TWiV 1361: Ancient Viral Sword and Shield

TWiV explains discovery of a previously unknown mechanism of RNA-guided DNA recognition for genetic control that possibly predates the emergence of CRISPR pathways, and the possibility that Alzheimer’s Disease neuropathology evolved as a host defense response to microbial infection in the brain.
Hosts: Vincent Racaniello (en.wikipedia.org/wiki/Vincent_Racaniello), Alan Dove (alandove.com), and Brianne Barker (bbarkerdrew.com) Subscribe (free): Apple Podcasts, RSS, email (eepurl.com/Gcw59)
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• Bob Tesh dies (Galv News)
• Comment on propsed changes to NIH peer review (NIH)
• NIH peer review proposed changes (Forbes)
• Ancient RNA guided DNA recognition (Science)
• Noncontiguous geometric triplex (Science)
• p-tau has anti-herpes virus activity (Nat Neurosci)
• Letters read (microbe.tv/twiv/twiv-1361-letters) on TWiV 1361
• Timestamps by Jolene Ramsey. Thanks!
Picks of the Week Brianne – APoD September 14: Origins of Elements Alan – Redshirts, by John Scalzi Vincent – Prone to Bruise by David Molesky he’s at Spring/Break till 9/28
Listener Pick Anne – Nikon Small World in Motion Competition
Intro music is by Ronald Jenkees
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Content in this podcast should not be construed as medical advice.