thisweekinstartups
TikTok:tiktok.com/@thisweekinstartups
Substack:twistartups.substack.com

Anmelden oder registrieren

Jetzt

0:00 / 0:00