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Latent Space: The AI Engineer Podcast

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  1. Codex from 0 to 10M Users: Building ChatGPT Work — Akshay Nathan, OpenAI

    <p>There are roughly 100x more people who use code than who can write code. As code that “just works” becomes easier to generate, this group may be the biggest prize of all — if you can get the agentic interface right. A key trend we have b

  2. Inside the Model Factory — Eiso Kant, Poolside AI

    <p>In recent months, the open vs closed, and US vs China discussions on model ownership and sovereign/local AI have heated up to a fever pitch. So it is very very good news that Poolside AI are finally emerging with new models, like Laguna

  3. 🔬 Causal Models Need Causal Data - Xaira’s X-Cell model for Drug Discovery (Bo Wang & Ci Chu, Chief Discovery Officer & Chief AI Scientist)

    <p>Bet on information If test loss flatlines after 1.5B parameters while training loss continues to drop as you scale, that tells you that your model is limited by the amount of information in your data. Training on a single, smallish data

  4. 🔬 The Lab of the Future Should Feel Like a Data Center — Andy Beam & Rafa Gómez-Bombarelli, Lila Sciences

    <p>Imagine a dark warehouse. Racks and racks of devices with wires, tubes, and electronics sticking out. The next AI data center? No. This is Lila Sciences ‘ dream for the future of science. A dark warehouse full of AI-guided robotics and l

  5. ⚡️ Podcast Crossover: AIE, AGI, frontier lab strategy with ​ ⁨@matthew_berman⁩ and @swyxtv

    <p>Watch the full show on YouTube: https://www.youtube.com/watch?v=bIOCKXcxloQ</p><p><a href="https://www.youtube.com/watch?v=bIOCKXcxloQ">Full show notes and links</a></p>

  6. Why AI Infrastructure must evolve for Agent Experience — Akshat Bubna, Modal CTO

    <p>We’ve been running a bit of an Agent Cloud series surveying all the top inference/compute/cloud providers, from Databricks to Daytona to Railway and, even further back, E2B, but we’re excited to conclude this series returning to Modal, w

  7. 🔬 The Coolest Diffusion Research Isn't in LLMs — Evan Feinberg & Sergey Edunov, Genesis Molecular AI

    <p>This episode has a fun personal twist: There’s a counterfactual world where I was employee #1 at Genesis Molecular AI, the company behind today’s episode. A certain introduction happened a few weeks too late and I had already happily sig

  8. ⚡️ The Blueprint for Autonomous Work Agents | Gavriel Cohen, NanoClaw

    <p>Watch the full show on YouTube: https://www.youtube.com/watch?v=hLUGXO5DSpo</p><p><a href="https://www.youtube.com/watch?v=hLUGXO5DSpo">Full show notes and links</a></p>

  9. Why the Frontier Ecosystem must be Open — Matei Zaharia and Reynold Xin, Databricks

    <p>We’re excited to have Databricks join us at AIEWF, among hundreds of the top companies in the AI Engineer ecosystem. LS subscribers can use their discount to get past the late bird pricing and access over $50k in sponsor offers! Everyone

  10. Red-Teaming after Mythos — Zico Kolter & Matt Fredrikson, Gray Swan

    <p>AI Engineer World’s Fair regular bird tix will sell out ~today! Join us next week ahead of the Late Bird price hike and get >$40,000 in sponsor credits for attending! Thanks to the US Government issuing an export control directive on Myt

  11. ⚡️ Every product of the future will be a living system — Ronak Malde, Trajectory.ai

    <p>Watch the full show on YouTube: https://www.youtube.com/watch?v=DcvgPEApHT8</p><p><a href="https://www.youtube.com/watch?v=DcvgPEApHT8">Full show notes and links</a></p>

  12. The Professor of Outputmaxxing — Anjney Midha, AMP

    <p>Last 4 days before regular tickets sell out at AI Engineer World’s Fair - this is the single biggest gathering of AI Engineers, Founders, Leaders, and Researchers in the world. Attendees get >$5000 worth of sponsor credits and talk track

  13. 🔬 The Self-Driving Lab — Joseph Krause, Radical AI

    <p>On the Science pod, we’ve been covering a lot of the ground on how AI is revolutionizing STEM, but one of our favorite off the record topics since our launch is which field is harder to accelerate: math, bio, or physics? Today we’re back

  14. ⚡️ Making DeepSeek v4 outperform Opus 4.7 with Taste — @AhmadAwais , CommandCode.ai

    <p>Watch the full show on YouTube: https://www.youtube.com/watch?v=-rIAVuaRjOg</p><p><a href="https://www.youtube.com/watch?v=-rIAVuaRjOg">Full show notes and links</a></p>

  15. Reality: The Final Eval — Lukas Petersson and Axel Backlund of Andon Labs

    <p>The new AIEWF website is live! Get your tickets booked ASAP as they -will- sell out. Take the AI Engineering Survey and get >$2k in credits and free AIE WF tickets! Most industry benchmarks compress intelligence and reasoning ability int

