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This Week in Virology

von Vincent Racaniello

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This Week in Virology is a netcast about viruses - the kind that make you sick.

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  1. TWiV 1371: How to Bat Away Marburg Virus

    TWiV discusses an outbreak of H5N1 influenza viruses in Utah farmed mink, and divergent species-specific antiviral responses in Marburg virus infected cells from reservoir bats and humans. Hosts: Vincent Racaniello (https://en.wikipedia.org

  2. TWiV 1370: Clinical Update with Dr. Daniel Griffin

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello are distressed by the continued upheaval of leadership at the CDC, recent news of H5 highly pathogenic influenza virus found on mink farms in Utah and in the polar bear po

  3. TWiV 1369: Florida Model Makes Measles Great Again

    TWiV explains projected effects of removing school-entry vaccination requirements on measles transmission in Florida and evidence that HLA class I escape drives the evolution of SARS-CoV-2 in human populations. Hosts: Vincent Racaniello (ht

  4. TWiV 1368: Clinical Update with Dr. Daniel Griffin

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello are discouraged by the continuous attack on vaccines especially the birth dose of the hepatitis B virus vaccine, effects of the 2026 changes in immunization schedule, the

  5. TWiV 1367: Turning Off Hepatitis B Virus Without Cutting its DNA

    TWiV explains a study which shows that influenza A virus infection induces immune dysregulation in the placenta and fetus without vertical transmission in nonhuman primates, and development of an epigenetic silencer therapy to transcription

  6. TWiV 1366: Clinical Update with Dr. Daniel Griffin

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello are crestfallen to learn of the 6th measles death in Pennsylvania and more than 9000 deaths from Ebola, an enterovirus/Coxsackievirus outbreak at the University of Pennsyl

  7. TWiV 1365: Andes Virus Up Close

    TWiV travels to Porto, Portugal for the annual meeting of the European Society for Clinical Virology, where he speaks with Catherine and Corinne about their work on the Andes virus outbreak on the MV Hondius. Host: Vincent Racaniello Guests

  8. TWiV 1364: Clinical Update with Dr. Daniel Griffin

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello discuss their continuing struggle to understand the ongoing outbreak of cyclospora, decimation of US public health including 30% or greater loss of personnel from the CDC,

  9. TWiV 1363: A Cauldron of Bats

    TWiV explains a study testing how 16 hypothesized social and environmental drivers impact disease outbreaks, concluding that infectious disease spillover and emergence are multi-causal, and that no one-size-fits-all strategy can prevent epi

  10. TWiV 1362: Clinical Update with Dr. Daniel Griffin

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello continue their ongoing exasperation over 5 deaths in Pennsylvania associated with measles infections, the absurdity of RFK Jr.’s statement that AI is better informed than

  11. TWiV 1361: Ancient Viral Sword and Shield

    TWiV explains discovery of a previously unknown mechanism of RNA-guided DNA recognition for genetic control that possibly predates the emergence of CRISPR pathways, and the possibility that Alzheimer’s Disease neuropathology evolved as a ho

  12. TWiV 1360: Clinical Update with Dr. Daniel Griffin

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello frustration continues over the increasing number of measles infections, Kennedy’s undermining of vaccines, perpetuation of autism- vaccine, autism-tylenol myths, an outbre

  13. TWiV 1359: SSPE, the Long Shadow of Measles

    Roberto Cattaneo and Kalpana Yadav join TWiV at the 2026 meeting of the American Society for Virology to discuss how the absence of measles virus receptors in the brain selects for hyperfusogenic variants that spread neuron-to-neuron and ca

  14. TWiV 1358: Clinical Update with Dr. Daniel Griffin

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello are angered by the continuous reporting of measles deaths in the US and around the world, the Ebola outbreak in Uganda, changes in reporting of virus infection and vaccine

  15. TWiV 1357: Furin, Naturally with Paul Bieniasz

    Paul Bieniasz joins TWiV to discuss his lab’s discovery that the coronavirus nuclease NSP15 cuts viral RNA into oligonucleotides that are reinserted elsewhere in the viral RNA, generating insertion mutations at a frequency above 10⁻³ per ge

  16. TWiV 1356: Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello delve into dengue virus infections in Florida, recent human rabies infections in the US, proposed changes in biomedical funding including “converting” the Department of Wa

  17. TWiV 1355: Four billion years of AI training data

    TWiV reviews a landmark paper reporting the first generative design of complete viral genomes using AI, producing 16 viable bacteriophages that overcame antibiotic-resistant bacteria where natural phages could not, and a study suggesting th

  18. TWiV 1354: Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello remember Dolly Parton and her patronage of science, especially development of the COVID-19 vaccines, if the shingles vaccine protect against cardiovascular events as well

  19. TWiV 1353: Phage bet-hedging and EBV antibodies

    TWiV explores how bacteriophages enable bet-hedge against bacterial immune defenses, and how transgenic mice engineered to produce human antibodies yielded potent anti-EBV candidates targeting gp350 and gp42, a promising step toward Epstein

  20. TWiV 1352: Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello are disheartened by the suggested change in federal vaccine recommendations, how Florida rolled back 4 childhood vaccine school requirements, results from a clinical trial

  21. TWiV 1351: Ebola Virus Brains and Contagious Catfish Cancers

    TWiV describes a human cerebral organoid model for Ebola virus persistence, and brown bullhead catfish melanoma, a novel transmissible cancer. Hosts: Vincent Racaniello (https://en.wikipedia.org/wiki/Vincent_Racaniello), Alan Dove, and Rich

  22. TWiV 1350: Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello are perplexed by the state of global public health as malaria, cholera and other infectious diseases are spread by civil warfare, the lack of manpower at the CDC to implem

  23. TWiV 1349: Smallpox and mummies

    TWiV explains how liquid–liquid phase separation and a phage-encoded inhibitor cooperatively drive transcriptional transition during phage SPO1 infection, and the first smallpox virus genomes from an early outbreak in South America. Hosts:

  24. TWiV 1348: Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello are troubled by the latest executive order changing routine childhood vaccine recommendations, the call for nominations to join the Advisory Committee for Immunization Pra

  25. TWiV 1347: No Short Answers for Long COVID

    TWiV explains research showing that Long COVID is associated with reactivation of numerous chronic viruses, including herpesviruses and anelloviruses, and with the production of autoantibodies that target neurological tissues. Hosts: Vincen

  26. TWiV 1346: Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello are distressed by Erica Schwartz’ confirmation as CDC director, the GAO proposed pandemic preparedness plans, the national cyclospora outbreak and resulting two deaths, ne

  27. TWiV 1345: Rocky Mountain Virology High

    TWiV travels to Colorado State University in Ft. Collins, where he speaks with Angela Bosco-Lauth, Rebekah Kading, and Mark Stenglein about their careers and their virology research. Host: Vincent Racaniello Guests: Angela Bosco-Lauth, Rebe

  28. TWiV 1344: Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello discuss the numerous attempts by states to roll back vaccine laws, the recent surge of Dengue virus cases in Sri Lanka, the national cyclospora outbreak, new screwworm and

  29. TWiV 1343: Batting averages and stolen bases

    TWiV explains research which shows that Per os infectivity factors are essential for bracovirus infection and wasp parasitism, and that periodic shifts in viral load increase risk of Hendra virus spillover from Pteropus bats. Hosts: Vincent

  30. TWiV 1342: Clinical update with Dr. Daniel Griffin

    In his weekly clinical update, Daniel Griffin and Vincent Racaniello explore the source/not source of the national cyclospora outbreak, trust in the FDA to correctly identify the source, new screwworm, Legionnaires and cyclosporasis cases,

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