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  1. #195 Antibiotic Duration & BALANCE Trial: Beyond Journal Club with NEJM Group

    <p>Antibiotic duration for bacteremia is something most of us learned by habit, not by trial data. In this episode, we walk through the BALANCE trial and use it as a lens to revisit how 1) host, 2) organism, and 3) source should guide treat

  2. #194: Severe Hypertriglyceridemia: 5 Pearls Segment

    <p>How quickly can triglycerides rise? At what threshold are patients at risk of pancreatitis or cardiovascular adverse outcomes? What do you have to rule out? How do you counsel on lifestyle changes? Which medications do you start with why

  3. #193 Venous Congestion & VEXUS Interview with Dr. Ross Prager

    <p>Why is venous congestion not the same as volume overload? How can looking at IVC as well as doppler on the hepatic vein, portal vein, and/or intrarenal vein help? Can venous congestion explain someone's delirium? Or be at play in septic

  4. #192 Debate on First-Line Medications for Diabetes

    <p>SGLT-2i vs. GLP-1? vs Metformin? How do you balance the cost and coverage of first-line options like metformin, SGLT-2, and GLP-1s? How do you choose between SGLT-2 and GLP-1s for comorbidities like CAD or CKD? And how do you weigh their

  5. #191 Hepatorenal Syndrome Part 2 on Management: 5 Pearls Segment

    <p>What really works when treating HRS? Vasoconstrictors like terlipressin vs. norepinephrine vs. midodrine: how do we decide which to use? Do you give albumin? When do you give Lasix or another diuretic? When is the better choice transplan

  6. #190: Hepatorenal Syndrome Part 1: 5 Pearls Segment

    <p>HRS-AKI vs. other causes of AKI in cirrhosis: What do serum or urine sodium clues, albumin challenges, and shifting diagnostic criteria actually reveal about getting the diagnosis right?</p><p>🔹 <strong>Sponsor</strong>: Oakstone CME</p

  7. #189 Bisphosphonates and Fracture Prevention Trial: Beyond Journal Club with NEJM Group

    <p><strong>Who’s really at risk for fractures, and how should we be treating them? </strong></p><p>Most fragility fractures occur in patients without osteoporosis. Should we rethink who gets treated? And could just one or two IV infusions (

  8. #188 Orthostatic Hypotension Part 2: Gray Matters Segment

    <p>Medications for orthostatic hypotension! When to initiate treatment, how to use them safely, and what to do when new issues arise during treatment. How do those change if someone has autonomic failure? What do you do when your patient ha

  9. #187 Orthostatic Hypotension Part 1: Gray Matters Segment

    <p>Learn specific, practical ways to counsel patients on non-pharmacologic interventions. What is our goal with OH treatment? Is it the blood pressure number that matters? How do we avoid missing neurogenic causes of orthostatic hypotension

  10. #186 Pneumothorax: 5 Pearls Segment

    <p>Next time you’re squinting at a chest tube, feel confident you know exactly what to look for and why. Hear it explained in a way that really sticks!</p><p>🔹 <strong>Sponsor</strong>: Oakstone CME’s ACP MKSAP Audio Companion</p><p>Use th

  11. #185 Neutropenia: 5 Pearls Segment

    <p>How do you work up neutropenia? When is neutropenia benign? When do neutrophils recover? How can you diagnose neutropenic fever in the first 15 minutes and start antibiotics in the first 60 minutes? Do you always add MRSA coverages? Only

  12. #184 Stories for the Feels

    <p>Have a good laugh and reflect deeply with these three stories that hit the feels in different ways.</p><p>If you'd love to hear more stories from Dr. Maria Rosasco, check out some of her other appearances on the podcast: <a href="https:/

  13. #183 Diagnose the Clinician: Hoofbeats Segment

    <p>What went wrong? What were the reasoning or contextual missteps that led us astray?</p><p>🔹 <strong>Sponsor</strong>:<strong> NEJM Fellowship Program, click </strong><a href="https://www.coreimpodcast.com/NEJMFellowship" rel="nofollow">

  14. #182 Pleural Effusions: 5 Pearls Segment

    <ul><li>Imaging Pearls | (01:12)</li><li>Deciding on Thoracentesis | (04:00)</li><li>Light’s Criteria and Pseudoexudates | (07:00)</li><li>Pleural Fluid Studies: pH and Cell Differential | (16:56)</li><li>Diagnosing and Treating Parapneumon

  15. #181 July Stories 3.0

    <p>Listen for some good laughs and relatable stories!</p><p>In this episode, we share raw and real stories from July — from rapid responses to unexpected kindness — and reflect on the emotional weight of starting out in medicine.</p><p>🔹 <

  16. #180 Beta-Blockers & REDUCE-AMI Trial: Beyond Journal Club Segment with NEJM Group

    <p>How much do beta blockers help after a heart attack, even when the heart’s pumping well? In this episode, we revisit the origins of <strong>beta blockers in post-MI care</strong>, examine how evidence evolved, and explore the <strong>RED

