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This Week in Virology

von Vincent Racaniello

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  1. TWiV 1314: Clinical update with Dr. Daniel Griffin

    TWiV 1314: Clinical update with Dr. Daniel Griffin April 17, 2026 In his weekly clinical update, Dr. Griffin and Vincent Racaniello are dismayed but not surprised by poll results suggesting most Americans doubt vaccine safety, that the head

  2. TWiV 1313: Maybe they're all dementia vaccines

    TWiV reviews evidence that influenza standard and high-dose vaccines reduce risk of Alzheimer’s dementia, and spread of deltaviruses by a viral Trojan horse mechanism. Hosts: Vincent Racaniello (https://en.wikipedia.org/wiki/Vincent_Racanie

  3. TWiV 1312: Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello are aghast at the CDC’s decision to no longer test for rabies and mpox and the revised charter for its the advisory committee on immunization practices, an outbreak of E. col

  4. TWiV 1311: Jayhawks go viral

    Vincent visits the University of Kansas and speaks with Tony Fehr, Robin Orozco, Juergen Richt and Rob Unckless about their careers and the research ongoing in their laboratories. Host: Vincent Racaniello Guests: Tony Fehr, Robin Orozco, Ju

  5. TWiV 1310: Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello cover if the “five-second” rule for things that fall on the floor apply to surgical equipment, an outbreak of E. coli illness caused by raw cheese before Dr. Griffin then dee

  6. TWiV 1309: Maybe they're all cancer vaccines

    TWiV explains why human papillomavirus vaccine-induced immunity can block infection, unlike all other vaccines, and how respiratory viral infections such as COVID and influenza prime accelerated lung cancer growth. Hosts: Vincent Racaniello

  7. TWiV 1308: Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello talk about the resignation of a member of the advisory committee for immunization practices and the irony of his rationale that a judge slandered him, vaccinating dairy cattl

  8. TWiV 1307: My heart breaks for flu

    TWiV reviews the structural basis for Rep-mediated adeno-associated virus DNA genome packaging, how influenza virus-infected myeloid cells travel to the heart and infect cardiomyocytes, leading to IFN-fueled heart damage. Hosts: Vincent Rac

  9. TWiV 1306: Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello chat about death of water fowl on Long Island, ‘renaming’ of the FDA adverse event monitoring system, lawsuits against RFK Jr and HHS for illegal changes in routine immunizat

  10. TWiV 1305: Lab leak idea called on the carpet

    TWiV introduces sunshine virus of carpet pythons and its effect snakes after experimental infection, and development of a new tool to distinguish between naturally ocurring outbreaks and those that arise from lab accidents. Hosts: Vincent R

  11. TWiV 1304: Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the global spread of the ‘eradicated’ poliovirus, the suggestion of RFK’s autocratic ability to change vaccine policy and the ‘resignation’ for the second time of CBE

  12. TWiV 1303: Overachieving vaccines

    TWiV reviews an association between shingles vaccination and slower biological aging, and how mucosal immunization in mice provides protection against disease caused by diverse viruses and bacteria. Hosts: Vincent Racaniello (https://en.wik

  13. TWiV 1302: Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello talk about the health misconceptions that RFK Jr continues to perpetuate and how to combat them, first cases of highly pathogenic influenza in the California elephant seal po

  14. TWiV 1301: Lost in giant virus translation

    TWiV reviews lymphocytic choriomeningitis virus seroprevalence among urban pregnant women and newborns in Philadelphia, and a functional translation initiation complex encoded in the genome of giant viruses that drives synthesis of viral st

  15. TWiV 1300: Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss several states and the governor of Pennsylvania suing HHS over changes in the childhood vaccination schedule, the vaccine derived type 2 poliovirus outbreak in Pakist

  16. TWiV 1299: Moth balls and blood clots

    TWiV explains how vaccine-induced thrombotic thrombocytopenia develops from antibodies to adenovirus and somatic hypermutation, and castration by a viral protein tyrosine phosphatase that targets a host cell cycle checkpoint protein. Hosts:

  17. TWiV 1298: Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss reversal of last week’s no review decision on a flu mRNA vaccine by Vinjay Prasad, appointment of Jay Bhattacharya as CDC director, no experience required, and alread

  18. TWiV 1297: Spillover squirrel

    TWiV explains the observation that filamentous virions act as non-infectious interfering particles to modulate papillomavirus infection, and transmission of monkeypox virus from fire-footed rope squirrels to sooty mangabeys. Hosts: Vincent

  19. TWiV 1296: Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello are shocked by recent events, including Dr. Oz’s appeal for measles vaccination, Vinjay Prasad’s unilateral rejection of Moderna’s mRNA influenza vaccine application, and the

  20. TWiV 1295: Are YOU willing to take one for the team?

    TWiV reviews a survey conducted in Cambodia's floating villages to explore measles vaccination perceptions and willingness to consider novel vaccination approaches, and how a prophage defends against an infecting phage. Hosts: Vincent Racan

  21. TWiV 1294: Clinical update with Dr. Daniel Griffin

    In his weekly clinical update during Ground hog week, Dr. Griffin and Vincent Racaniello are back to discuss the measles outbreak in South Carolina, American Academy of Pediatrics vaccine recommendations and shingles vaccine and the reducti

  22. TWiV 1293: The enemy of your parasite is your friend

    TWiV reviews the finding in Sweden that immunization against cervical cancer with human papillomavirus vaccine also protects the non-immunized, and methyl salicylic acid as a key volatile molecule that attracts parasitoid wasps to rice and

  23. TWiV 1292: Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss with disgust the decline and fall of American public health and the rise of “only me” when highlighting completion of the US withdrawal from the WHO and possibility o

  24. TWiV 1291: A foot in the door for cytomegalovirus

    TWiV explains emergence of a neurovirulent double recombinant from the ‘improved’ nOPV2 in Uganda, and efficiency of viral entry determined whether cells are latently or lytically infected with cytomegalovirus. Hosts: Vincent Racaniello (ht

  25. TWiV 1290: Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss screwworm, how the shingles vaccination slows biological aging (for all of you who want to reset ‘the clock’ and live forever…..you know who you are Musk, Bezos) and

  26. TWiV 1289: Building a better hepatitis B trap

    TWiV explains how the dengue virus protein NS1 alters Aedes aegypti midgut permeability and favors virus dissemination, and achieving a complete hepatitis B virus cure in chronic hepatitis B virus-infected humanized mice by using a capsid a

  27. TWiV 1288: Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello are bewildered and dismayed by RFK Jr’s announced changes in the routine childhood immunization schedule, though not unpredicted, and highlight the science and evidence which

  28. TWiV 1287: Ancient herpesviruses and modern dementia

    TWiV explain the tracing of 2500 years of human betaherpesvirus 6A and 6B diversity through ancient human DNA, the effect of shingles vaccination at different stages of the dementia disease course. Hosts: Vincent Racaniello (https://en.wiki

  29. TWiV 1286: Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Dr. Griffin and Vincent Racaniello are bewildered and dismayed by RFK Jr’s announced changes in the routine childhood immunization schedule, though not unpredicted, and highlight the science and evidence which

  30. TWiV 1285: Encapsidating viruses 2025

    TWiV reviews compelling virology themes for 2024, as heard in our 98 episodes, including 22 guests. Hosts: Vincent Racaniello (https://en.wikipedia.org/wiki/Vincent_Racaniello) and Kathy Spindler Subscribe (free): Apple Podcasts, RSS, email

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