  16. 🔬 Scaling Past Informal AI - Carina Hong, Axiom Math

    <p>In 2025, seven-month-old startup Axiom solved all 12 of the problems Putnam exam (scoring 8/12 in the time limit) a prestigious undergraduate math exam. The 12/12 score is better than the top undergraduates (110/120) and the closest AI s

  17. ⚡️ Satya Nadella: No Priors x Latent Space Crossover Special at Microsoft Build

    <p>We’ve informally heard that Satya is a listener to LS for a couple years now, but it was still absolutely surreal to meet him and do a live pod at Build, together with our friends at No Priors, the leading VC AI Podcast that we also grea

  18. GitHub's plan for Agents — Kyle Daigle, GitHub

    <p>I’m excited to work with Microsoft once again as the presenting sponsors of the AI Engineer World’s Fair! We’ll streaming live from MS Build today for a special crossover pod with our friends at No Priors and the one and only Satya Nadel

  19. Why Video Agent models are next — Ethan He, xAI Grok Imagine

    <p>We’re announcing AIEWF speakers this week! Take the AI Engineering Survey! Today’s guest Ethan first joined us for the LS Paper Club as the lead on NVIDIA Cosmos World Model, but then joined xAI and built Grok Imagine in 3 months: He com

  20. The Age of Async Agents — Cognition's Walden Yan & OpenInspect's Cole Murray

    <p>The new AIEWF website is live! CFPs close in 2 days and we will run our first New Engineer Orientation this weekend, get your tickets booked ASAP as they -will- sell out. Take the AI Engineering Survey and get >$2k in credits and free AI

  21. 🔬 ESM: The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub

    <p>Editor’s note: In our first BioHub pod with Priscilla and Mark they discussed their acquisition of EvoScale, led by Alex Rives, who is now Head of Science at BioHub. With ESM-1 they trained language models on millions of protein sequence

  22. ⚡️ Google's Open AI Strategy — Omar Sanseviero, Google DeepMind

    <p>Watch the full show on YouTube: https://www.youtube.com/watch?v=Hxlayqs-IAs</p><p><a href="https://www.youtube.com/watch?v=Hxlayqs-IAs">Full show notes and links</a></p>

  23. ⚡️ Why you should build Science Fiction — Sunil Pai, Cloudflare

    <p>Watch the full show on YouTube: https://www.youtube.com/watch?v=287Q-bs_pEU</p><p><a href="https://www.youtube.com/watch?v=287Q-bs_pEU">Full show notes and links</a></p>

  24. Giving Agents Computers — Ivan Burazin, Daytona

    <p>Take the 2026 AI Engineering Survey and get >$2k in credits and AIE WF tickets! On the product side, everyone is getting Computer - Perplexity, Manus, Cursor, and so on. Meanwhile on the research side, agentic evals like TerminalBench an

  25. Railway: The Agent-Native Cloud — Jake Cooper

    <p>Take the 2026 AI Engineering Survey and get >$2k in credits and AIE WF tickets! This was recorded before Railway suffered a major GCP outage on May 19, despite being a multi-AZ, multi-zone mesh ring, with HA fiber interconnects between t

  26. 🔬 The Autonomous Drone Tech Stack & Economics of Drones — Yaroslav Azhnyuk, The Fourth Law & Guest Host Noah Smith, Noahpinion

    <p>The future of war has been evolving before our eyes in Ukraine, yet the west still plans to fight the last war. In this special episode, guest host Noah Smith (@noahpinion) and Brandon Anderson sit down with Yaroslav Azhnyuk (@YaroslavAz

  27. AI-Native Healthcare: 100M Doctor Visits, 10–20 Hours Saved, Prior Auth in Minutes — Janie Lee & Chai Asawa, Abridge

    <p>Special discounts up for AIE Melbourne (LS discount) and AIE World’s Fair (group discounts up to 25% - CFPs still open for Autoresearch and Vertical AI) Cya there! Abridge did not start as an “GPT wrapper”. It was founded in 2018, years

  28. ⚡️ Senior Dev: This "Grill Me" Prompt Is Going Viral Among Top Engineers

    <p>Watch the full show on YouTube: https://www.youtube.com/watch?v=rlM_fAKxB3Q</p><p><a href="https://www.youtube.com/watch?v=rlM_fAKxB3Q">Full show notes and links</a></p>

  29. 🔬 Doing Vibe Physics — Alex Lupsasca, OpenAI

    <p>Some people are going crazy over GPT 5.5. Some people. This is the story of the Jagged Frontier. People who use AI to write emails or even code implementation work find the lift moderate whereas people pushing the limits of the model are

  30. ⚡️ Competing with ChatGPT and Sierra, building a $10M ARR company — Yasser Elsaid, Founder, Chatbase

    <p>Watch the full show on YouTube: https://www.youtube.com/watch?v=CSYWbbP_OkY</p><p><a href="https://www.youtube.com/watch?v=CSYWbbP_OkY">Full show notes and links</a></p>

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