  17. #179 Invasive Fungal Disease: 5 Pearls Segment

    <p>🔹 What is invasive fungal disease, and who is most at risk for developing invasive fungal disease? (~ 02:46)</p><p>🔹 What are the main classes of fungi? (~11:35)</p><p>🔹 What are the pros and cons of B-D Glucan and Galactomannan (~19:

  18. #178 Continuous Glucose Monitor (CGM): 5 Pearls Segment

    <p>🔹What are clinically relevant limitations of an A1c vs. a CGM (1:40)</p><p>🔹What do the different parts of the ambulatory glucose profile tell you? (09:59)</p><p>🔹What are common pitfalls, medications, lifestyle patterns that are impo

  19. #177 Interventional Radiology (IR) 101: 5 Pearls Segment

    <p>🔹When is an U/S vs. CT vs. MRI helpful before consulting Interventional Radiology?</p><p>🔹What factors go into an IR pre-op evaluation?</p><p>🔹 When do drains go in, and when do they come out?</p><p>🔹 When a patient has trouble with

  20. #176 Constipation Medications: 5 Pearls Segment

    <p>🔹 High-yield reversible causes of constipation? (02:26)</p><p>🔹 Which type of fiber is more helpful? And is more hydration really better? And bulk-forming laxatives (9:03)</p><p>🔹 Osmotic vs Stimulant Laxatives (15:06)</p><p>🔹 Suppos

  21. #175 A Revolution in HIV Prevention & The PURPOSE Trials: Beyond Journal Club Segment with NEJM Group

    <p><strong>How good are we at preventing HIV?</strong> How do <strong>efficacy</strong> and <strong>effectiveness</strong> differ? We journey from <strong>oral pre-exposure prophylaxis (PrEP)</strong> to <strong>long-acting injectables</str

  22. #174 Lp(a) and ASCVD Risk: 5 Pearls Segment

    <p>What does <strong>Lipoprotein(a)</strong> tell us that a standard lipid panel doesn’t? Should we be testing <strong>everyone</strong> for it? Dive into the <strong>genetics, clinical implications, and evolving management strategies</stro

  23. #173 Hypercoagulability Workup: 5 Pearls Segment

    <p>A new way to think of clots beyond provoked vs. unprovoked: Learn all about how important it is to think about reversibility! What patient states affect the inherited thrombophilia testing? Learn the nuances and practical approaches!</p>

  24. #172 Microplastics and Macro CV Health Problems: Beyond Journal Club on APACHe Study with NEJM Group

    <p>What is the impact of microplastics on human health? How can we use observational data to support the argument that microplastics may lead to poor health outcomes?</p><p>Join us as we tackle these questions and discuss the APAChE study o

  25. #171 Hospice Music Therapy: Bonus Episode

    <p>What is the last sense to go? How can music create connection, ease anxiety, and help process emotions at the end of life? Join Dr. Jafar Al-Mondhiry, Dr. Harry Han, and music therapist Bryanna Tobin as they explore the power of music th

  26. #170 ILD and High-Risk Medication Prescribing: Gray Matters Segment

    <p>Incidental fibrosis on CT —what now? What does prone imaging tell you? Is it fibrosis, aspiration, or atelectasis? And once you diagnose ILD, does the “alphabet soup” really matter for treatment? Antifibrotics vs. immunosuppression?</p><

  27. #169 MGUS to Multiple Myeloma Diagnostics and Counseling: 5 Pearls Segment

    <p>SPEP vs. UPEP? What does it tell you and not tell you? What is the role for immunofixation and free light chains in diagnosis? Learn about paraneoplastic antibodies with MGCS and its renal, neurologic, and dermatologic manifestations!</p

  28. #168 Immune Checkpoint Inhibitor Adverse Events 2.0: 5 Pearls Segment

    <p>How do you differentiate immune checkpoint inhibitor-related adverse events aka IrAEs from other conditions like infection? Join as we go through pneumonitis, colitis, dermatitis and endocrinopathies due to immune checkpoint inhibitor to

  29. #167 Best of YouTube 2024: Anion Gap Metabolic Acidosis, Inhaler Use, Iron Deficiency in Pregnancy

    <p><strong>YouTube Videos</strong></p><ol><li>Anion Gap Metabolic Acidosis: <a href="https://youtu.be/oE0lygmMANM" rel="nofollow">https://youtu.be/oE0lygmMANM</a></li><li>Inhaler Delivery Systems: <a href="https://youtu.be/yYPdjClm9Bg" rel=

  30. #166 Stress Ulcer Prophylaxis in the ICU and REVISE Trial: Beyond Journal Club with NEJM Group

    <p>What’s the evidence been for the use of PPIs in mechanically ventilated patients? What do more recent studies reveal about PPIs and possible harmful side effects of aspiration pneumonia and C. difficile colitis? To find out, tune into th

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